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PFDN5 encodes a member of the prefoldin alpha subunit family. Additionally we are shipping PFDN5 Kits (13) and PFDN5 Proteins (11) and many more products for this protein.
Showing 10 out of 84 products:
Human Polyclonal PFDN5 Primary Antibody for ELISA, WB - ABIN562181
Yoshida, Kitaura, Hagio, Sato, Iguchi-Ariga, Ariga: Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene. in Experimental cell research 2008
Show all 2 references for ABIN562181
Human Polyclonal PFDN5 Primary Antibody for ICC, IF - ABIN4344988
Rogers, Gahring: Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. in PLoS ONE 2015
a genetic disruption in the murine Pfdn5 gene, a subunit of prefoldin, causes a syndrome characterized by photoreceptor degeneration, central nervous system abnormalities, and male infertility
MM-1 may play a role in liver development and growth.
knockdown of PFD2 (show PFDN2 Antibodies) and PFD5 disrupted prefoldin formation in HTT (show HTT Antibodies)-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT (show HTT Antibodies) and in induction of cell death.
Rabring7 (show RNF115 Antibodies) stimulates c-Myc (show MYC Antibodies) degradation via mono-ubiquitination of MM-1
interaction with p73 (show TP73 Antibodies)
MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc (show MYC Antibodies)
Wnt4 (show WNT4 Antibodies) gene, a member of the Wnt (show WNT2 Antibodies)-beta-catenin (show CTNNB1 Antibodies) pathway, was identified as a target gene of MM-1.
MM-1, a c-Myc (show MYC Antibodies) interacting protein, interacts with HCV ARFP/F protein (show HPD Antibodies), which can result in the enhancement of the c-Myc (show MYC Antibodies) activity.
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
prefoldin subunit 5
, Prefoldin subunit 5
, C-myc-binding protein Mm-1
, c-myc binding protein MM-1
, myc modulator 1
, c-myc binding protein
, myc modulator-1
, prefoldin 5