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Proline Dehydrogenase (Oxidase) 1 Proteins (PRODH)

PRODH encodes a mitochondrial protein that catalyzes the first step in proline degradation. Additionally we are shipping PRODH Antibodies (75) and PRODH Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse PRODH PRODH 19125 Q9WU79
PRODH 5625 O43272
Rat PRODH PRODH 680409  
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Top PRODH Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days

PRODH Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Proline Dehydrogenase (Oxidase) 1 (PRODH) Interaction Partners

Arabidopsis thaliana Proline Dehydrogenase (Oxidase) 1 (PRODH) interaction partners

  1. ARR18 interaction negatively interferes with the transcriptional activity of bZIP63 on the PDH1 promoter. [PDH1]

  2. ProDH potentiates the oxidative burst and cell death associated with the hypersensitive response.

  3. ProDH-silenced plants displayed reduced ROS (show ROS1 Proteins) and cell death levels as well as enhanced susceptibility in response to avirulent pathogens.

  4. bZIP11 target processes are identified using transiently increased nuclear bZIP11 levels and genome-wide expression analysis; the effect of bZIP11 on ASN1 (show ASNS Proteins) and GBF6 are reported.

Mouse (Murine) Proline Dehydrogenase (Oxidase) 1 (PRODH) interaction partners

  1. PRODH/POX and succinate regulated mitochondrial respiration.

Human Proline Dehydrogenase (Oxidase) 1 (PRODH) interaction partners

  1. the frequency of a recurrent small 22q11.2 deletion encompassing PRODH and the neighboring DGCR6 (show DGCR6 Proteins) gene in three case-control studies, was studied.

  2. The findings support a major role for the PRODH 757TT, 1766GG, and 1852AA genotypes alone and in combination for schizophrenia susceptibility.

  3. Thirty-five percent of the subjects were hyperprolinemic, allele carriers of PRODH rs450046 had a lower full-scale intelligence compared to T allele carriers

  4. GR and KLF15 physically interact via low affinity GR binding sites within glucocorticoid response elements (GREs) for PRODH and AASS that contribute to combinatorial regulation with KLF15.

  5. results suggest that PRODH and COMT may interact to contribute to the ASD phenotype in individuals with VCFS

  6. Functional COMT (show COMT Proteins), but not PRODH, variant affects IQ and executive functions in 22q11.2DS subjects during neurodevelopment with a maximal effect at adulthood

  7. Data indicate that a functional proline dehydrogenase (PRODH) variant associated with schizophrenia that may have a neurochemical impact, altering brain function, but is not responsible for the cortical reductions found in the disorder.

  8. The current study demonstrates that sensory gating impairments that are typical of schizophrenia are found in 22q11.2DS subjects. Our results further suggest that COMT (show COMT Proteins) and PRODH genetic variations contribute to sensory gating.

  9. PRODH, but not PRODH2, expression is under the control of p53 (show TP53 Proteins) family members, specifically p53 (show TP53 Proteins) and p73 (show TP73 Proteins).

  10. Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH.

PRODH Protein Profile

Protein Summary

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PRODH

  • proline dehydrogenase (oxidase) 1 (PRODH)
  • proline dehydrogenase (oxidase) 1 (prodh)
  • proline dehydrogenase, mitochondrial (LOC411808)
  • Proline dehydrogenase (Proline oxidase) (SLGD_01166)
  • sluggish A (slgA)
  • proline dehydrogenase 1 (ERD5)
  • proline dehydrogenase (Prodh)
  • proline dehydrogenase (oxidase) 1 (Prodh)
  • AT-POX protein
  • ATPDH protein
  • ATPOX protein
  • CG1417 protein
  • Dmel\\CG1417 protein
  • EE85 protein
  • GB16218 protein
  • HSPOX2 protein
  • MGC115247 protein
  • PIG6 protein
  • POX protein
  • Pro-1 protein
  • Pro1 protein
  • PRODH protein
  • PRODH1 protein
  • PRODH2 protein
  • sl protein
  • slg protein
  • TP53I6 protein
  • tu3 protein
  • Ym24d07 protein

Protein level used designations for PRODH

proline dehydrogenase (oxidase) 1 , Proline dehydrogenase (Proline oxidase) , CG1417-PA , CG1417-PB , CG1417-PC , CG1417-PD , CG1417-PE , CG1417-PF , CG1417-PG , CG1417-PH , CG1417-PI , CG1417-PJ , CG1417-PK , CG1417-PL , CG1417-PM , CG1417-PN , proline dehydrogenase , slgA-PA , slgA-PB , slgA-PC , slgA-PD , slgA-PE , slgA-PF , slgA-PG , slgA-PH , slgA-PI , slgA-PJ , slgA-PK , slgA-PL , slgA-PM , slgA-PN , sluggish , sluggish-A , sluggishA , proline dehydrogenase, mitochondrial-like , proline dehydrogenase 1, mitochondrial , proline dehydrogenase, mitochondrial , proline oxidase , p53-induced gene 6 protein , proline oxidase 2 , proline oxidase, mitochondrial , tumor protein p53 inducible protein 6 , proline dehydrogenase (proline oxidase)

100050480 Equus caballus
734536 Xenopus laevis
411808 Apis mellifera
8818869 Staphylococcus lugdunensis HKU09-01
33117 Drosophila melanogaster
470141 Pan troglodytes
477562 Canis lupus familiaris
743147 Pan troglodytes
770734 Gallus gallus
822833 Arabidopsis thaliana
100455556 Pongo abelii
19125 Mus musculus
5625 Homo sapiens
680409 Rattus norvegicus
505094 Bos taurus
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