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Proline-, Glutamic Acid- and Leucine-Rich Protein 1 Proteins (PELP1)

PELP1 encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Additionally we are shipping PELP1 Antibodies (77) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PELP1 27043 Q8IZL8
Rat PELP1 PELP1 360552 Q56B11
PELP1 75273 Q9DBD5
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Top PELP1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details

PELP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) Interaction Partners

Human Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) interaction partners

  1. three techniques for the first time demonstrated the presence of the PELP1 in paraspinal muscles of patients with idiopathic scoliosis.

  2. PELP1 interacted with GR to activate Brk (show PTK6 Proteins) expression.

  3. we propose that PELP1/Ki-67 (show MKI67 Proteins) double high expression in tumors is an independent prognostic factor for predicting a poor outcome for patients with Triple-negative breast cancer

  4. There is mounting evidence that PELP1 plays key roles in several biological processes and its deregulation leads to the development of cancers.

  5. There are significantly higher amounts of PELP1 transcript and protein in tumor tissues in patients with non-small cell lung cancer.

  6. The diffuse and strong nuclear immunoreactivity of PELP1 in most cases suggests that PELP1 may be a molecular target for the treatment of triple-negative breast carcinoma

  7. Results show that PELP1 is highly phosphorylated in triple negative breast cancer cells and interacts with mutated Tp53 (show TP53 Proteins) and E2F1 (show E2F1 Proteins) to differentially regulates their target gene expression.

  8. The PELP1 interacts with p53 (show TP53 Proteins), functions as p53 (show TP53 Proteins)-coactivator and is required for optimal activation of p53 (show TP53 Proteins) target genes under genomic stress.

  9. unliganded PR-B (show PGR Proteins) enhanced proliferative responses to estradiol and IGF1 (show IGF1 Proteins) via scaffolding of ER-alpha (show ESR1 Proteins)/PELP1/IGF1R (show IGF1R Proteins)-containing complexes

  10. our data identified the PELP1-mTOR (show FRAP1 Proteins) axis as a novel component of PELP1 oncogenic functions and suggest that mTOR (show FRAP1 Proteins) inhibitor(s) will be effective chemotherapeutic agents for downregulating PELP1 oncogenic functions.

Rhesus Monkey Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) interaction partners

  1. MNAR/PELP1 is expressed and colocalizes with glucocorticoid receptors in monkey and rat brains.

Mouse (Murine) Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) interaction partners

  1. PELP1 is essential for the extranuclear signaling and neuroprotective actions of 17-beta estradiol in the hippocampal CA1 (show CA1 Proteins) region after global cerebral ischemia.

  2. These results further support the hypothesis that PELP1 deregulation has the potential to promote breast tumorigenesis in vivo and represent a novel model for future investigation into molecular mechanisms of PELP1-mediated tumorigenesis.

  3. PELP1 recruits HDAC2 (show HDAC2 Proteins) and masks histones using two separate domains

PELP1 Protein Profile

Protein Summary

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PELP1

  • proline, glutamate and leucine rich protein 1 (PELP1)
  • proline, glutamate and leucine rich protein 1 (Pelp1)
  • proline, glutamate and leucine rich protein 1 (pelp1)
  • proline, glutamic acid and leucine rich protein 1 (Pelp1)
  • 4930563C04Rik protein
  • MNAR protein
  • P160 protein
  • RGD1306320 protein

Protein level used designations for PELP1

proline, glutamate and leucine rich protein 1 , proline-, glutamic acid-, leucine-rich protein 1 , proline, glutamic acid and leucine rich protein 1 , proline, glutamic acid and leucine rich protein 1-like , modulator of non-genomic activity of estrogen receptor , proline and glutamic acid rich nuclear protein , proline-, glutamic acid- and leucine-rich protein 1 , transcription factor HMX3 , modulator of nongenomic activity of estrogen receptor , modulator of nongenomic actions of the estrogen receptor

GENE ID SPECIES
454449 Pan troglodytes
479475 Canis lupus familiaris
787413 Bos taurus
27043 Homo sapiens
360552 Rattus norvegicus
677854 Macaca mulatta
733329 Xenopus laevis
75273 Mus musculus
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