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PGRMC1 encodes a putative membrane-associated progesterone steroid receptor. Additionally we are shipping PGRMC1 Proteins (11) and PGRMC1 Kits (1) and many more products for this protein.
Showing 10 out of 41 products:
Human Polyclonal PGRMC1 Primary Antibody for ICC, IF - ABIN4345137
Glaser, DeMorrow, Francis, Ueno, Gaudio, Vaculin, Venter, Franchitto, Onori, Vaculin, Marzioni, Wise, Pilanthananond, Savage, Pierce, Mancinelli, Alpini: Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms. in American journal of physiology. Gastrointestinal and liver physiology 2008
Show all 12 references for ABIN4345137
Cow (Bovine) Polyclonal PGRMC1 Primary Antibody for IHC, WB - ABIN2782728
Peluso, Liu, Saunders, Claffey, Phoenix: Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1. in The Journal of clinical endocrinology and metabolism 2008
Human Polyclonal PGRMC1 Primary Antibody for WB - ABIN374668
Hand, Craven: Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 human breast cancer cells. in Journal of cellular biochemistry 2003
These results indicate that maintenance of Pgrmc1 signaling is required for Egfr (show EGFR Antibodies) expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr (show EGFR Antibodies) in maintaining meiotic arrest through estrogen activation of Gper (show GPER Antibodies).
Data suggest that PGRMC1 plays important roles in synthesis of cholesterol and steroids and in energy regulation. [REVIEW]
data illustrate a role for PGRMC1 in regulating heme synthesis via interactions with FECH (show FECH Antibodies) and suggest that PGRMC1 may be a heme chaperone or sensor
Demonstrate a change in myometriumPGRMC1 expression and changes in PGRMC1 and PGRMC2 (show PGRMC2 Antibodies) cell localisation in association with parturition.
The effects of progesterone treatment on the expression levels of progesterone receptor membrane component 1 (PGRMC1), plasminogen activator inhibitor 1 RNA-binding protein (PAIRBP1 (show SERBP1 Antibodies)), and progestin and adipoQ (show ADIPOQ Antibodies) receptor 7 (PAQR7 (show PAQR7 Antibodies)) on both mRNA and protein levels were investigated in spheroids derived from human glioma cell lines U-87 MG and LN-229.
It can be suggested that women with breast epithelium highly expressing PGRMC1 and in interaction with ERalpha (show ESR1 Antibodies) may have an increased risk to develop breast cancer.
These results clarify that PGRMC1 and the S2R are distinct binding sites expressed by different genes.
Haem-mediated PGRMC1 dimerization is required for interactions with EGFR (show EGFR Antibodies) and cytochromes P450 (show CYP2B6 Antibodies), cancer proliferation and chemoresistance against anti-cancer drugs.
indicate that PGRMC1 regulates hepcidin (show HAMP Antibodies) gene expression through an evolutionarily conserved mechanism
results suggested that PGRMC1 and sigma2 receptors are two different molecular entities.
PGRMC1 is the major progesterone receptor (show PGR Antibodies) eliciting the protective effects of Norgestrel, a synthetic female progesterone hormone.
PGRMC1 participates in late events of both mammalian mitosis and oocyte meiosis, consistent with PGRMC1's localization at the mid-zone and mid-body of the mitotic and meiotic spindle.
PGRMC1 protein expression and cellular distribution in cumulus cells
data indicate variable expression of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 mRNA and protein in bovine corpus luteum and suggest that progesterone may regulate corpus luteum function via its membrane receptors
Alterations in PGRMC1 and/or AURKB (show AURKB Antibodies) localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.
Data suggest that expression of PGRMC1 in bovine oviduct is primarily in luminal epithelium and is primarily cytoplasmic. Expression of PR (progesterone receptor (show PGR Antibodies)), PGRMC1, and PGRMC2 (show PGRMC2 Antibodies) are not affected by pregnancy or presence of corpus luteum.
analysis of expression of progesterone receptor membrane component 1, serpine mRNA binding protein 1 and nuclear progesterone receptor (show PGR Antibodies) isoforms A and B in the bovine myometrium during the estrous cycle and early pregnancy
With the exception of the corpora lutea, PGRMC1 localization showed similar pattern during different stages of the estrous cycle.
PGRMC1 is expressed in bovine oocytes and its localization changes at specific stages of oocyte maturation, which may be specifically related to the mechanism by which chromosomes segregate.
PGRMC1 mRNA is expressed in bovine CL and this expression varies throughout the luteal phase. It is assumed that PGRMC1 may be involved in a non-genomic effect of P(4) on luteal cells.
PGRMC1 expressed on the cell surface of beta cells was shown to interact with the activated GLP-1R (show GLP1R Antibodies) to enhance the insulinotropic actions of GLP-1 (show GCG Antibodies).
The aim of this study was to assess the expression, localization and hormonal regulation of two novel P(4) receptor candidates, P(4) receptor membrane component (PGRMC) 1 and PGRMC2 (show PGRMC2 Antibodies), as well as the PGRMC1 partner Serpine 1 (show SERPINE1 Antibodies) mRNA binding protein (SERBP1 (show SERBP1 Antibodies)).
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.
progesterone receptor membrane component 1
, membrane-associated progesterone receptor component 1
, progesterone binding protein
, steroid membrane binding protein
, acidic 25 kDa protein
, membrane-bound progesterone receptor
, ventral midline antigen