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PTGER2 encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Additionally we are shipping PTGER2 Antibodies (107) and PTGER2 Proteins (5) and many more products for this protein.
Showing 10 out of 24 products:
Human PTGER2 ELISA Kit for Sandwich ELISA - ABIN417312
El-Ansary, Hassan, Qasem, Das: Identification of Biomarkers of Impaired Sensory Profiles among Autistic Patients. in PLoS ONE 2016
Prostaglandin E receptor subtype 2 (EP2 (show SPAG11A ELISA Kits); Ptger2) deficiency suppressed nuclear factor kappaB (NF-kappaB (show NFKB1 ELISA Kits)) activation in intracranial arteries 4 and 8 weeks after intracranial aneurysm induction.
neuronal EP2 receptor activation by PGE2 protects brain against intracerebral hemorrhage injury in middle-aged mice through its anti-inflammatory and anti-oxidant effects and anti-MMP-2 (show MMP2 ELISA Kits)/9 activity
data demonstrate that endogenous PGE2, EP2 (show SPAG11A ELISA Kits) receptors, and EPAC (show RAPGEF3 ELISA Kits) are prerequisites for maximal LPS (show TLR4 ELISA Kits)-induced IL-33 (show IL33 ELISA Kits) expression and that exogenous PGE2 can amplify IL-33 (show IL33 ELISA Kits) production via EP2 (show SPAG11A ELISA Kits) and EP4 (show PTGER4 ELISA Kits) receptors.
The data presented highlight a key role for EP2 (show SPAG11A ELISA Kits) and EP4 (show PTGER4 ELISA Kits) receptors in microvascular leak induced by PGE2.
Exposure of macrophages to cyclooxygenase (COX-2 (show COX2 ELISA Kits)) inhibitors RhoA (show RHOA ELISA Kits) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (show PTGDS ELISA Kits) receptors or the hepatocyte growth factor (HGF (show HGF ELISA Kits)) receptor c-Met (PHA (show LBR ELISA Kits)-665752), reversed EMT (show ITK ELISA Kits) inhibition by the conditioned medium
EP2 (show SPAG11A ELISA Kits) deficiency in MCs (show SMCP ELISA Kits) augmented TGF-beta1 (show TGFB1 ELISA Kits)-induced fibronectin (FN (show FN1 ELISA Kits)), cyclooxygenase-2 (COX2 (show PTGS2 ELISA Kits)), and CyclinD1 expression. Silencing of EP2 (show SPAG11A ELISA Kits) also strengthened TGF-beta1 (show TGFB1 ELISA Kits)-induced extracellular-signal-regulated kinase 1/2 (show MAPK3 ELISA Kits) (ERK1/2 (show MAPK1/3 ELISA Kits)) phosphorylation
autocrine prostaglandin E2 signaling through EP receptors is essential for optimal CD4 (show CD4 ELISA Kits)(+) T-cell activation.
the blockade of EP2 (show SPAG11A ELISA Kits) and EP4 (show PTGER4 ELISA Kits) promotes mouse survival after cryptococcus infection by promoting the production of cytokines via TLR4 (show TLR4 ELISA Kits), as well as the enhanced M1 polarization of alveolar macrophages
COX-2-derived PGE2 inhibits IL-10 expression in brain microglia through a novel EP2- and beta-arrestin-dependent signaling pathway.
Cardiac inflammation is reduced in EP-2 (show SPAG11A ELISA Kits)-/- mice.
in breast cancer cells overexpression of S1P3 (show S1PR3 ELISA Kits) and its activation by S1P (show MBTPS1 ELISA Kits) has pro-inflammatory and pro-metastatic potential by inducing COX-2 (show COX2 ELISA Kits) expression and PGE2 signaling via EP2 and EP4 (show PTGER4 ELISA Kits).
EP2 and EP3 (show PTGER3 ELISA Kits) receptors are involved in tolerance induction through IL-10 (show IL10 ELISA Kits) production by tol-DCs.
