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anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) Antibodies

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Additionally we are shipping PLEKHG6 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLEKHG6 55200 Q3KR16
PLEKHG6 213522 Q8R0J1
PLEKHG6    
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Top anti-PLEKHG6 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MyoGEF Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). MyoGEF (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of MyoGEF Antibody (N-term) (ABIN390909) in NCI-H460 cell line lysates (35 µg/lane). MyoGEF (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma with MyoGEF Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PLEKHG6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PLEKHG6 Antibodies

  1. Human Polyclonal PLEKHG6 Primary Antibody for EIA, WB - ABIN453207 : DAngelo, Aresta, Blangy, Del Maestro, Louvard, Arpin: Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells. in Molecular biology of the cell 2007 (PubMed)

More Antibodies against PLEKHG6 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) interaction partners

  1. Intramolecular interactions between MyoGEF domains act as an autoinhibitory mechanism for the regulation of MyoGEF functions.

  2. Taken together, these results suggest that aurora B (show AURKB Antibodies) coordinates with Plk1 (show PLK1 Antibodies) to regulate MyoGEF activation and localization, thus contributing to the regulation of cytokinesis.

  3. GIPC1 (show GIPC1 Antibodies)-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.

  4. ezrin (show EZR Antibodies) allows the local activation of RhoG (show RHOG Antibodies) at the apical pole of epithelial cells by recruiting upstream and downstream regulators of RhoG (show RHOG Antibodies) and that both PLEKHG6 and ezrin (show EZR Antibodies) are required for efficient macropinocytosis

  5. Plk1 (show PLK1 Antibodies) can regulate MyoGEF activity and localization, contributing to the regulation of cytokinesis

  6. MyoGEF cooperates with nonmuscle myosin IIA to regulate the polarity and invasion activity of breast cancer cells through activation of RhoA (show RHOA Antibodies) and RhoC (show RHOC Antibodies).

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) interaction partners

  1. GIPC1 (show GIPC1 Antibodies)-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.

PLEKHG6 Antigen Profile

Protein Summary

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Gene names and symbols associated with PLEKHG6

  • pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (PLEKHG6) antibody
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (Plekhg6) antibody
  • BC026778 antibody
  • Gm155 antibody
  • MyoGEF antibody

Protein level used designations for PLEKHG6

PH domain-containing family G member 6 , myosin interacting guanine nucleotide exchange factor , myosin-interacting guanine nucleotide exchange factor , pleckstrin homology domain-containing family G member 6

GENE ID SPECIES
55200 Homo sapiens
213522 Mus musculus
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