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Paroxysmal Nonkinesigenic Dyskinesia Proteins (PNKD)

PNKD is thought to play a role in the regulation of myofibrillogenesis. Additionally we are shipping PNKD Antibodies (38) and PNKD Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PNKD 25953 Q8N490
PNKD 56695 Q69ZP3
PNKD 616561 A7YY46
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Top PNKD Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,059.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PNKD Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Cow (Bovine)

More Proteins for Paroxysmal Nonkinesigenic Dyskinesia (PNKD) Interaction Partners

Human Paroxysmal Nonkinesigenic Dyskinesia (PNKD) interaction partners

  1. study highlights the frequency, novel mutations and clinical and molecular spectrum of PRRT2, SLC2A1 and PNKD mutations as well as the phenotype-genotype overlap among these paroxysmal movement disorders.

  2. This study present the pedigree is the first PNKD family from Chinese Mainland, which is also the largest PNKD family among those reported across the globe. It included 5 generations and 26 patients.

  3. MR-1 (show MR1 Proteins) functions as a tumor promoter in MCF7 cells by activating the MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) signaling

  4. MR-1 overexpression was tightly associated with more aggressive tumor behavior and a poor prognosis in pancreatic ductal adenocarcinoma.

  5. MR-1 was up-regulated in gastric cancer tissues. High expression of MR-1 in gastric cancer was significantly correlated with clinical stage. Postoperative survival of the MR-1 positive group tended to be poorer than that of the MR-1 negative group.

  6. A Taiwanese family with paroxysmal nonkinesigenic dyskinesia has a heterozygous c.20 C>T (p.Ala7Val) mutation which was clearly segregated in the five affected patients.

  7. In this report we present two families with paroxysmal non-kinesigenic dyskinesia of Southern European origin carrying a PNKD protein recurrent mutation.

  8. Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability.

  9. The pnkd mutation alters such a response, suggesting that a less flexible AC region may be more effective in coupling Ca(2 (show CA2 Proteins)+) binding to channel opening.

  10. MR-1 is a novel myofibrillogenesis regulator in human muscle

Mouse (Murine) Paroxysmal Nonkinesigenic Dyskinesia (PNKD) interaction partners

  1. PNKD KO mice, RIM1/2 protein levels are reduced and synaptic strength is impaired. Thus, PNKD is a novel synaptic protein with a regulatory role in neurotransmitter release

  2. These findings support the hypothesis that the PNKD protein functions to modulate striatal neuro-transmitter release in response to stress and other precipitating factors.

  3. these findings suggest that silencing MR-1 (show MR1 Proteins) protected mice myocardium against inflammatory injury induced by AngII by suppression of pro-inflammatory transcription factors NF-kappaB (show NFKB1 Proteins) and AP-1 (show JUN Proteins) signaling pathway.

  4. MR-1 plays an aggravative role in the development of cardiac hypertrophy via activation of the nuclear factor kappaB signaling pathway

  5. Paroxysmal non-kinesigenic dyskinesia (PNKD) is characterized by spontaneous hyperkinetic attacks that are precipitated by alcohol, coffee, stress and fatigue.

PNKD Protein Profile

Protein Summary

This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PNKD

  • paroxysmal nonkinesigenic dyskinesia (PNKD)
  • paroxysmal nonkinesiogenic dyskinesia (Pnkd)
  • 2210013N15Rik protein
  • 2810403H05Rik protein
  • AI854243 protein
  • Brp17 protein
  • DYT8 protein
  • FPD1 protein
  • KIPP1184 protein
  • MNCb-5687 protein
  • MR-1 protein
  • MR1 protein
  • PDC protein
  • PKND1 protein
  • Tahccp2 protein

Protein level used designations for PNKD

brain protein 17 , myofibrillogenesis regulator 1 , probable hydrolase PNKD , trans-activated by hepatitis C virus core protein 2 , paroxysmal nonkinesiogenic dyskinesia , paroxysmal nonkinesiogenic dyskinesia protein

GENE ID SPECIES
25953 Homo sapiens
616561 Bos taurus
56695 Mus musculus
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