anti-Prodynorphin (PDYN) Antibodies

The protein encoded by PDYN is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. Additionally we are shipping PDYN Kits (24) and PDYN Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDYN 5173 P01213
PDYN 18610  
PDYN 29190  
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Top anti-PDYN Antibodies at

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-PDYN Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (fro), IHC (p), RIA   0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-Pdyn Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate WB Suggested Anti-Pdyn  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.93T cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB Western Blot: PDYN Antibody [NBP1-91500] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate. 100 μL Log in to see 8 to 11 Days
Guinea Pig Rabbit Un-conjugated IHC (fro), RIA   0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB Western blot analysis of ProDynorphin expression in Hela (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
REACT_Broad Bean Mouse Un-conjugated ELISA   0.2 mg Log in to see 3 to 4 Days
Mammalian Mouse Un-conjugated IHC   500 μL Log in to see 2 to 3 Days

PDYN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PDYN Antibodies

  1. Mouse (Murine) Polyclonal PDYN Primary Antibody for WB - ABIN611204 : Agarwal, Baek, Jeon, Miyamoto, Ueno, Yoon: Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS. in Biochemistry 1991 (PubMed)
    Show all 4 references for 611204

  2. Human Polyclonal PDYN Primary Antibody for IHC (fro), IHC (p) - ABIN121536 : Beck, Goussakov, Lie, Helmstaedter, Elger: Synaptic plasticity in the human dentate gyrus. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 (PubMed)
    Show all 3 references for 121536

  3. Guinea Pig Polyclonal PDYN Primary Antibody for IHC (fro), RIA - ABIN121537 : Neal, Newman et al.: Prodynorphin peptide distribution in the forebrain of the Syrian hamster and rat: a comparative study with antisera against dynorphin A, dynorphin B, and the C-terminus of the prodynorphin precursor ... in The Journal of comparative neurology 1989 (PubMed)
    Show all 2 references for 121537

  4. Mammalian Monoclonal PDYN Primary Antibody for IHC - ABIN283766 : Commons: Neuronal pathways linking substance P to drug addiction and stress. in Brain research 2010 (PubMed)

  5. Human Polyclonal PDYN Primary Antibody for WB - ABIN4894853 : Jiang, Wang, Li, Mo, Song, Tang, Feng: Electroacupuncture relieves labour pain and influences the spinal dynorphin/κ-opioid receptor system in rats. in Acupuncture in medicine : journal of the British Medical Acupuncture Society 2016 (PubMed)

More Antibodies against PDYN Interaction Partners

Xenopus laevis Prodynorphin (PDYN) interaction partners

  1. The Xen-dorphin prohormone is a new opioid-like prohormone distinct from proenkephalin (show PENK Antibodies) and prodynorphin.

Rhesus Monkey Prodynorphin (PDYN) interaction partners

  1. Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence.

Human Prodynorphin (PDYN) interaction partners

  1. This study found a significant haplotype-by-sex interaction, suggesting association with alcohol dependence in males but not females. The findings suggest that sex-dependent effects of PDYN variants in alcohol dependence are phenotype-specific.

  2. PDYN gene promoter polymorphism might contribute to familial-risk temporal lobe epilepsy. (Review, meta-analysis)

  3. The results demonstrate that DYN 1-17 and certain N-terminal fragments, produced in an inflamed environment, play an anti-inflammatory role by inhibiting NF-kappaB (show NFKB1 Antibodies)/p65 (show GORASP1 Antibodies) translocation.

  4. Enhanced event-related potentials amplitudes suggest a hyper-active performance monitoring system in high PDYN expression individuals, and this might also be an indicator of a higher risk for internalizing disorders

  5. This study generated the first mouse model for SCA23 and shown that mice expressing PDYN-R212W recapitulate many characteristics of the human phenotype of SCA23

  6. Studied differential DNA-protein interactions of PDYN and OPRK1 (show OPRK1 Antibodies) SNPs significantly associated with alcohol dependence.

  7. REST represses PDYN expression in SH-SY5Y cells and the adult human brain and may have implications for mental health and brain/mental disorders.

  8. This study demonistratedn that Neurocognitive and neuroinflammatory correlates of PDYN mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects.

