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Phosphatidylinositol Glycan M Proteins (PIGM)

PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. Additionally we are shipping PIGM Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PIGM 93183 Q9H3S5
PIGM 67556 Q8C2R7
Rat PIGM PIGM 79112 Q9EQY6
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Top PIGM Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PIGM Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Phosphatidylinositol Glycan M (PIGM) Interaction Partners

Arabidopsis thaliana Phosphatidylinositol Glycan M (PIGM) interaction partners

  1. PNT1 directly binds to mRNA of a key chlorophyll biosynthetic gene, protochlorophyllide reductase in vivo and inhibits the translation of PORA mRNA in the presence of phytochromes.

  2. The different phenotype of pnt1 cells in embryos and callus suggest a differential requirement for GPI (show GPI Proteins)-anchored proteins in cell wall synthesis in these two tissues and points to the importance of GPI (show GPI Proteins) anchoring in coordinated multicellular growth.

Human Phosphatidylinositol Glycan M (PIGM) interaction partners

  1. B cells but not red cells are glycosylphosphatidylinositol deficient in PIGM-associated inherited glycosylphosphatidylinositol deficiency, caused by a core promoter mutation that abrogates Sp1 (show PSG1 Proteins) binding.

  2. Studies indicate that mutations in PGM1 (show PGM1 Proteins) by exome sequencing cause hypoglycemia and liver abnormalities.

  3. Mutation substantially reduces transcription of PIGM and blocks mannosylation of glycosylphosphatidylinositol(GPI (show GNPDA1 Proteins)), leading to partial but severe deficiency of GPI (show GNPDA1 Proteins).

PIGM Protein Profile

Protein Summary

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.

Gene names and symbols associated with PIGM

  • GPI mannosyltransferase 1 (PNT1)
  • phosphatidylinositol glycan anchor biosynthesis, class M (PIGM)
  • phosphatidylinositol glycan anchor biosynthesis, class M (Pigm)
  • 4933437L05Rik protein
  • AI644422 protein
  • AV302080 protein
  • C920011G20Rik protein
  • GPI-MT-I protein
  • PEANUT 1 protein
  • PIG-M protein

Protein level used designations for PIGM

DPM:GlcN-(acyl-)PI mannosyltransferase , GPI mannosyltransferase 1 , GPI mannosyltransferase I , PIG-M mannosyltransferase , dol-P-Man dependent GPI mannosyltransferase , phosphatidylinositol-glycan biosynthesis class M protein , GPI-MT-I , PIG-M , phosphatidylinositol glycan, class M , PIG-M mRNA for mannosyltransferase

GENE ID SPECIES
832274 Arabidopsis thaliana
93183 Homo sapiens
67556 Mus musculus
79112 Rattus norvegicus
509680 Bos taurus
428583 Gallus gallus
100172653 Pongo abelii
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