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anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) Antibodies

PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping PTBP1 Kits (9) and PTBP1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTBP1 302879  
PTBP1 5725 P26599
PTBP1 19205  
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Top anti-PTBP1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PTBP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PTBP1 Antibody Titration: 0.2-1 ug/mlPositive Control: Daudi cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185079 staining (1µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN185079 (0.1 µg/mL) staining of Human Ovary lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB PTBP1 Antibody (N-term) (ABIN1881702) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the PTBP1 antibody detected the PTBP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with PTBP1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PTBP1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Skin (formalin-fixed, paraffin-embedded) stained with PTBP1 antibody ABIN461929 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PTBP1 antibody ABIN461929 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details

PTBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)
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Human , , ,
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Mouse (Murine)
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Top referenced anti-PTBP1 Antibodies

  1. Human Polyclonal PTBP1 Primary Antibody for WB - ABIN1881702 : Osada, Uno, Mineta, Kameoka, Takahashi, Terao: Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta. in Molecular ecology 2010 (PubMed)
    Show all 5 references for ABIN1881702

  2. Chicken Polyclonal PTBP1 Primary Antibody for WB - ABIN2778815 : Somberg, Zhao, Fröhlich, Evander, Schwartz: Polypyrimidine tract binding protein induces human papillomavirus type 16 late gene expression by interfering with splicing inhibitory elements at the major late 5' splice site, SD3632. in Journal of virology 2008 (PubMed)
    Show all 2 references for ABIN2778815

  3. Chicken Polyclonal PTBP1 Primary Antibody for WB - ABIN2778814 : Robinson, Smith: A splicing repressor domain in polypyrimidine tract-binding protein. in The Journal of biological chemistry 2006 (PubMed)

  4. Human Polyclonal PTBP1 Primary Antibody for IHC, ELISA - ABIN185079 : Charlet-B, Logan, Singh, Cooper: Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. in Molecular cell 2002 (PubMed)

More Antibodies against PTBP1 Interaction Partners

Xenopus laevis Polypyrimidine Tract Binding Protein 1 (PTBP1) interaction partners

  1. inactivation of both exosc9, which encodes a component of the RNA exosome, and ptbp1, which encodes an RNA-binding protein abundant in Xenopus embryonic skin, impairs embryonic Xenopus skin development.

  2. Polypyrimidine tract binding protein prevents activity of an intronic regulatory element that promotes usage of a composite 3'-terminal exon

Human Polypyrimidine Tract Binding Protein 1 (PTBP1) interaction partners

  1. The polypyrimidine tract binding protein 1 (PTBP1) shields specific retroviral and cellular transcripts from nonsense-mediated mRNA decay.

  2. findings point to PKM2 and PTBP1 as new potential therapeutic targets to improve response of PDAC to chemotherapy

  3. PTBP1 and PTBP2 (show PTBP2 Antibodies) impaired autoregulation of SRSF3 (show SRSF3 Antibodies) in oral squamous cell carcinoma cancer cells.

  4. Results suggest that the role of polypyrimidine tract binding protein 1 (PTBP1) in tumorigenesis may be partly mediated by its regulation of cdc42 (show CDC42 Antibodies) GTP-binding protein (CDC42 (show CDC42 Antibodies)) alternative splicing and CDC42 (show CDC42 Antibodies)-v2 might function as a tumor suppressor.

  5. Data indicate that polypyrimidine tract-binding protein (PTBP1) is preferentially overexpressed in clinical colorectal cancers

  6. PTB/hnRNP1 binds to the 3'UTR (show UTS2R Antibodies) of Human Astrovirus-8 and is required or participates in viral replication.

  7. Data show that the protein levels of polypyrimidine tract binding protein 1 (PTBP1) and adenosine deaminase RNA-specific (show ADAR Antibodies) binding protein ADAR1 (show ADAR Antibodies) were cooperatively expressed in glioma tissues and cells.

  8. Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms

  9. HUR (show ELAVL1 Antibodies) competes with the host protein PTB, which is a negative regulator of hepatitis C virus replication.

  10. RBFOX proteins can facilitate the splicing of micro-exons. We also found that PTBP1 likely regulates the inclusion of micro-exons, possibly by repressing the inclusion of micro-exons that are enhanced by RBFOX proteins and other splicing factors.

Mouse (Murine) Polypyrimidine Tract Binding Protein 1 (PTBP1) interaction partners

  1. Thus, PTBP1 controls the activity of Pbx1 (show PBX1 Antibodies) to suppress its neuronal transcriptional program prior to induction of neuronal progenitor cells development.

  2. showed polypyrimidine tract binding protein (PTBP)-dependent alternative splicing of CaMKIIalpha (show CAMK2 Antibodies) transcripts in the lens

  3. This may account for the tight correlation between Hps1 with Ptbp1 expression levels observed across mammalian tissues.

  4. The expression levels of three splicing factors, ESRP1 (show ESRP1 Antibodies), PTB and SF2/ASF (show SRSF1 Antibodies), are significantly altered during cardiac hypertrophy in mice.

