anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) Antibodies

The protein encoded by PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. Additionally we are shipping PNPLA3 Kits (16) and PNPLA3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPLA3 80339 Q9NST1
PNPLA3 116939 Q91WW7
PNPLA3 362972  
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Top anti-PNPLA3 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in K562 cell line lysates (35ug/lane) using PNPLA3 Antibody (N-term) Cat.-No AP53370PU-N. This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated IHC, ELISA, WB Antibody (0.05µg/ml) staining of Mouse Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (0.01µg/ml) staining of Mouse (A) and Rat (B) Adrenal gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Dog Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Western Blot: Adiponutrin/PNPLA3 Antibody [NBP1-00227] - Staining of Mouse (A) and Rat (B) Adrenal gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Adiponutrin/PNPLA3 Antibody [NBP1-00227] - Staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated WB PNPLA3 Antibody (N-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Adiponutrin/PNPLA3 Antibody [NBP1-54611] - Sample Tissue: Human Jurkat Antibody Dilution: 1.0 ug/ml Immunohistochemistry-Paraffin: Adiponutrin/PNPLA3 Antibody [NBP1-54611] - Human Heart Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Myocardial cells (indicated with arrows) 400X magnification. 100 μL Log in to see 8 to 11 Days
$556.31
Details

PNPLA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PNPLA3 Antibodies

  1. Human Polyclonal PNPLA3 Primary Antibody for IHC, ELISA - ABIN361184 : Kumari, Schoiswohl, Chitraju, Paar, Cornaciu, Rangrez, Wongsiriroj, Nagy, Ivanova, Scott, Knittelfelder, Rechberger, Birner-Gruenberger, Eder, Brown, Haemmerle, Oberer, Lass, Kershaw, Zimmermann et al.: Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. ... in Cell metabolism 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PNPLA3 Primary Antibody for ELISA, IHC - ABIN4278479 : Steinberg, Kemp, Watt: Adipocyte triglyceride lipase expression in human obesity. in American journal of physiology. Endocrinology and metabolism 2007 (PubMed)

More Antibodies against PNPLA3 Interaction Partners

Human Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. PNPLA3 GG genotype was elevated in aggressive disease phenotype of non-alcoholic fatty liver disease.

  2. PNPLA3 was strongly expressed in the liver and clearly detectable in subcutaneous adipose tissue of obese patients. Weight loss induced by Laparoscopic gastric banding (LAGB) of severely obese patients led to significantly increased adipose, but not hepatic, tissue expression of PNPLA3. Weight loss induced by LAGB restored adipose tissue PNPLA3 expression which is suppressed by tumour necrosis factor alpha (show TNF Antibodies).

  3. Our study suggests that the pathogenic role of PNPLA3(148M) in nonalcoholic fatty liver disease is independent of the gene transcription in humans, which may be attributed to the high endogenous transcription level of PNPLA3 gene in human livers.

  4. Children carrying the T allele of the MBOAT7 polymorphism had higher plasma alanine aminotransferase than the noncarriers; children with the MBOAT7, PNPLA3, and TM6SF2 variants had the highest plasma ALT

  5. The association between the PNPLA3 variant and bipolar disorder may help guide further work on medication effectiveness, treatment options, prevention approaches, and understanding potential medication side effects among specific subgroups of individuals with the MM genotype.

  6. The PNPLA3 rs738409 GG genotype is positively associated with hepatic steatosis in Asian patients with chronic hepatitis C.

  7. The study proposes that polymorphisms in the PNPLA3 gene have highly predictive value in the development of nonalcoholic fatty liver disease and are independently associated with the severity of liver histology in patients with NAFLD (show TSC2 Antibodies).

  8. PNPLA3 association with adiposity and the risk of the nonalcoholic fatty liver disease

  9. PNPLA3 gene variant is associated with the risk of developing liver fibrosis and cirrhosis in an Eastern European population.

  10. PNPLA3 acts as a positive modulator of activated human hepatic stellate cells, affecting cytokines secretion.

Mouse (Murine) Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human 148M transgene causes steatosis.

  2. PNPLA3 plays a role in remodeling TAG in lipid droplets, as they accumulate in response to food intake

  3. adiponutrin/PNPLA3 is regulated by two key factors of the glycolytic and lipogenic pathways, raising the question of its implication in the metabolism of carbohydrates and lipids

  4. data argue against a role for Pnpla3 loss-of-function in fatty liver disease or metabolic syndrome in mice.

  5. Loss of Pnpla3 does not cause fatty liver, liver enzyme elevation, or insulin (show INS Antibodies) resistance in mice.

  6. Microarray-based gene profiling showed that the expression level of PNPLA3 in hepatocytes is correlated with that of genes associated with the lipogenic pathway such as ME1 (show ME1 Antibodies), SPOT14 (show THRSP Antibodies), and SCD1 (show SCD Antibodies).

  7. data suggest that murine ATGL (show PNPLA2 Antibodies) but not adiponutrin contributes to net adipocyte lipolysis and that ATGL (show PNPLA2 Antibodies) and adiponutrin are oppositely regulated by insulin (show INS Antibodies) both in vitro and in vivo

PNPLA3 Antigen Profile

Protein Summary

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

Gene names and symbols associated with PNPLA3

  • patatin like phospholipase domain containing 3 (PNPLA3) antibody
  • patatin-like phospholipase domain containing 3 (Pnpla3) antibody
  • Adpn antibody
  • C22orf20 antibody
  • iPLA(2)epsilon antibody

Protein level used designations for PNPLA3

acylglycerol O-acyltransferase , adiponutrin , calcium-independent phospholipase A2-epsilon , iPLA2-epsilon , iPLA2epsilon , patatin-like phospholipase domain-containing protein 3

GENE ID SPECIES
80339 Homo sapiens
116939 Mus musculus
362972 Rattus norvegicus
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