This is the first report that PGE2 -induced uPAR (show PLAUR ELISA Kits) expression, which stimulates invasiveness of human gastric cancer AGS (show JAG1 ELISA Kits) cells, is mediated by the EP2 receptor-dependent Src (show SRC ELISA Kits)/EGFR (show EGFR ELISA Kits)/JNK1 (show MAPK8 ELISA Kits)/2, Erk1/2 (show MAPK1/3 ELISA Kits)/AP-1 (show FOSB ELISA Kits), and Src (show SRC ELISA Kits)/EGFR (show EGFR ELISA Kits)/JNK1 (show MAPK8 ELISA Kits)/2, Erk1/2 (show MAPK1/3 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) cascades.
These results indicate that the ICL2 region of the EP2 receptor is its potential interaction site with Galphas (show GNAS ELISA Kits), and that the aromatic side chain moiety at position 143 is a determinant for the accessibility of the ICL2 to the Galphas (show GNAS ELISA Kits) protein.
EP2 receptors seem to be able to distinguish endogenous ligands PGD2 (show PTGDS ELISA Kits), PGE2 or prostaglandin F2alpha better than DP receptors.
EP2 receptor activation protects against endoplasmic reticulum stress-dependent mitochondrial apoptosis through down-regulation of p53 (show TP53 ELISA Kits).
that the expression of ERG (show ERG ELISA Kits) in prostate cancer is linked to the expression of IL-6 (show IL6 ELISA Kits) mediated by the prostanoid receptor EP2
mPGES-1 (show PTGES ELISA Kits) is downregulated via EGR1 (show EGR1 ELISA Kits) and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes
Altered expression of EP2 in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (show IL1B ELISA Kits) to increase COX-2 (show COX2 ELISA Kits) and mPGES-1 (show PTGES ELISA Kits) expression, which results in low PGE2 production
Reduced EP2 receptor expression results in resistance to the antiproliferative effects of EP2 signaling in nasal polyp fibroblasts from subjects with AERD and support a role for EP2 signaling in the aberrant growth of nasal polyp tissue.
Data suggest that lysophosphatidic acid (LPA (show PLG ELISA Kits)) up-regulates expression of SLCO2A1 (show SLCO2A1 ELISA Kits) (prostaglandin [PG] transporter), PTGER2/PTGER4 (show PTGER4 ELISA Kits) (PG receptors EP2 (show SPAG11A ELISA Kits)/EP4 (show PTGER4 ELISA Kits)), and mPGES1 (show PTGES ELISA Kits)/cPGES (show PTGES3 ELISA Kits) (microsomal/cytosolic PG E synthases) in luteal cells.
Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (prostaglandin E receptor 2); EP4/PTGER4 (show PTGER4 ELISA Kits) (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor (show PTGFR ELISA Kits)).
EP2 (show SPAG11A ELISA Kits) is the major cAMP-generating PGE (show LIPF ELISA Kits)(2) receptor expressed and regulated in the bovine uterus during the estrous cycle and early pregnancy.
COX-2 (show PTGS2 ELISA Kits) and FP receptor (show PTGFR ELISA Kits) contribute via changes in amount and distribution to mechanisms associated with parturition.
Quantitative RT-PCR revealed significant higher expression of EP2 (show SPAG11A ELISA Kits) and EP4 (show PTGER4 ELISA Kits) in the pre-ovulatory phase compared with the luteal phase in the bovine oviduct
This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.
, prostaglandin E receptor 2 (subtype EP2), 53kDa
, prostaglandin E2 receptor EP2 subtype
, EP2 receptor
, PGE receptor EP2 subtype
, PGE2 receptor EP2 subtype
, prostaglandin E receptor 2 (EP2 subtype)
, prostaglandin E receptor EP2 subtype
, prostaglandin E receptor subtype EP2
, prostanoid EP2 receptor
, PGE receptor, EP2 subtype
, prostaglandin E2 receptor type 2
, prostaglandin E2 receptor subtype EP2