Paraoxonase 1 Proteins (PON1)

The enzyme encoded by PON1 is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Additionally we are shipping Paraoxonase 1 Antibodies (166) and Paraoxonase 1 Kits (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PON1 5444 P27169
PON1 18979 P52430
PON1 84024 P55159
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Paraoxonase 1 Proteins at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$752.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$723.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,964.50
Details
Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days
$2,977.33
Details

PON1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for Paraoxonase 1 (PON1) Interaction Partners

Human Paraoxonase 1 (PON1) interaction partners

  1. The biochemical results showed significantly lower folate and vitamin B12 (show NDUFB3 Proteins) status in demented patients than controls. Global DNA methylation (show HELLS Proteins) was associated with markers of folate status, creatinine, glucose and PON1 and IL1B (show IL1B Proteins) polymorphisms.

  2. Pesticide-exposed individuals with inherited susceptible metabolic genotypes (particularly, null genotype for GSTM1 (show GSTM1 Proteins) and the PON1 192R allele) appear to have an increased risk of genotoxic DNA damage.

  3. In patients with an acute coronary syndrome, the PON1 Q192R genotypes did not influence the risk of suffering a new acute coronary event during the medium-term follow-up.

  4. PON-1 activity is impaired in rheumatoid arthritis in association with the rs662 genotype and anti-HDL (show HSD11B1 Proteins) antibodies.

  5. overexpression of PON1 in mice may contribute to the regulation of the cholesterol homeostasis

  6. Data suggest that paraoxonases (PON1, PON2 (show PON2 Proteins), PON3 (show PON3 Proteins)) play roles in innate immunity, inflammatory response, and protection against oxidative stress; these factors are associated with the body's response to infectious diseases; low serum PON1 activities are associated with poor survival in patients with severe sepsis. [REVIEW]

  7. stratification by PON1 Q192R phenotype improved the reliability characteristics of FF PON1 enzymes as biomarkers for use in clinical investigations but diminished usefulness for epidemiologic studies.

  8. report that the recombinant PON1-hFc exerts hydrolytic activity against paraoxon and DFP (show PPCS Proteins).

  9. Results suggest that DNA methylation (show HELLS Proteins) may be an underlying mechanism explaining an adverse cardio-metabolic health profile in children carrying the PON1 192R-allele and prenatally exposed to pesticides.

  10. PON1 L55M polymorphism might increase the risk of cancer [review; meta-analysis]

Mouse (Murine) Paraoxonase 1 (PON1) interaction partners

  1. PON1 overexpression protects against AAA (show AAAS Proteins) progression by reducing oxidative stress, apoptosis and inflammation

  2. Paraoxonase 1 (PON1) influence circadian gene expression and period length

  3. results suggest that Hyperhomocysteinemia plays an intricate role in dysfunctional HDL (show HSD11B1 Proteins), owing to the lack of PON1. This contributes to vascular endothelial impairment and atherosclerosis.

  4. Maternal PON1 status modulates the effects of repeated gestational chlorpyrifos oxon exposure on fetal-brain gene expression and on inhibition of both maternal and fetal biomarker enzymes.

  5. 5,6-dihydroxyeicosatrienoate-1,5-lactone, a stable metabolite of arachidonic acid, is a potential substrate for PON1.

  6. HDL (show HSD11B1 Proteins) (mostly HDL3), stimulates PON1 antiatherogenic activities in mouse macrophages.

  7. Findings suggest that Pon1 interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis

  8. The study demonstrated a significant decline in PON1 activity which correlates with increased LDL oxidation after 8 months of age in Wistar rats.

  9. PON1 plays a protective role against hepatic derangements, secondary to fat and cholesterol overnutrition. PON1 deficiency is associated with oxidative stress and metabolic alterations leading to liver steatosis.

  10. PON1 is not essential for normal development, function, ageing, and the defense against light damage of the mouse retina.

Pig (Porcine) Paraoxonase 1 (PON1) interaction partners

  1. PON1 behaves as a negative acute phase protein (show ORM1 Proteins) in pigs since a significant decrease (P<0.05) in its activity after 72 h of the induction of the inflammation was observed with all substrates.

Cow (Bovine) Paraoxonase 1 (PON1) interaction partners

  1. characterization the SNPs in the promoter region of the bovine PON1 gene, and to evaluation of association with serum PON1 activity in periparturient Holstein cows

  2. The results suggest that PON1 might be a better parameter for minimal redox state changes in serum, shortly after labour in the examined breeds.

  3. Data indicate that Cu(2+), Mn(2+), Zn(2+), Ni(2 (show VMP1 Proteins)+), and Pb(2+) were found to inhibite the paraoxonase 1 (PON1) enzyme activity in a concentration-dependent fashion.

  4. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1, 2 and 3 in granulosa cells and PON1 activity in follicular fluid and plasma of dairy cows.

  5. Significantly lower PON1 activity and PON1/high density lipoprotein ratio in lactating cows compared to heifers showed that metabolic efforts during pregnancy, parturition and lactation influence PON1 activity due to oxidative stress.

  6. The activity of PON1 and malondialdehyde in late pregnancy and early lactation in dairy cattle is reported.

Rabbit Paraoxonase 1 (PON1) interaction partners

  1. ApoE (show APOE Proteins) mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 Proteins) paraoxonase activity

  2. PON1 can decrease the AChE inhibition, and alleviated clinical signs and tissue damage caused by dichlorvos.

Paraoxonase 1 (PON1) Protein Profile

Protein Summary

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Gene names and symbols associated with Paraoxonase 1 Proteins (PON1)

  • paraoxonase 1 (pon1)
  • paraoxonase 1 (PON1)
  • paraoxonase 1 (Pon1)
  • ESA protein
  • MGC53915 protein
  • MGC89222 protein
  • MVCD5 protein
  • Pon protein
  • PON1 protein
  • pon2 protein

Protein level used designations for Paraoxonase 1 Proteins (PON1)

paraoxonase 1 , paraoxonase 2 , serum paraoxonase/arylesterase 1-like , A-esterase 1 , K-45 , PON 1 , aromatic esterase 1 , arylesterase B-type , esterase A , paraoxonase B-type , serum aryldiakylphosphatase , serum aryldialkylphosphatase 1 , serum paraoxonase/arylesterase 1 , serum paraoxonase

GENE ID SPECIES
448598 Xenopus (Silurana) tropicalis
463547 Pan troglodytes
699355 Macaca mulatta
100408915 Callithrix jacchus
100436640 Pongo abelii
100602768 Nomascus leucogenys
5444 Homo sapiens
18979 Mus musculus
84024 Rattus norvegicus
475234 Canis lupus familiaris
100048952 Sus scrofa
523798 Bos taurus
100009133 Oryctolagus cuniculus
100721268 Cavia porcellus
101116983 Ovis aries
Selected quality suppliers for Paraoxonase 1 Proteins (PON1)
Did you look for something else?