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Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Proteins (PITPNM1)

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PITPNM1 18739 O35954
PITPNM1 9600 O00562
Rat PITPNM1 PITPNM1 361694 Q5U2N3
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Top Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human GST tag Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (AA 1-238), (partial) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PITPNM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Interaction Partners

Mouse (Murine) Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) interaction partners

  1. Pitpnm1 null mice showed no hearing defects.

  2. results suggest that Nir2 not only enhances EMT (show ITK Proteins) in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  3. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Human Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) interaction partners

  1. results suggest that Nir2 not only enhances EMT (show ITK Proteins) in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  2. Phosphatidic acid production triggers Phosphatidylinositol 4,5-Bisphosphate replenishment mediated by Nir2 and Nir3 (show PITPNM2 Proteins) at endoplasmic reticulum-plasma membrane junctions.

  3. Nir2 translocates from the Golgi complex to the plasma membrane in response to GF stimulation.

  4. Results suggest a feedback mechanism that replenishes PM PIP2 during receptor-induced Ca(2 (show CA2 Proteins)+) signaling via the Ca(2 (show CA2 Proteins)+) effector E-Syt1 and the PITP Nir2 at ER-PM junctions.

  5. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein (show LEPREL2 Proteins), is essential for cytokinesis.

  6. A specific Thr (show TRH Proteins) residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking & distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.

  7. Phosphorylation of Nir2 by Cdk1 (show CDK1 Proteins) facilitates its dissociation from the Golgi apparatus, and phospho-Nir2 is localized in the cleavage furrow and midbody during cytokinesis.

  8. Nir2 is involved in maintaining a critical DAG pool in the Golgi apparatus by regulating its consumption via the CDP (show CUX1 Proteins)-choline pathway

  9. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Protein Profile

Protein Summary

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005

Gene names and symbols associated with PITPNM1

  • phosphatidylinositol transfer protein, membrane-associated 1 (PITPNM1)
  • phosphatidylinositol transfer protein, membrane-associated 1 (Pitpnm1)
  • DRES9 protein
  • Mpt-1 protein
  • Nir-2 protein
  • NIR2 protein
  • PITPNM protein
  • PITPnm 1 protein
  • R75447 protein
  • Rd9 protein
  • RDGB protein
  • RDGB1 protein
  • RDGBA protein
  • RDGBA1 protein

Protein level used designations for PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1 , phosphatidylinositol transfer protein, membrane-associated 1-like , membrane-associated phosphatidylinositol transfer protein 1-like , drosophila retinal degeneration B homolog 1 , membrane-associated phosphatidylinositol transfer protein 1 , pyk2 N-terminal domain-interacting receptor 2 , retinal degeneration 9 , NIR-2 , PITPnm 1 , PYK2 N-terminal domain-interacting receptor 2 , drosophila retinal degeneration B homolog , retinal degeneration B alpha 1 , phosphatidylinositol membrane-associated

GENE ID SPECIES
533859 Bos taurus
610462 Canis lupus familiaris
721716 Macaca mulatta
769912 Gallus gallus
100408084 Callithrix jacchus
100465754 Ailuropoda melanoleuca
100547262 Meleagris gallopavo
100586982 Nomascus leucogenys
100607998 Pan troglodytes
18739 Mus musculus
9600 Homo sapiens
361694 Rattus norvegicus
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