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anti-Polymerase I and Transcript Release Factor (PTRF) Antibodies

PTRF encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. Additionally we are shipping Polymerase I and Transcript Release Factor Proteins (6) and Polymerase I and Transcript Release Factor Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTRF 284119 Q6NZI2
PTRF 19285 O54724
PTRF 287710  
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Top anti-Polymerase I and Transcript Release Factor Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-PTRF Antibody Titration: 0.625ug/mlELISA Titer: 1:31... IHC Information: Paraffin embedded mouse vessel and adipocytes (skelet... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-PTRF Antibody (N-term) Pab in A375 cell ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue react... Western blot analysis of anti-PTRF Antibody (N-term) in A375 cell line... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PTRF Antibody (N-term) (ABIN391621) in A... Formalin-fixed and paraffin-embedded human lung carcinoma tissue react... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-PTRF Antibody (N-term) Pab (ABIN391622) ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), ELISA Immunoperoxidase of monoclonal antibody to PTRF on formalin-fixed para... 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Mouse Vessel and Adipocytes: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Mouse Un-conjugated IHC (p), ELISA Immunoperoxidase of monoclonal antibody to PTRF on formalin-fixed para... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

PTRF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Polymerase I and Transcript Release Factor Antibodies

  1. Human Polyclonal PTRF Primary Antibody for EIA, WB - ABIN359583 : Aboulaich, Ortegren, Vener, Strålfors: Association and insulin regulated translocation of hormone-sensitive lipase with PTRF. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 3 references for ABIN359583

  2. Human Polyclonal PTRF Primary Antibody for EIA, IHC (p) - ABIN359582 : Hasegawa, Takeuchi, Miyaishi, Xiao, Mao, Isobe: PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters. in The Biochemical journal 2000 (PubMed)
    Show all 3 references for ABIN359582

  3. Human Monoclonal PTRF Primary Antibody for IHC (p), ELISA - ABIN567012 : Hansen, Bright, Howard, Nichols: SDPR induces membrane curvature and functions in the formation of caveolae. in Nature cell biology 2009 (PubMed)

  4. Cow (Bovine) Polyclonal PTRF Primary Antibody for IHC, WB - ABIN2779886 : Miyoshi, Cui, Riedlinger, Robinson, Lehoczky, Zon, Oka, Dewar, Hennighausen: Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse. in Genomics 2001 (PubMed)

  5. Human Polyclonal PTRF Primary Antibody for IHC (p), WB - ABIN391621 : Park, Yamaura, Kawamoto, Kurihara, Sato: Reciprocal modulation of surface expression of annexin A2 in a human umbilical vein endothelial cell-derived cell line by eicosapentaenoic acid and docosahexaenoic acid. in PLoS ONE 2014 (PubMed)

More Antibodies against Polymerase I and Transcript Release Factor Interaction Partners

Human Polymerase I and Transcript Release Factor (PTRF) interaction partners

  1. This study reports an unanticipated function of ROR1 (show ROR1 Antibodies) as a scaffold of cavin-1 and caveolin-1 (show CAV1 Antibodies), two essential structural components of caveolae.

  2. Cavin-1 and cavin-2 (show SDPR Antibodies) are strongly expressed within caveolae-like structures within liver sinusoidal endothelial cells of the hepatitis C-related cirrhotic liver and cavin-1 would play a critical role in regulating aspects of caveolin-1 (show CAV1 Antibodies).

  3. Rather than forming a single coat complex containing the three cavin family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1, cavin2 (show SDPR Antibodies) and cavin3 (show PRKCDBP Antibodies).

  4. Our data support a role for PTRF/cavin-1, through caveolae formation, as an attenuator of the non-caveolar functionality of Cav1 (show CAV1 Antibodies) in Gal3 (show LGALS3 Antibodies)-Cav1 (show CAV1 Antibodies) signalling and regulation of focal adhesion dynamics and cancer cell migration.

  5. this study presents a novel mutation of PTRF from Saudi Arabia and our findings broaden the mutation spectrum of PTRF in the familial CGL4 phenotype.

