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Poly(A) Binding Protein Interacting Protein 1 Proteins (PAIP1)

The protein encoded by PAIP1 interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. Additionally we are shipping Poly(A) Binding Protein Interacting Protein 1 Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PAIP1 10605 Q9H074
Rat PAIP1 PAIP1 365684  
PAIP1 218693 Q8VE62
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Top Poly(A) Binding Protein Interacting Protein 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,303.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PAIP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Poly(A) Binding Protein Interacting Protein 1 (PAIP1) Interaction Partners

Human Poly(A) Binding Protein Interacting Protein 1 (PAIP1) interaction partners

  1. Data provide evidence that the stability of Paip1 can be regulated by ubiquitin-mediated degradation, thus highlighting the importance of WWP2 (show WWP2 Proteins) as a suppressor of translation.

  2. The Paip1-eIF3 (show EIF3A Proteins) interaction is impaired by the mTORC1 inhibitors.

  3. the crystal structure of the middle domain of Paip1 isoform 2 (Paip1M) as determined by single-wavelength anomalous dispersion phasing is reported.

  4. Paip1 is translational activator in 5' cap-dependent translation by interacting with PABP (show PABPC1 Proteins) & initiation factors eIF4A (show EIF4A1 Proteins) & eIF3 (show EIF3A Proteins). Crystallization & preliminary diffraction analysis of middle domain of Paip1 gives crystals that diffract to resolution of 2.2 A.

  5. Paip1 interacts with poly(A) binding protein through two independent binding motifs.

  6. eIF3 (show EIF3A Proteins)-Paip1 stabilizes the interaction between PABP (show PABPC1 Proteins) and eIF4G (show EIF4G1 Proteins), which brings about the circularization of the mRNA.

Poly(A) Binding Protein Interacting Protein 1 (PAIP1) Protein Profile

Protein Summary

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Gene names and symbols associated with PAIP1

  • poly(A) binding protein interacting protein 1 (paip1)
  • poly(A) binding protein interacting protein 1 (PAIP1)
  • poly(A) binding protein interacting protein 1 (Paip1)
  • polyadenylate binding protein-interacting protein 1 (Paip1)
  • fb53g01 protein
  • wu:fb53g01 protein
  • zgc:91954 protein

Protein level used designations for PAIP1

polyadenylate-binding protein-interacting protein 1 , poly(A) binding protein interacting protein 1 , polyadenylate-binding protein-interacting protein 1-like , PABP-interacting protein 1 , PAIP-1 , poly(A)-binding protein-interacting protein 1 , polyadenylate binding protein-interacting protein 1 , xlPaip1 , PABC1-interacting protein 1

GENE ID SPECIES
445110 Danio rerio
100038239 Xenopus (Silurana) tropicalis
100038266 Xenopus (Silurana) tropicalis
100460862 Pongo abelii
100587906 Nomascus leucogenys
100614277 Pan troglodytes
380223 Xenopus laevis
427195 Gallus gallus
10605 Homo sapiens
479343 Canis lupus familiaris
510246 Bos taurus
365684 Rattus norvegicus
218693 Mus musculus
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