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Pescadillo Ribosomal Biogenesis Factor 1 Proteins (PES1)

PES1 encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. Additionally we are shipping PES1 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PES1 64934 Q9EQ61
PES1 23481 O00541
PES1 289740 Q3B8N8
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Top PES1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,685.00
Details

PES1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Pescadillo Ribosomal Biogenesis Factor 1 (PES1) Interaction Partners

Mouse (Murine) Pescadillo Ribosomal Biogenesis Factor 1 (PES1) interaction partners

  1. These data suggest that PES1 is a marker of neuroblastoma (show ARHGEF16 Proteins) outcome, that it regulates neuroblastoma (show ARHGEF16 Proteins) cell proliferation, and is associated with neuroblastoma (show ARHGEF16 Proteins) differentiation.

  2. Data show that pescadillo associates with several structures that are associated with nucleogenesis, and that loss of function results in embryonic lethality due to disrupted ribosome biosynthesis.

  3. effects of PES1 and UBF1 (show UBTF Proteins) expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (show Il3 Proteins))-dependent murine myeloid cell line

  4. Interaction with Bop1 (show BOP1 Proteins) is essential for the efficient incorporation of Pes1 into nucleolar preribosomal complexes.

  5. Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.

  6. Mtap1b-Light chain 1 has the potential to repress cell proliferation by modulating the nucleolar levels of Pes1

Human Pescadillo Ribosomal Biogenesis Factor 1 (PES1) interaction partners

  1. The DDX27 (show DDX27 Proteins) can interact specifically with the Pes1 and Bop1 (show BOP1 Proteins) but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.

  2. PES1 may play important role in the progression of ovarian cancer by inversely regulating the ERalpha (show ESR1 Proteins) and ERbeta (show ESR2 Proteins) expression.

  3. these results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.

  4. Upstream of c-Jun (show JUN Proteins), it was revealed that c-Jun (show JUN Proteins) NH2-terminal kinases (JNK (show MAPK8 Proteins)) is essential for controlling PES1 expression

  5. expression of PES1 correlated positively with ERalpha (show ESR1 Proteins) expression and negatively with ERbeta (show ESR2 Proteins) expression and predicted good clinical outcome in breast cancer

  6. The physical interaction between B23 (show NPM1 Proteins) and PES1 implies that they may participate in ribosome biogenesis in a protein complex.

  7. pescadillo might play a role in promoting the proliferation and carcinogenesis of human breast cancer, and thereby might be a potential target for human breast cancer treatment.

  8. Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.

  9. RRB1 (show GRWD1 Proteins) interacts with YPH1 (yeast pescadillo homologue 1) and other members of the Yph1 complex

  10. Pes1 and Bop1 (show BOP1 Proteins) form a stable complex with a novel member, WDR12 (show WDR12 Proteins) (PeBoW complex).

Xenopus laevis Pescadillo Ribosomal Biogenesis Factor 1 (PES1) interaction partners

  1. pes1 and ppan (show PPAN Proteins) are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis

  2. pescadillo has multiple important functions during X. laevis development; pescadillo is required for eye development and neural crest migration

PES1 Protein Profile

Protein Summary

This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.

Gene names and symbols associated with PES1

  • Pescadillo (pesc)
  • pescadillo homolog 1, containing BRCT domain (zebrafish) (PES1)
  • pescadillo homolog 1, containing BRCT domain (zebrafish) (Pes1)
  • pescadillo ribosomal biogenesis factor 1 (PES1)
  • pescadillo ribosomal biogenesis factor 1 (pes1)
  • pescadillo ribosomal biogenesis factor 1 (Pes1)
  • pes protein
  • pes1 protein

Protein level used designations for PES1

pescadillo homolog , pescadillo homolog 1, containing BRCT domain

GENE ID SPECIES
100194837 Salmo salar
511676 Bos taurus
64934 Mus musculus
23481 Homo sapiens
486354 Canis lupus familiaris
100154050 Sus scrofa
380249 Xenopus laevis
289740 Rattus norvegicus
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