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Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003 [PubMed 12840023]).[supplied by OMIM, Feb 2010].. Additionally we are shipping PLIN4 Antibodies (26) and PLIN4 Kits (6) and many more products for this protein.
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PLIN2 (show PLIN2 Proteins)-PLIN5 (show PLIN5 Proteins) proteins were all more abundant in women than in men (p = 0.037 and p < 0.0001, respectively), consistent with higher intramyocellular lipid content observed in female skeletal muscle.
we found a significant association between one single-nucleotide polymorphism in PLIN4 and height but not with bone traits
These results suggest variation at the PLIN4 locus, and its interaction with PUFA as a modulator of obesity related phenotypes, acts in part through creation of a miR (show MLXIP Proteins)-522 regulatory site
Those findings indicate improvement and conservation of lifestyle depending on genetic predisposition in ADIPOQ (show ADIPOQ Proteins), PLIN (show PLIN1 Proteins) and LIPE (show LIPE Proteins) should be encouraged.
Characterization of homologous mouse gene product, plasma membrane associated protein, S3-12.
Loss of Plin4 has no effect on body weight or composition or on adipose mass or development. Triacylglycerol (TAG) content in the heart is markedly reduced. The heart of Plin4(-/-) mice displays reduced Plin5 (show PLIN5 Proteins) mRNA and protein levels.
Adipocyte protein S3-12 coats nascent lipid droplets.
Direct regulation of perilipin (show PLIN1 Proteins) and S3-12 by PPAR-gamma (show PPARG Proteins) may to be important mediator of prolonged treatment with PPAR-gamma (show PPARG Proteins) activators: insulin (show INS Proteins) sensitization, fatty acid trapping in adipose tissue, reduced basal adipose lipolysis, and weight gain.
the non-lipid droplet pools of S3-12, adipophilin (show PLIN2 Proteins), and TIP47 (show PLIN3 Proteins) constitute a ready reservoir of coat proteins to permit rapid packaging of newly synthesized triacylglycerol and to maximize energy storage during nutrient excess
Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003
, adipocyte protein S3-12
, plasma membrane associated protein, S3-12