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anti-Platelet Endothelial Aggregation Receptor 1 (PEAR1) Antibodies

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PEAR1 Proteins (7) and PEAR1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PEAR1 375033 Q5VY43
PEAR1 73182 Q8VIK5
PEAR1 295293  
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Top anti-PEAR1 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PEAR1 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by  DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of PEAR1 Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PEAR1 in rat kidney tissue lysate with PEAR1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB PEAR1 antibody (C-term) (ABIN654292) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse PE FACS   100 Tests Log in to see 8 to 10 Days
$903.83
Details
Human Goat Un-conjugated FACS, ELISA, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Alexa Fluor 700 FACS   0.1 mg Log in to see 8 to 11 Days
$427.88
Details
Human Mouse Alexa Fluor 647 FACS   0.1 mg Log in to see 8 to 11 Days
$427.88
Details
Human Mouse Alexa Fluor 750 FACS   0.1 mg Log in to see 8 to 11 Days
$427.88
Details
Human Mouse Alexa Fluor 594 FACS   0.1 mg Log in to see 8 to 11 Days
$427.88
Details

PEAR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)


Top referenced anti-PEAR1 Antibodies

  1. Human Polyclonal PEAR1 Primary Antibody for EIA, IHC (p) - ABIN954080 : Johnson, Yanek, Chen, Faraday, Larson, Tofler, Lin, Kraja, Province, Yang, Becker, ODonnell, Becker: Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. in Nature genetics 2010 (PubMed)
    Show all 4 references for ABIN954080

  2. Human Polyclonal PEAR1 Primary Antibody for EIA, WB - ABIN783779 : Nanda, Bao, Lin, Clauser, Komuves, Quertermous, Conley, Phillips, Hart: Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against PEAR1 Interaction Partners

Human Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  2. Results suggest that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.

  3. FcepsilonRI (show FCER1G Antibodies) alpha-chain (show FCGRT Antibodies) is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand.

  4. genetic variability of GAS6 (show GAS6 Antibodies) and PEAR1 genes may be associated with platelet hyperaggregability

  5. A common genetic variant in PEAR1 (rs12041331) reproducibly influenced platelet aggregation in aspirin-treated patients with coronary artery disease.

  6. study suggests that PEAR1 is not a hypertension susceptibility gene in humans.

  7. The SNPs in two regions of the PEAR1 gene, from rs3737224 to rs822442, and from rs1214331 to rs12566888, probably play important roles in prasugrel pharmacodynamics

  8. additional exonic variants in PEAR1 that may also determine variability in platelet aggregation, were identified.

  9. A-allele carriers of rs12041331 in the platelet endothelial aggregation receptor-1 (PEAR1) gene were more likely to experience a cardiovascular event or death compared with GG homozygotes

  10. PEAR1 attenuates megakaryopoiesis via control of the PI3K (show PIK3CA Antibodies)/PTEN (show PTEN Antibodies) pathway.

Mouse (Murine) Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  2. Jedi-1 signals through recruitment of GULP (show GULP1 Antibodies), which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.

  3. These results indicated that both Jedi-1 and MEGF10 (show MEGF10 Antibodies) can mediate phagocytosis independently through the recruitment of Syk (show SYK Antibodies).

  4. Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch (show NOTCH1 Antibodies) signaling pathway.

  5. a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein

PEAR1 Antigen Profile

Protein Summary

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005

Gene names and symbols associated with PEAR1

  • platelet endothelial aggregation receptor 1 (PEAR1) antibody
  • platelet endothelial aggregation receptor 1 (pear1) antibody
  • platelet endothelial aggregation receptor 1 (LOC100338327) antibody
  • platelet endothelial aggregation receptor 1 (Pear1) antibody
  • 3110045G13Rik antibody
  • JEDI antibody
  • Jedi-1 antibody
  • Megf12 antibody
  • RGD1305653 antibody

Protein level used designations for PEAR1

platelet endothelial aggregation receptor 1 , multiple EGF-like-domains 12 , platelet endothelial aggregation receptor 1-like , hPEAR1 , multiple EGF-like domains protein 12 , multiple epidermal growth factor-like domains protein 12 , Jedi , jagged and Delta protein , mPEAR1 , protein Jedi

GENE ID SPECIES
457409 Pan troglodytes
490403 Canis lupus familiaris
571812 Danio rerio
718698 Macaca mulatta
787112 Bos taurus
100023818 Monodelphis domestica
100064623 Equus caballus
100338327 Oryctolagus cuniculus
100451525 Pongo abelii
100586891 Nomascus leucogenys
375033 Homo sapiens
73182 Mus musculus
295293 Rattus norvegicus
Selected quality suppliers for anti-PEAR1 (PEAR1) Antibodies
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