anti-Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) Antibodies

The protein encoded by PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. Additionally we are shipping PSTPIP1 Proteins (6) and PSTPIP1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PSTPIP1 9051 O43586
PSTPIP1 19200 P97814
PSTPIP1 300732  
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Top anti-PSTPIP1 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of STPIP1 / CD2BP1 Antibody (N-term) in K562 cell line lysates (35ug/lane). This demonstrates the PSTPIP1 antibody detected the PSTPIP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB PSTPIP1 Antibody (N-term) (ABIN656428) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the PSTPIP1 antibody detected the PSTPIP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using PSTPIP1 antibody. Immunohistochemistry of paraffin-embedded human gastric using PSTPIP1 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP1-85764] - Staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra. Western Blot: PSTPIP1 Antibody [NBP1-85764] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Chicken Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB PSTPIP1 monoclonal antibody (M02), clone 1D5. Western Blot analysis of PSTPIP1 expression in Raw 264.7. Detection limit for recombinant GST tagged PSTPIP1 is 1 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, FACS, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details

PSTPIP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)
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Rat (Rattus)


More Antibodies against PSTPIP1 Interaction Partners

Human Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) interaction partners

  1. HPIP expression is associated with high-grade ovarian tumors.

  2. we demonstrated that HPIP silencing suppressed TGF-beta1 (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) in lung cancer cells by inhibiting Smad2 (show SMAD2 Antibodies) activation.

  3. our study demonstrated that knockdown of HPIP significantly inhibits the proliferation and migration/invasion of HNSCC cells by suppressing the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

  4. these structural variations in CD2BP1 gene due to the mutations could be one of the strongest reasons to demonstrate the involvement of these gene variations in the patients with rheumatoid arthritis.

  5. PSTPIP1 was found to interact with pyrin (show MEFV Antibodies) at the leading edge during cell migration.

  6. Molecular interactions between HPIP and FAK (show PTK2 Antibodies), and HPIP and calpain2 regulate cell adhesion and migration through modulation of focal adhesion dynamics.

  7. Case Report: missense mutation in PSTPIP1, the gene responsible for PAPA (show PAPPA Antibodies) syndrome.

  8. we have shown that PSTPIP1 regulates T-cell activation upon CD3 and CD28 stimulation, independently of CD2 costimulation. PSTPIP1 acts downstream of proximal TCR signaling, inhibiting several transcription factors.

  9. PSTPIP1 has a role in the pathogenesis of pyoderma gangrenosum through filopodia formation resulting in extracellular matrix degradation

  10. novel mutaations found in PSTPIP1 gene in patients with pyoderma gangrenosum

Mouse (Murine) Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) interaction partners

  1. a new PSTPIP1/PTPN6 (show PTPN6 Antibodies)/SHIP1 (show INPP5D Antibodies)/2-dependent negative feedback mechanism that counterbalances Src (show SRC Antibodies) and PI(3,4,5)P3 signalling to control osteoclast cell polarity and activity during bone resorption

  2. analysis of inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA (show PAPPA Antibodies)) Syndrome-associated PSTPIP1 A230T mutant proteins

  3. the intracellular Fas ligand (FasL (show FASL Antibodies)) domain binding to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL (show FASL Antibodies)

  4. PSTPIP1 is a novel component of the leukocyte uropod that regulates endocytosis and cell migration

PSTPIP1 Antigen Profile

Protein Summary

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

Gene names and symbols associated with PSTPIP1

  • proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1) antibody
  • proline-serine-threonine phosphatase interacting protein 1 (pstpip1) antibody
  • proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1) antibody
  • CD2BP1 antibody
  • CD2BP1L antibody
  • CD2BP1S antibody
  • def-2 antibody
  • H-PIP antibody
  • PAPAS antibody
  • PSTPIP antibody
  • PSTPIP1 antibody

Protein level used designations for PSTPIP1

proline-serine-threonine phosphatase interacting protein 1 , proline-serine-threonine phosphatase-interacting protein 1 , CD2 antigen-binding protein 1 , CD2 cytoplasmic tail-binding protein , CD2-binding protein 1 , PEST phosphatase-interacting protein 1

GENE ID SPECIES
415349 Gallus gallus
447609 Xenopus laevis
513924 Bos taurus
100050881 Equus caballus
100152628 Sus scrofa
100379705 Xenopus (Silurana) tropicalis
9051 Homo sapiens
19200 Mus musculus
300732 Rattus norvegicus
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