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Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 Proteins (5) and Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 Kits (2) and many more products for this protein.
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Dog (Canine) Polyclonal KCNJ16 Primary Antibody for WB - ABIN2776226
Ji, Foo, ORoak, Zhao, Larson, Simon, Newton-Cheh, State, Levy, Lifton: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. in Nature genetics 2008
Kir4.1 (show KCNJ10 Antibodies) and Kir5.1 potassium channels bind with a heteromeric interaction that influences rectification, gating, and pH sensitivity
these results suggest that the Kir4.1-Kir5.1 but not the homomeric Kir4.1 channel is strongly inhibited by PKC activation.
Gene expression levels of three randomly selected DEGs (show DEGS1 Antibodies), VCAN (show Vcan Antibodies), COL5A1 (show COL5A1 Antibodies) and KCNJ16, were examined using RT-PCR in 10 ATC (show SRPK1 Antibodies) samples.. angiogenesis was activated by the high expression of CTHRC1 (show CTHRC1 Antibodies), VCAN (show Vcan Antibodies) and POSTN (show POSTN Antibodies), providing necessary nutrition for tumor cells
Variability has been found in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel approximately 1 Mb deletion upstream of SOX9 (show SOX9 Antibodies), and including KCNJ2 (show KCNJ2 Antibodies) and KCNJ16.
Five de novo mutations were identified in four genes (SCNN1A (show SCNN1A Antibodies), KCNJ16, KCNB2 (show KCNB2 Antibodies), and KCNT1 (show KCNT1 Antibodies)) in three Brugada syndrome patients
study provides an explanation for the pathophysiology of the p.A167V KCNJ10 (show KCNJ10 Antibodies) mutation, which had not been considered pathogenic on its own; findings provide evidence for functional cooperation of KCNJ10 (show KCNJ10 Antibodies) and KCNJ16; in vitro ascertainment of KCNJ10 (show KCNJ10 Antibodies) function may necessitate co-expression with KCNJ16
Down-regulation of Kir5.1 is associated with the decline in auditory function in aging mice.
thyroglobulin (show TG Antibodies) trafficking might be modulated by Kir4.1 (show KCNJ10 Antibodies)/5.1.
Kir5.1 is inhibited in cortical collecting duct cells by dopamine
These results highlight the important role that Kir5.1 plays as a pH-sensitive regulator of salt transport in the DCT (show DCT Antibodies), and the implication of these results for the correct genetic diagnosis of renal tubulopathies is discussed.
Kir5.1 may be involved in the response to hypercapnic acidosis
Kir4.1 (show KCNJ10 Antibodies)/5.1 and Kir4.1 (show KCNJ10 Antibodies) expression appeared to occur only in astrocytes, specifically in the membrane domains facing the pia (show RICTOR Antibodies) mater (show NLRP5 Antibodies) and blood vessels or in the processes surrounding synapses.
the Kir4.1 (show KCNJ10 Antibodies)/Kir5.1 channel is a major component of the K(+) conductance in the basolateral membrane of mouse cortical collecting duct principal cells
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium\; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.
potassium inwardly-rectifying channel, subfamily J, member 16
, potassium inwardly-rectifying channel J16
, inward rectifier potassium channel 16
, inwardly-rectifying potassium channel Kir5.1
, inward rectifier K(+) channel Kir5.1
, inward rectifier K+ channel KIR5.1
, potassium channel, inwardly rectifying subfamily J member 16
, potassium inwardly-rectifying channel subfamily J member 16