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Proline Rich Nuclear Receptor Coactivator 2 Proteins (PNRC2)

Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. Additionally we are shipping PNRC2 Antibodies (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PNRC2 55629 Q9NPJ4
PNRC2 52830 Q9CR73
PNRC2 100125373 Q66HE1
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Top PNRC2 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,286.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,297.17
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,302.67
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,324.67
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 56 to 66 Days
$2,348.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details

PNRC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) Interaction Partners

Human Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) interaction partners

  1. GR and PNRC2 interact in a ligand-dependent manner to recruit UPF1 (show UPF1 Proteins) for rapid mRNA degradation

  2. PNRC2 acts in synergy with Dcp1a (show DCP1A Proteins) to stimulate the decapping activity of Dcp2 (show DCP2 Proteins) by bridging the interaction between Dcp1a (show DCP1A Proteins) and Dcp2 (show DCP2 Proteins).

  3. Not only PNRC2 but also the corepressor TLE1 (show TLE1 Proteins) functioned as ERRgamma (show ESRRG Proteins) coactivator in a reporter gene analysis.

  4. PNRC2 plays an essential role in mammalian Nonsense-mediated mRNA decay (NMD), mediating the interaction between the NMD machinery and the decapping complex.

Mouse (Murine) Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) interaction partners

  1. The finding that the PNRC2 promoter is activated by NFY and repressed by E2F1 (show E2F1 Proteins) indicates that in addition to functioning as nuclear receptor coactivator, PNRC2 may also play a role in the cell cycle.

  2. Study provides evidence that PNRC2 plays one or more important roles in controlling the energy balance between energy storage and energy expenditure. PNRC2 may be a new target in the treatment of obesity and related metabolic diseases.

PNRC2 Protein Profile

Protein Summary

Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for upf1/rent1 localization to the P-body. Also acts as a nuclear receptor coactivator (By similarity).

Gene names and symbols associated with PNRC2

  • proline-rich nuclear receptor coactivator 2 (PNRC2)
  • proline-rich nuclear receptor coactivator 2 (Pnrc2)
  • proline-rich nuclear receptor coactivator 2 (pnrc2)
  • 0610011E17Rik protein
  • D4Bwg0593e protein
  • wu:cegs2777 protein
  • wu:fb51a04 protein
  • wu:fb81a06 protein
  • wu:fd19g06 protein

Protein level used designations for PNRC2

fb81a06

GENE ID SPECIES
55629 Homo sapiens
52830 Mus musculus
100125373 Rattus norvegicus
767836 Bos taurus
419688 Gallus gallus
100195218 Salmo salar
565522 Danio rerio
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