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Pellino Homolog 2 (Drosophila) Proteins (PELI2)

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Additionally we are shipping PELI2 Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PELI2 93834 Q8BST6
PELI2 57161 Q9HAT8
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Top PELI2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details

PELI2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Pellino Homolog 2 (Drosophila) (PELI2) Interaction Partners

Mouse (Murine) Pellino Homolog 2 (Drosophila) (PELI2) interaction partners

  1. Pellino 2 plays a critical role for TLR/IL-1R-mediated post-transcriptional control.

  2. Pellino-2 is a tissue-restricted component of a signaling pathway that couples the mouse pelle (show IRAK1 Proteins)-like kinase/IL-1 (show IL1A Proteins) receptor-associated kinase protein to IL-1 (show IL1A Proteins)- or lipopolysaccharide-dependent signaling.

Human Pellino Homolog 2 (Drosophila) (PELI2) interaction partners

  1. A high-affinity Pellino2 e3 ubiquitin ligase (show MUL1 Proteins) binding domain is specific for phosphothreonine motifs.

  2. Pellino 2 plays a critical role for TLR/IL-1R-mediated post-transcriptional control.

  3. interacts with TRAF6 (show TRAF6 Proteins) (tumor necrosis factor (show TNF Proteins) receptor associated factor 6) and TAK1 (transforming growth factor-beta activated kinase 1 (show MAP3K7 Proteins)); can activate the mitogen activated protein kinase (show MAPK1 Proteins) pathway

  4. Pellino2 interacts with kinase-active as well as kinase-inactive IRAK1 (show IRAK1 Proteins) and IRAK4 (show IRAK4 Proteins)

PELI2 Protein Profile

Protein Summary

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation (By similarity).

Gene names and symbols associated with PELI2

  • pellino 2 (Peli2)
  • pellino E3 ubiquitin protein ligase family member 2 (PELI2)
  • AW047589 protein
  • BB129927 protein

Protein level used designations for PELI2

E3 ubiquitin-protein ligase pellino homolog 2 , pellino-2 , protein pellino homolog 2 , pellino homolog 2

GENE ID SPECIES
93834 Mus musculus
57161 Homo sapiens
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