Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) ELISA Kits

PAPPA encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Additionally we are shipping PAPPA Antibodies (400) and PAPPA Proteins (20) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PAPPA 18491 Q8R4K8
PAPPA 313262  
PAPPA 5069 Q13219
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Top PAPPA ELISA Kits at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.116 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$832.83
Details
Mouse 0.065 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$852.24
Details
Rat 0.094 ng/mL 0.156-10 ng/mL Diagramm of the ELISA kit to detect Rat PAPP-Awith the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 12 to 14 Days
$638.00
Details
Human 31.2 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 2 to 3 Days
$526.90
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for PAPPA Interaction Partners

Mouse (Murine) Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) interaction partners

  1. Intrinsic mitochondrial oxidative capacity was significantly increased in skeletal muscle of aged PAPP-A KO compared to WT mice. Moreover, 18-month-old PAPP-A KO mice exhibited significantly enhanced endurance running on a treadmill. Thus, PAPP-A deficiency in mice is associated with indices of healthy skeletal muscle function with age.

  2. Snell, GHKRO, and PAPPA-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT ELISA Kits)) and N-myc downstream-regulated gene 1 (NDRG1 (show NDRG1 ELISA Kits)).

  3. STC2 (show STC2 ELISA Kits) is involved in regulating PAPP-A activity during the development of atherosclerosis

  4. Study demonstrates proof-of-principle and provides feasibility for a novel therapeutic strategy to inhibit atherosclerotic plaque burden by selective targeting of PAPP-A.

  5. stimulation of PAPP-A expression by intermittent PTH (show PTH ELISA Kits) treatment contributes to PTH (show PTH ELISA Kits) bone anabolism in mice

  6. PAPP-A affects fascicle structure, thereby affecting tendon phenotype.

  7. PAPP-A has a role in development of advanced plaque with necrotic cores and buried fibrous caps (show CAPS ELISA Kits) in the brachiocephalic artery

  8. these data indicate preferential impact of PAPP-A deficiency on visceral fat in the mouse that is associated with enhanced insulin receptor (show INSR ELISA Kits) signaling

  9. Studies show a conditional PAPP-A knockout (KO) model for efficacy of tamoxifen-induced floxed PAPP-A excision in various tissues and indicate a significant reduction of neointimal formation after unilateral carotid artery ligation.

  10. absence of PAPP-A is associated with resistance to the development of indicators of diabetic nephropathy in mice

Human Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) interaction partners

  1. PAPP-A, like CCS (show CCS ELISA Kits) and CIMT, is a parameter that can be used to detect subclinical atherosclerosis.

  2. Results suggest that links between PAPP-A concentrations in early pregnancy and subsequent glucose concentrations and blood pressures may be mediated by changes in insulin (show INS ELISA Kits) sensitivity (and secretion).

  3. Collectively, these results identify PAPP-A as a pregnancy-dependent oncogene (show RAB1A ELISA Kits) while also showing that extended lactation is protective against PAPP-A-mediated carcinogenesis.

  4. Lower PlGF (show PGF ELISA Kits) and higher PAPP-A and free beta-hCG (show CGA ELISA Kits) levels were found in the fetal circulation of near-term severe preeclamptic pregnancies

  5. PAPP-A 1224 SNP has a significant effect on the level and activity of PAPP-A in human follicles, suggesting that the follicular fluid level of bioactive insulin (show INS ELISA Kits)-like growth factor depends on the genotype.

  6. This study demonstrated no association between PAPP-A gene rs7020782 polymorphism and Preeclampsia (PE) and intrauterine growth restriction.

  7. data indicate that PAPP-A promotes TF expression in human endothelial cells and support the hypothesis that this proteinase, besides being involved in progression of atherosclerosis, does not represent an independent risk factor for adverse cardiovascular events, but it rather might play an "active" role in the pathophysiology of ACS (show PLA2G15 ELISA Kits) as an effector molecule able to induce a pro-thrombotic phenotype in endothelial cells

  8. assessed serum PAPP-A levels in COPD (show ARCN1 ELISA Kits) and the associations with disease severity; elevated levels of PAPP-A were observed in patients with COPD (show ARCN1 ELISA Kits)

  9. STC2 (show STC2 ELISA Kits) is involved in regulating PAPP-A activity during the development of atherosclerosis

  10. Data suggest that stanniocalcin 1 (show STC1 ELISA Kits) and 2 (STC1 (show STC1 ELISA Kits), STC2 (show STC2 ELISA Kits)) participate in inhibition of proteolytic activity of pregnancy-associated plasma protein-A (PAPP-A) during folliculogenesis.

Cow (Bovine) Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) interaction partners

  1. study determined IGFR1 (show IGF1R ELISA Kits) and PAPP-A expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (show SNRPB ELISA Kits)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 (show IGF1R ELISA Kits) expression and PAPP-A secretion as a modulator of IGF1 (show IGF1 ELISA Kits) in cattle with COD (show SNRPB ELISA Kits)

  2. in preovulatory follicles, PAPP-A is responsible for IGF-dependent IGFBP-2 (show IGFBP2 ELISA Kits) degradation

  3. concluded that changes in granulosa cell PAPP-A mRNA levels do not occur during final preovulatory follicular development in cattle

PAPPA Antigen Profile

Antigen Summary

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

Gene names and symbols associated with PAPPA

  • pregnancy-associated plasma protein-A (PAPP-A) antibody
  • pregnancy-associated plasma protein A (Pappa) antibody
  • pregnancy-associated plasma protein A, pappalysin 1 (PAPPA) antibody
  • pregnancy-associated plasma protein A, pappalysin 1 (Pappa) antibody
  • 8430414N03Rik antibody
  • ASBABP2 antibody
  • DIPLA1 antibody
  • IGFBP-4ase antibody
  • PAG1 antibody
  • PAPA antibody
  • PAPP-A antibody
  • Pappa antibody
  • PAPPA1 antibody

Protein level used designations for PAPPA

IGF-dependent IGFBP-4 protease , insulin-like growth factor-dependent IGF-binding protein 4 protease , pappalysin-1 , aspecific BCL2 ARE-binding protein 2 , differentially placenta 1 expressed protein , insulin-like growth factor-dependent IGF binding protein-4 protease , pregnacy-associated plasma protein A , PAPPA-like protein , pregnancy-associated plasma protein A-like protein , cleaves insulin-like binding protein-4 (IGFBP-4) , metalloprotease

GENE ID SPECIES
100033920 Equus caballus
18491 Mus musculus
313262 Rattus norvegicus
5069 Homo sapiens
481692 Canis lupus familiaris
282647 Bos taurus
100734958 Cavia porcellus
417245 Gallus gallus
397219 Sus scrofa
443157 Ovis aries
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