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PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1\; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PNCK Proteins (7) and PNCK Kits (1) and many more products for this protein.
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Human Polyclonal PNCK Primary Antibody for IHC (p), WB - ABIN391139
Deb, Coticchia, Barndt, Zuo, Dickson, Johnson: Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation. in American journal of physiology. Cell physiology 2008
Show all 2 references for ABIN391139
Pnck may be a marker of Trastuzumab resistance and possibly a therapeutic target in breast cancer.
the relationship between PNCK and prognosis in clear cell renal cell carcinoma (show MOK Antibodies)
Pnck induces epidermal growth factor receptor (show EGFR Antibodies) degradation, most likely through perturbation of Hsp90 chaperone (show HSP90 Antibodies) activity due to Hsp90 (show HSP90 Antibodies) phosphorylation. Epidermal growth factor receptor (show EGFR Antibodies) degradation is coupled to proteasomal degradation of Pnck.
Pnck induces ligand-independent EGFR (show EGFR Antibodies) degradation, and it may represent an attractive therapeutic target in EGFR (show EGFR Antibodies)-regulated oncogenesis.
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1\; MIM 604998) (Gardner et al., 2000
caM kinase I beta
, caM kinase IB
, caM-KI beta
, calcium/calmodulin-dependent protein kinase type 1B
, pregnancy up-regulated non-ubiquitously-expressed CaM kinase
, pregnancy upregulated non-ubiquitously expressed CaM kinase
, calcium/calmodulin-dependent protein kinase 1, beta
, pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog
, calcium/calmodulin-dependent protein kinase 1 beta