  9. Data indicate that the minor allele of PDYN rs2281285 was associated with an increased risk of drinking to avoid/escape unwanted emotional or somatic events.

  10. To investigate the frequency of SCA23 among the Chinese Han population, we performed polymerase chain reaction (PCR) and DNA direct sequencing of the PDYN gene in 305 unrelated ataxia (show USP14 Antibodies) patients

Pig (Porcine) Prodynorphin (PDYN) interaction partners

  1. The expression of the genes coding for proopiomelanocortin (POMC (show POMC Antibodies)), proenkephalin (PENK (show PENK Antibodies)) and prodynorphin (PDYN) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.

Mouse (Murine) Prodynorphin (PDYN) interaction partners

  1. DYN-A(2-17) interacts with Orexin A in the paraventricular hypothalamic nucleus to modulate food intake in mice.

  2. We found potential links between the alterations in expression of Tsc22d3 (show TSC22D3 Antibodies), Nfkbia (show NFKBIA Antibodies) and Pdyn, and different aspects of susceptibility to stress.

  3. This study identify that photostimulation of dyn-expressing cells in discrete subregions within the NAcSh drive opposing motivational behavioral states

  4. The results of this study indicated that PDYN have a differential role in cue-induced reinstatement of cocaine-seeking behavior.

  5. Double NPY (show NPY Antibodies) and dynorphin deletion resulted in heavier mice, with increased adiposity, despite no significant changes in food intake or UCP-1 (show UCP1 Antibodies) activity.

  6. These findings identify a unique cellular process by which orexin (show OX Antibodies) can occlude the reward threshold-elevating effects of coreleased dynorphin and thereby act in a permissive fashion to facilitate reward.

  7. Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R (show TACR3 Antibodies) and KOR (show OPRK1 Antibodies)) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).

  8. The results of this study suggested that elevated Pdyn expression during normal aging reduces mGluR (show GRM8 Antibodies) expression and signaling, which in turn impairs cognitive functions and increases anxiety.

  9. Thus the dynorphin system, acting via neuropeptide y (show NPY Antibodies), may represent a pathway by which higher processes including stress, reward/addiction and depression influence skeletal metabolism

  10. sex and genetic background have an effect on anxiety-related and stress-induced behaviour of prodynorphin-deficient mice

Cow (Bovine) Prodynorphin (PDYN) interaction partners

  1. The investigation of Dyn (show SPTBN4 Antibodies) A 1-17 metabolism at the blood-brain barrier (BBB (show ALMS1 Antibodies)) is important since the metabolites exhibit unique biological functions compared to the parent compound.

PDYN Antigen Profile

Protein Summary

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Prodynorphin (PDYN) Antibodies

  • prodynorphin (pdyn-a) antibody
  • prodynorphin (pdyn) antibody
  • prodynorphin (PDYN) antibody
  • Beta-neoendorphin-dynorphin (pdyn) antibody
  • beta-neoendorphin-dynorphin (LOC100341339) antibody
  • prodynorphin (Pdyn) antibody
  • ADCA antibody
  • Dyn antibody
  • olpa antibody
  • olpb antibody
  • pdyn antibody
  • PENKB antibody
  • SCA23 antibody
  • wu:fj38c03 antibody
  • Xen-dorphin antibody
  • XOLPA antibody
  • XOLPB antibody

Protein level used designations for anti-Prodynorphin (PDYN) Antibodies

prodynorphin , dorphin A , dorphin B , fj38c03 , beta-neoendorphin-dynorphin , Beta-neoendorphin-dynorphin , proenkephalin-B , proenkephalin-B preproprotein , proenkephalin-b , leu-enkephalin , leumorphin , neoendorphin-dynorphin-enkephalin prepropeptide , preprodynorphin , preproenkephalin B , rimorphin , proenkephalin B

403367 Xenopus laevis
403368 Xenopus laevis
414850 Danio rerio
469860 Pan troglodytes
485808 Canis lupus familiaris
716341 Macaca mulatta
100195894 Salmo salar
100294654 Ovis aries
100341339 Oryctolagus cuniculus
100528666 Ictalurus punctatus
5173 Homo sapiens
445529 Sus scrofa
100135596 Cavia porcellus
18610 Mus musculus
29190 Rattus norvegicus
281385 Bos taurus
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