  6. cavin3 (show PRKCDBP Antibodies) is recruited to the caveolae coat by cavin1 to interact with caveolin1 and regulate the duration time of caveolae at the plasma membrane.

  7. The presence of caveolae as an anatomic structure is not sufficient to ensure their proper function in patient with PTRF mutation.

  8. Using in silico and in vitro analysis we show that Cavin-1 is expressed in myogenic Rhabdomyosarcoma tumors and human and primary mouse RMS cultures. Cavin-1 or Cav-1 (show CAV1 Antibodies) knockdown led to impairment of cell proliferation and migration.

  9. PTRF acts as a modulator in GBM chemoresistance

  10. In human adipose tissue, P (show C9orf3 Antibodies)TRF mRNA levels positively correlated with markers of lipolysis and cellular senescence. A negative relationship between telomere length and PTRF mRNA levels was observed in human subcutaneous fat.

Mouse (Murine) Polymerase I and Transcript Release Factor (PTRF) interaction partners

  1. these results suggested that the membrane dynamics in cell migration is affected by caveolae associated PTRF/cavin-1.

  2. study demonstrates a critical role of cavin-1 in vascular structure and function, but the influences on arterial resistance cancel each other such that arterial blood pressure remains unaltered in homeostatic conditions

  3. lipid mobilization in cultured adipocytes to induce lipid droplet shrinkage led to biphasic response of cavin-1 with ultimate loss of expression of cavin-1 by protein degradation.

  4. A Western-type diet in apo (show C9orf3 Antibodies)-E2 knock-in mice produced 3 groups of obese mice with PTRF expression correlating with glucose tolerance: normal, hyperinsulinemic glucose-tolerant, or impaired. PTRF compromised adipocyte differentiation of 3T3-L1 cells.

  5. Adipocytes from cavin-1-null mice are markedly dysfunctional exhibiting decreased insulin (show INS Antibodies)-dependent glucose uptake, fatty acid uptake, and lipolysis.

  6. PTRF is a crucial regulator of TLR4 (show TLR4 Antibodies) signaling in the development of sepsis.

  7. an important role for Cavin1 in lung homeostasis

  8. Cavin-1 is critical for detrusor caveolae and for overall contractility and structure of the urinary bladder.

  9. Cavin-1 modulates cellular polarization, and the subcellular localization of Rac1 and caveolin-1 (show CAV1 Antibodies) in migrating cells as well as PKCalpha (show PKCa Antibodies) caveola recruitment.

  10. Double-immunogold labeling showed that the caveolae-shaping molecule PTRF/cavin 1 behaved similarly and that syndapin II (show PACSIN2 Antibodies) and PTRF/cavin 1 colocalized.

Polymerase I and Transcript Release Factor (PTRF) Antigen Profile

Protein Summary

This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Gene names and symbols associated with PTRF

  • polymerase I and transcript release factor (ptrf) antibody
  • polymerase I and transcript release factor (PTRF) antibody
  • polymerase I and transcript release factor b (ptrfb) antibody
  • polymerase I and transcript release factor (Ptrf) antibody
  • 2310075E07Rik antibody
  • AW546441 antibody
  • Cav-p60 antibody
  • Cavin antibody
  • cavin-1 antibody
  • CAVIN1 antibody
  • CGL4 antibody
  • fd20g07 antibody
  • MGC53017 antibody
  • MGC89141 antibody
  • ptrf antibody
  • wu:fd20g07 antibody
  • zgc:162917 antibody

Protein level used designations for PTRF

polymerase I and transcript release factor , leucine zipper protein , leucine-zipper protein , polymerase I and transcript release factor-like , RNA polymerase I and transcript release factor , TTF-I interacting peptide 12 , cavin-1 , cav-p60 , cavin

GENE ID SPECIES
380268 Xenopus laevis
396006 Gallus gallus
448589 Xenopus (Silurana) tropicalis
454684 Pan troglodytes
561082 Danio rerio
100411410 Callithrix jacchus
284119 Homo sapiens
490966 Canis lupus familiaris
538457 Bos taurus
19285 Mus musculus
287710 Rattus norvegicus
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