  5. Study reports that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR (show MLXIP Antibodies)-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons.

  6. PTB regulates the precise expression of CDK11(p58 (show CDK11B Antibodies)) through direct interaction with CDK11(p58 (show CDK11B Antibodies)) IRES and promotes M phase progression in ES cells.

  7. The polypyrimidine tract binding proteins PTBP1 and PTBP2 (show PTBP2 Antibodies) repressed Psd-95 (show DLG4 Antibodies) (also known as Dlg4 (show DLG4 Antibodies)) exon 18 splicing, leading to premature translation termination and nonsense-mediated mRNA decay.

  8. PTBP1 is not required for the earliest isovolumetric divisions and differentiation steps of the zygote up to the formation of the blastocyst.

  9. RBM4 (show RBM4 Antibodies) may synergize its effect on muscle cell-specific alternative splicing by down-regulating PTB expression and antagonizing the activity of PTB in exon selection

  10. splicing repressors hnRNP A1 and A2, as well as the polypyrimidine-tract-binding protein PTB, contribute to control of pyruvate kinase isoform M1 and M2 expression

Zebrafish Polypyrimidine Tract Binding Protein 1 (PTBP1) interaction partners

  1. Data report on a zebrafish maternal-effect (show NLRP5 Antibodies) mutant, brom bones, which is defective in the cytosolic Ca(2 (show CA2 Antibodies)+) rise and subsequent egg activation events, including cortical granule exocytosis and cytoplasmic segregation [brom bones].

  2. Two stretches of polypyrimidine tracts designated PPT1 and PPT2 which influence the IRES activity of cx55.5 protein were identified; deletion of PPT1 results in an appreciable decrease of the IRES activity

Arabidopsis thaliana Polypyrimidine Tract Binding Protein 1 (PTBP1) interaction partners

  1. PTB1 is a splicing factor (show SLU7 Antibodies) that influences alternative splicing and acts at the polypyrimidine tract.

  2. Alternative splicing (AS) patterns as well as the expression of key flowering regulators were massively changed in a PTB1/2 level-dependent manner.

  3. AtPTB1 and AtPTB2 are widely expressed in almost all tissues, with the highest expression levels in late-maturing and mature pollen grains, and are crucial for pollen germination. [AtPTB1]

PTBP1 Antigen Profile

Protein Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with PTBP1

  • polypyrimidine tract binding protein 1 (ptbp1-b) antibody
  • polypyrimidine tract-binding protein (Smptb) antibody
  • polypyrimidine tract-binding protein (NAEGRDRAFT_80143) antibody
  • polypyrimidine tract-binding protein (LOC100285404) antibody
  • polypyrimidine tract binding protein 1 (PTBP1) antibody
  • polypyrimidine tract binding protein 1 (ptbp1-a) antibody
  • polypyrimidine tract binding protein 1 (Ptbp1) antibody
  • polypyrimidine tract binding protein 1a (ptbp1a) antibody
  • polypyrimidine tract-binding protein 1 (PTB1) antibody
  • AA407203 antibody
  • AL033359 antibody
  • ATPTB1 antibody
  • HNRNP-I antibody
  • HNRNPI antibody
  • HNRPI antibody
  • POLYPYRIMIDINE TRACT-BINDING antibody
  • polypyrimidine tract-binding protein 1 antibody
  • pPTB antibody
  • ptb antibody
  • PTB-1 antibody
  • PTB-T antibody
  • PTB2 antibody
  • PTB3 antibody
  • PTB4 antibody
  • ptbp1 antibody
  • Pybp antibody
  • Pybp1 antibody
  • Pybp2 antibody
  • T4P13.16 antibody
  • T4P13_16 antibody
  • vgrbp60 antibody
  • wu:fb99f12 antibody
  • zgc:110689 antibody

Protein level used designations for PTBP1

polypyrimidine tract binding protein 1 , hnrnp I , hnRNP I-related RNA transport protein VgRBP60 , polypyrimidine tract-binding protein , PTB , polypyrimidine tract-binding protein 1 , 57 kDa RNA-binding protein PPTB-1 , RNA-binding protein , heterogeneous nuclear ribonucleoprotein I , heterogeneous nuclear ribonucleoprotein polypeptide I , hnRNP I , polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) , pyrimidine binding protein 1 , pyrimidine binding protein 2 , brb , brom bones

GENE ID SPECIES
399134 Xenopus laevis
302879 Rattus norvegicus
8853259 Naegleria gruberi strain NEG-M
100285404 Zea mays
282018 Bos taurus
5725 Homo sapiens
379861 Xenopus laevis
485097 Canis lupus familiaris
397461 Sus scrofa
19205 Mus musculus
29497 Rattus norvegicus
323490 Danio rerio
821129 Arabidopsis thaliana
420098 Gallus gallus
Selected quality suppliers for anti-PTBP1 (PTBP1) Antibodies
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