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Premelanosome Protein (PMEL) ELISA Kits

PMEL encodes a melanocyte-specific type I transmembrane glycoprotein. Additionally we are shipping PMEL Antibodies (242) and PMEL Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PMEL 6490 P40967
PMEL 20431  
Anti-Rat PMEL PMEL 362818  
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Top PMEL ELISA Kits at antibodies-online.com

Showing 7 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Mouse
78-5000 pg/mL   96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

Top referenced PMEL ELISA Kits

  1. Human PMEL ELISA Kit for Sandwich ELISA - ABIN414624 : Bande, Santiago, Mera, Piulats, Blanco, Rodríguez-Álvarez, Capeans, Piñeiro, Pardo: ME20-S as a Potential Biomarker for the Evaluation of Uveal Melanoma. in Investigative ophthalmology & visual science 2015 (PubMed)

More ELISA Kits for PMEL Interaction Partners

Human Premelanosome Protein (PMEL) interaction partners

  1. Data suggest that the Kringle-like domain of PMEL facilitates post-endoplasmic reticulum processing of disulfide-bonded PMEL dimers and promotes formation of PMEL functional amyloid fibrillar structures within multivesicular endosomes.

  2. mutant N-terminally extended peptides exhibited significantly increased HLA-A*02:01 binding affinity and elicited CD8 (show CD8A ELISA Kits)(+) T cell stimulation in vitro similar to the wtgp100209-217 epitope.

  3. Data indicate that repeat domain (RPT) derived from Pmel17 aggregation kinetics were influenced only by lysolipid-containing phospholipid vesicles.

  4. Melanosome-autonomous regulation of size and number: the OA1 (show GPR143 ELISA Kits) receptor sustains PMEL expression.

  5. SIL-TAL1 (show TAL1 ELISA Kits) rearrangement identifies a distinct subtype with inferior outcome which could allow for individual therapeutic stratification for T-ALL patients.

  6. the molecular basis for the distinct trafficking and morphogenetic properties of PMEL and GPNMB is the PKD (show PRKD1 ELISA Kits) domain

  7. Data indicat that the N-terminal region of PMEL/Pmel17 is essential for the formation of melanosomal fibrils.

  8. BACE2 cle (show BACE ELISA Kits)aves the integra (show BACE2 ELISA Kits)l membrane form of PMEL within the juxtamembrane domain, releasing the PMEL luminal domain into endosomal precursors for the formation of amyloid fibrils and downstream melanosome morphogenesis.

  9. The recombinant Pmel 17 plasmids were right as we expected by DNA sequencing

  10. The most significant single-nucleotide polymorphism in the 12q13.2 locus is located immediately upstream of the promoter region of PMEL for vitiligo in Han Chinese.

Cow (Bovine) Premelanosome Protein (PMEL) interaction partners

  1. Six solid colors occur in Highland cattle: black, dun, silver dun and red, yellow, and white. These six coat colors are explained by a non-epistatic interaction of the genotypes at the MC1R (show MSHR ELISA Kits) and PMEL genes.

  2. no convincing recombination events were found between the SILV c.64A>G mutation and the Dc locus

  3. the complex expression pattern of the bovine SILV gene in pigmented and non-pigmented tissues

Mouse (Murine) Premelanosome Protein (PMEL) interaction partners

  1. Prophylactic and therapeutic vaccinations of mice with MCMV-gp100KGP effectively protected mice from highly aggressive lung B16-F10 (show F10 ELISA Kits) melanoma, and the protection was mediated by gp100-specific CD8 (show CD8A ELISA Kits)(+) T cells

  2. Melanosome-autonomous regulation of size and number: the OA1 (show GPR143 ELISA Kits) receptor sustains PMEL expression.

  3. the BACE1 (show BACE ELISA Kits) homologue BACE2 (show BACE2 ELISA Kits) processes PMEL to generate functional amyloids

  4. A long-peptide vaccine formulation of 20-mer (show ERH ELISA Kits) synthetic peptide elicits gp100-specific CD8 (show CD8A ELISA Kits) T cells from the endogenous repertoire.

  5. Despite a mild effect on visible pigmentation, inactivation of Pmel led to a substantial reduction in eumelanin content in hair, which demonstrates that PMEL has a critical role for maintaining efficient epidermal pigmentation.

  6. Pmel17 gene expression is Microphthalmia-associated transcription factor (show MITF ELISA Kits)-dependent in the mouse embryo.

  7. These data reveal a dual sorting defect in a natural mutant of Pmel17 and support a requirement of endocytic trafficking in Pmel17 fibril formation.

PMEL Antigen Profile

Antigen Summary

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Premelanosome Protein (PMEL) ELISA Kits

  • premelanosome protein (PMEL) antibody
  • premelanosome protein (Pmel) antibody
  • D10H12S53E antibody
  • D12S53E antibody
  • D12S53Eh antibody
  • gp87 antibody
  • gp100 antibody
  • ME20 antibody
  • ME20-M antibody
  • ME20M antibody
  • MMP115 antibody
  • P1 antibody
  • P100 antibody
  • Pmel17 antibody
  • RPE1 antibody
  • Si antibody
  • SIL antibody
  • Silv antibody

Protein level used designations for Premelanosome Protein (PMEL) ELISA Kits

melanocyte protein PMEL , melanocyte protein Pmel 17 , melanocyte protein mel 17 , melanocytes lineage-specific antigen GP100 , melanoma-associated ME20 antigen , melanosomal matrix protein17 , silver locus protein homolog , silver, mouse, homolog of , silver homolog , retinal pigment epithelial-specific protein , melanocyte protein pmel 17 , silver locus protein , 115 kDa melanosomal matrix protein , PMEL17 protein

GENE ID SPECIES
6490 Homo sapiens
481102 Canis lupus familiaris
594851 Sus scrofa
281487 Bos taurus
20431 Mus musculus
362818 Rattus norvegicus
396007 Gallus gallus
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