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Prokineticin 1 Proteins (Prok1)

The protein encoded by Prok1 induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Additionally we are shipping Prokineticin 1 Antibodies (66) and Prokineticin 1 Kits (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Prok1 84432 P58294
Prok1 246691 Q14A28
Prok1 192205 Q8R414
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Top Prokineticin 1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Mouse Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$367.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 4 to 6 Days
$412.50
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,132.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 8 Days
$185.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 11 Days
$545.60
Details

Prok1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,

Rat (Rattus)

More Proteins for Prokineticin 1 (Prok1) Interaction Partners

Cow (Bovine) Prokineticin 1 (Prok1) interaction partners

  1. important role for PK-1 in luteal function by acting as a mitogen and survival factor in corpus luteum derived endothelial cells

  2. PROK1, acting via PROKR1 (show PROKR1 Proteins), may be involved in the recruitment of monocytes to regressing CL

  3. EG-VEGF/PK1 and Bv8/PK2 (show PROK2 Proteins) thus represent new regulatory peptides acting as autocrine mitogens for endocrine cells

Human Prokineticin 1 (Prok1) interaction partners

  1. Results show the biological effects of PROK1-V67I on cell functions are similar to those of wild type, and the common variant of V67I may act as a modifier in the PROK1-PROKR system through down-regulation of PROK1 expression.

  2. Data suggest that prokineticins (PROK1 and PROK2 (show PROK2 Proteins)) and prokineticin receptors (PROKR1 (show PROKR1 Proteins) and PROKR2 (show PROKR2 Proteins)) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]

  3. EG-VEGF and its receptor PKR1 (show PROKR1 Proteins) might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.

  4. The prognosis was poorer in colorectal cancers that expressed both PROK1 and VEGF relative to the cases that expressed only 1 protein, and the expression of both proteins was found to be an independent prognostic factor.

  5. PROK1 levels in follicular fluid and fertilization culture media could constitute new predictive noninvasive markers of successful embryo implantation in conventional in vitro fertilization-embryo transfer

  6. Simultaneous targeting of both angiogenic growth factors (VEGF (show VEGFA Proteins)/PROK1) may prove more useful in colorectal cancer

  7. High Prokineticin 1 protein expression is associated with sporadic colorectal cancer.

  8. Expression of PROK1 and PROKR1 (show PROKR1 Proteins) was significantly higher in mid-gestation ovaries (17-20 wk) than at earlier gestations (8-11 and 14-16 wk).

  9. EG-VEGF, BV8 (show PROK2 Proteins), and PROKR2 (show PROKR2 Proteins) gene expression is approximately five, four, and two times higher in cystic fibrosis (show S100A8 Proteins) lungs compared with controls.

  10. More importantly this paper argues for EG-VEGF clinical relevance as a potential biomarker of the onset of pregnancy pathologies and discusses its potential usefulness for future therapeutic directions.

Mouse (Murine) Prokineticin 1 (Prok1) interaction partners

  1. EG-VEGF is a new mediator of PPARgamma (show PPARG Proteins) effects during pregnancy and bring new insights into the fine mechanism of trophoblast invasion.

  2. Bv8 (show PROK2 Proteins) and EG-VEGF, along with other factors such as VEGF-A (show VEGFA Proteins), may maintain the integrity and also regulate proliferation of the blood vessels in the testis

  3. This is the first report demonstrating that Prok-1 acts as a gut (show GUSB Proteins) mucosa/mesenchyme-derived factor and maintains proliferation and differentiation of enteric neural crest cells.

  4. EG-VEGF was mainly localised in the labyrinth in mouse placenta. It may have direct effect on both endothelial & trophoblastic cells & is likely to play an important role in mouse placentation.

  5. Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF (show GDNF Proteins)) to mediate proliferation and differentiation of enteric neural crest cells.

Prokineticin 1 (Prok1) Protein Profile

Protein Summary

The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

Gene names and symbols associated with Prokineticin 1 Proteins (Prok1)

  • prokineticin 1 (PROK1)
  • prokineticin 1 (prok1)
  • prokineticin 1 (LOC100358439)
  • prokineticin 1 (Prok1)
  • EG-VEGF protein
  • EGVEGF protein
  • PK1 protein
  • PRK1 protein
  • zgc:171925 protein

Protein level used designations for Prokineticin 1 Proteins (Prok1)

prokineticin 1 , prokineticin-1 , EG-VEGF , black mamba toxin-related protein , endocrine-gland-derived vascular endothelial growth factor , mambakine

GENE ID SPECIES
428257 Gallus gallus
490113 Canis lupus familiaris
617599 Bos taurus
701766 Macaca mulatta
745259 Pan troglodytes
100126018 Danio rerio
100358439 Oryctolagus cuniculus
100359362 Sus scrofa
84432 Homo sapiens
246691 Mus musculus
192205 Rattus norvegicus
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