anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) Antibodies

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNJ6 3763 P48051
KCNJ6 16522 P48542
KCNJ6 25743 P48550
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Top anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238558 (1µg/ml) staining of Human Brain (Substantia Nigra) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB KCNJ6 Antibody (Center) (ABIN652033) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the KCNJ6 antibody detected the KCNJ6 protein (arrow). KCNJ6 Antibody (Center) (ABIN652033) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$595.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Bat Rabbit Un-conjugated IHC (p) Anti-KCNJ6 / GIRK2 antibody  ABIN1048986 IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Cow Rabbit Un-conjugated IHC (p) Anti-KCNJ6 / GIRK2 antibody  ABIN1048987 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of NIH3T3 and mouse brain cells, using KCNJ6 antibody. 100 μL Log in to see 16 Days
$275.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of rat brain membranes: 1. Anti-Kir3.2 (GIRK2) antibody, (1:200). 2. Anti-Kir3.2 (GIRK2) antibody, preincubated with the control antigen. 25 μL Log in to see 10 to 11 Days
$535.71
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 12 to 14 Days
$541.80
Details

KCNJ6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Antibodies

  1. Human Polyclonal KCNJ6 Primary Antibody for ELISA, WB - ABIN238558 : Lu, Lin, Huang, Kang, Rich, Lo, Myszka, Han, Wu: XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. in Molecular cell 2007 (PubMed)

More Antibodies against Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) interaction partners

  1. The major findings of the current study are 1 (show VPS52 Antibodies)) an additive genotypic effect of the KCNJ6 SNP on the ERO (show OPN3 Antibodies) theta power phenotype during reward processing, increasing significantly across genotypes.

  2. Three of the four KCNJ6 SNPs studied here were found to be significantly associated with the same theta event related oscillations in adults.

  3. The findings of this study suggest that variations in KCNJ6 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.

  4. KCNJ6 (GIRK2) gene polymorphism rs2835859 could serve as a marker that predicts sensitivity to analgesics and pain and susceptibility to nicotine dependence.

  5. In this transgenic mouse model, GIRK2 plays a major role in the genesis of infantile spasms.

  6. Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel (show KCNJ1 Antibodies) encoded by KCNJ6.

  7. For KCNJ6, three SNPs (i.e., rs2835914, rs8129919, rs2836050) were associated with the occurrence of preoperative breast pain.

  8. Ethanol associates directly with the GIRK channel, leading to enhanced interaction with a membrane phospholipid phosphatidylinositol 4,5-bisphosphate and activation of the channel.

  9. 3.5 A resolution crystal structure of the mammalian GIRK2 channel in complex with betagamma G-protein subunits, the central signalling complex that links G-protein-coupled receptor (show ADRA1A Antibodies) stimulation to K(+) channel (show KCNC4 Antibodies) activity

  10. KCNJ6 (or its product GIRK2) accounts for some of the variations in frontal theta; band oscillations.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) interaction partners

  1. The GABABR-coupled GIRK2 channel is necessary for the GABABR agonist-induced infantile spasms phenotype in the Ts mouse and may represent a novel therapeutic target for the treatment of infantile spasms in Down syndrome.

  2. It was concluded that GIRK2, through its dual responsiveness to G protein beta (show GNB3 Antibodies)-gamma and Na+, mediates a form of neuronal inhibition that is amplifiable in the setting of excess electrical activity.

  3. cholesterol did not affect the unitary conductance of GIRK2, it significantly enhanced the frequency of channel openings.

  4. Results indicate that GIRK channels formed by GIRK2 subunits determine depression-related behaviors as well as basal and 5-HT1A receptor (show CC2D1A Antibodies)-mediated dorsal raphe neuronal activity

  5. This study showed that spontaneous GIRK2 mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  6. This study demonstrated that the residue Ser-196 in Kir3.2 is involved in conferring PKC-mediated inhibition to the channel.

  7. In the ventral tegmental area, GABA neurons express both GIRK2 (and GIRK1 (show KCNJ3 Antibodies)) subunits.

  8. Gbeta (show SUCLG2 Antibodies)-gamma and PIP2 must be present simultaneously to activate GIRK2.

  9. Ligand-operated activation of Kir3.2 appears to cause dilation of the pore at the cytoplasmic domain, and is regulated conformationally.

  10. A subcellular GIRK2c/GIRK3 (show KCNJ9 Antibodies) pathway is identified that regulates excitability of ventral tegmental area dopamine neurons.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) Antigen Profile

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.

Gene names and symbols associated with KCNJ6

  • potassium inwardly-rectifying channel, subfamily J, member 6 (KCNJ6) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 6 (kcnj6) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 6 (Kcnj6) antibody
  • BIR1 antibody
  • GIRK-2 antibody
  • GIRK2 antibody
  • hiGIRK2 antibody
  • KATP-2 antibody
  • KATP2 antibody
  • kcnj6 antibody
  • KCNJ7 antibody
  • Kir3.2 antibody
  • weaver antibody
  • wv antibody

Protein level used designations for KCNJ6

potassium inwardly-rectifying channel, subfamily J, member 6 , G-protein-coupled inward rectifier potassium channel , G protein-activated inward rectifier potassium channel 2 , inward rectifier K(+) channel Kir3.2 , inward rectifier potassium channel KIR3.2 , GIRK-2 , potassium channel, inwardly rectifying subfamily J member 6 , potassium inwardly-rectifying channel J6 , BIR1 , GIRK2 , KATP-2 , Inward rectifier K(+) channel Kir3.2 , Potassium channel, inwardly rectifying subfamily J member 6 , potassium channel-like protein

GENE ID SPECIES
427983 Gallus gallus
520743 Bos taurus
549655 Xenopus (Silurana) tropicalis
100625084 Sus scrofa
3763 Homo sapiens
16522 Mus musculus
25743 Rattus norvegicus
101823647 Mesocricetus auratus
100174134 Pongo abelii
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