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Potassium Channel, Subfamily K, Member 10 Proteins (KCNK10)

The protein encoded by KCNK10 belongs to the family of potassium channel proteins containing two pore-forming P domains. Additionally we are shipping Potassium Channel, Subfamily K, Member 10 Antibodies (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNK10 54207 P57789
Mouse KCNK10 KCNK10 72258  
Rat KCNK10 KCNK10 65272 Q9JIS4
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Top Potassium Channel, Subfamily K, Member 10 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

KCNK10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Potassium Channel, Subfamily K, Member 10 (KCNK10) Interaction Partners

Human Potassium Channel, Subfamily K, Member 10 (KCNK10) interaction partners

  1. This study showed that KCNK10 gene involved in neuronal growth and cerebellum development and associated with neurological and psychological disorders.

  2. The selectivity filter conformations of alternative translation initiation isoforms and wild type human TREK-2 are similar in the S4 site and pHo position.

  3. Results suggest that the cytosolic C-terminal domain and the bottom of transmembrane segment M2 are required for the 2-aminoethoxydiphenyl borate activation on TREK-2 channels

  4. How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK (show KCNK4 Proteins), TREK1 (show KCNK2 Proteins), and TREK2.

  5. Modulation of K2P 2.1 and K2P 10.1 K(+) channel (show KCNC4 Proteins) sensitivity to carvedilol by alternative mRNA translation initiation

  6. PLD2 (show PLD2 Proteins), but not PLD1, directly binds to the C terminus of TREK1 (show KCNK2 Proteins) and TREK2.

  7. crystal structures of TREK-2 channel in 2 conformations and in complex with norfluoxetine, a state-dependent blocker of TREK (show KCNK2 Proteins) channels; results provide an explanation for TREK (show KCNK2 Proteins) channel mechanosensitivity, regulation by diverse stimuli and possible off-target effects of Prozac

  8. High TREK-2 expression is associated with epithelial ovarian cancer.

  9. Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2.

  10. Predicts the role of TREK-2 in brain ischemia, memory and other tissues.[REVIEW]

Mouse (Murine) Potassium Channel, Subfamily K, Member 10 (KCNK10) interaction partners

  1. The results suggest that positive modulation of the TREK2 channel may have beneficial analgesic effects in these neuropathic conditions.

  2. Two novel splice isoforms of Trek2 are characterized, both showing prominent expression in the central nervous system and suggesting a potential role for Trek2 amino terminus in channel trafficking and/or stability.

  3. KCNK10 plays an important role in the early stages of preadipocyte differentiation.

  4. TREK (show KCNK2 Proteins) channels may represent the AMPK (show PRKAA1 Proteins)-inhibited background K(+) channels that mediate activation of glomus cells by hypoxia.

  5. TREK-2 contributes to the background K+ conductance in MIN6 cells, and may regulate depolarization-induced secretion of insulin (show INS Proteins)

  6. TREK-1 (show KCNK2 Proteins), TREK-2, and TRAAK (show KCNK4 Proteins) are lysophosphatidic acid-operated K+ channels

  7. Identification of the large-conductance background K+ channel (show KCNC4 Proteins) in mouse B cells as TREK-2.

  8. Data show thatA single conserved residue, H126 in TREK1 (show KCNK2 Proteins) and H151 in TREK2, is involved in proton sensing.

Potassium Channel, Subfamily K, Member 10 (KCNK10) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with KCNK10

  • potassium channel, subfamily K, member 10 (KCNK10)
  • potassium channel, subfamily K, member 10 (Kcnk10)
  • potassium channel, subfamily K, member 10 (kcnk10)
  • 1700024D23Rik protein
  • 3010005K24Rik protein
  • k2p10.1 protein
  • KCNK10 protein
  • trek-2 protein
  • trek2 protein

Protein level used designations for KCNK10

potassium channel, subfamily K, member 10 , 2P domain potassium channel TREK2 , TREK-2 K(+) channel subunit , TWIK-related K+ channel 2 , outward rectifying potassium channel protein TREK-2 , potassium channel TREK-2 , potassium channel subfamily K member 10 , TREK-2 two-pore-domain K+ channel , outward rectifying potassium channel TREK2

GENE ID SPECIES
428902 Gallus gallus
525109 Bos taurus
736753 Pan troglodytes
54207 Homo sapiens
490822 Canis lupus familiaris
100009503 Oryctolagus cuniculus
72258 Mus musculus
65272 Rattus norvegicus
446288 Xenopus laevis
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