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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Proteins (PSMD10)

PSMD10 encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. Additionally we are shipping Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Antibodies (83) and Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSMD10 5716 O75832
PSMD10 53380 Q9Z2X2
Rat PSMD10 PSMD10 116722 Q9Z2X3
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Top Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Proteins at antibodies-online.com

Showing 8 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 Days
$385.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

PSMD10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Top referenced Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Proteins

  1. Human PSMD10 Protein expressed in Escherichia coli (E. coli) - ABIN667086 : Chen, Li, Fu, Wang, Ren, Dong, Tang, Liu, Wu, Wang: Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the cytoplasm through nuclear export. in Cell research 2007 (PubMed)
    Show all 2 references for ABIN667086

More Proteins for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) Interaction Partners

Zebrafish Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. This study is the first to report gankyrin as a potential link between microRNAs and liver steatosis in zebrafish.

Human Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. Gankyrin-overexpressed non-small cell lung cancer patients had a significantly shorter survival time

  2. Results identified rs111638916 SNP in the PSMD10 3'-UTR as a risk factor for gastric cancer (GC) and acted as a tumor promoting factor. SNP rs111638916 was also regulated by miR (show MLXIP Proteins)-505, resulting in its up-regulation in patients with GA and AA genotypes.

  3. p28GANK expression was increased in metastatic ESCC tissues and cells, and p28GANK knockdown decreased the metastatic ability of ESCC cells.

  4. This study identifies gankyrin, for the first time, as new potential predictive and oncogenic factor of well-differentiated/dedifferentiated liposarcoma, suggesting the potential for service as a future Liposarcoma therapeutic approach.

  5. On the base results of present study one can suggests the p28GANK being useful as a predictive marker for patient prognosis and a novel therapeutic target for gastric cancer.

  6. IL-1beta (show IL1B Proteins) stimulation causes sequential phosphorylation of IRAK-1 (show IRAK1 Proteins), c-Jun N-terminal kinase, and p300 (show EP300 Proteins) and enhances recruitment of the p300/CBP (show CREBBP Proteins)/NF-Y complex to Gankyrin promoter

  7. Gankyrin is aberrantly expressed beginning at the initiation stage and plays an important role in the initiation, promotion, and progression of hepatocarcinogenesis.

  8. Gankyrin may be functional in cervical carcinogenesis and metastasis.

  9. MiR (show MLXIP Proteins)-605 directly targets and represses PSMD10 expression.

  10. The intensity of gankyrin expression was 'positive' in two cases (20%) and 'strongly positive' in eight cases (80%).

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. the present study clarified, at least partly, mechanisms of vascular tumorigenesis, and suggests that gankyrin might play a physiological role in hypoxic responses besides its roles as an oncoprotein.

  2. FXR (show NR1H4 Proteins) prevents liver cancer by inhibiting the gankyrin promoter via C/EBPbeta (show CEBPB Proteins)-HDAC1 (show HDAC1 Proteins) complexes, leading to subsequent protection of tumor suppressor proteins from degradation.

  3. Gankyrin is a key regulator of Ras-mediated activation of Akt through inhibition of the downstream RhoA/ROCK pathway and thus plays an essential role in Ras-induced tumorigenesis.

  4. Findings suggest that retinoblastoma protein degradation in Lmna (show LMNA Proteins)-/- cells occurs by gankyrin and MDM2 (show MDM2 Proteins)-independent mechanisms.

  5. Gankyrin oncoprotein has a role in progression of esophageal squamous cell carcinoma

Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) Protein Profile

Protein Summary

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Gene names and symbols associated with PSMD10

  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (psmd10)
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (PSMD10)
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (Psmd10)
  • AW554874 protein
  • dJ889N15.2 protein
  • gankyrin protein
  • p28 protein
  • p28(GANK) protein
  • p28Gank protein
  • zgc:109707 protein

Protein level used designations for PSMD10

26S proteasome non-ATPase regulatory subunit 10 , gank , proteasome 26S subunit, non-ATPase, 10 , 26S proteasome regulatory subunit p28 , ankyrin repeat protein , gankyrin , hepatocellular carcinoma-associated protein p28-II , proteasome subunit p28 , proteosome (prosome, macropain) 26S subunit, non-ATPase, 10 , proteosome subunit p28 , proteasome 26S non-ATPase subunit 10

GENE ID SPECIES
403085 Danio rerio
5716 Homo sapiens
53380 Mus musculus
116722 Rattus norvegicus
481014 Canis lupus familiaris
535414 Bos taurus
100724287 Cavia porcellus
101113657 Ovis aries
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