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May play a role in vesicle formation and transport (By similarity).. Additionally we are shipping PACSIN1 Antibodies (75) and PACSIN1 Proteins (7) and many more products for this protein.
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Specifically, CKS1B (show CKS1B ELISA Kits) and MAP2K5 (show MAP2K5 ELISA Kits) significantly inhibited hepatitis C viral RNA replication. PACSIN1, by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.
syndapin I functions reflected direct, SH3 domain (show ITSN1 ELISA Kits)-mediated associations and functional interactions with ProSAP1/Shank2 (show SHANK2 ELISA Kits).
Data indicate that the structural capacity of N17 to fold back toward distal regions within huntingtin (show HTT ELISA Kits) requires an interacting protein, protein kinase C (show PKC ELISA Kits) and casein kinase 2 substrate in neurons 1 (PACSIN1).
Pacsin-1 plays a versatile role in sculpting cellular membranes that is likely dependent both on protein structure and membrane properties.
PACSIN1 represents a pDC (show PNKD ELISA Kits)-specific adaptor molecule that plays an important role in the TLR7 (show TLR7 ELISA Kits)/9-mediated type I IFN responses by pDCs in vitro and in vivo.
Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation
PACSIN 1 (1-344) was crystallized & diffracted to resolution of 3.0 A. The crystal belonged to space group C2, with unit-cell parameters a=158.65, b=87.38, c=91.76 A, alpha=90.00, beta=113.61, gamma=90.00 degrees. There are 2 molecules in asymmetric unit.
The SdpI-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.
upon BDNF (show BDNF ELISA Kits) signaling PACSIN 1 is phosphorylated by CK2 (show CSNK2A1 ELISA Kits) which is essential for spine formation
PACSIN1 is an important Tau binding partner in regulating microtubule dynamics and forming axonal plasticity.
These results implicate Pak5 (show PAK7 ELISA Kits) in Pacsin1- and Synaptojanin1-mediated synaptic vesicle trafficking.
syndapin I acts as pivotal membrane anchoring factor for dynamins during regeneration of synaptic vesicles.
May play a role in vesicle formation and transport (By similarity).
protein kinase C and casein kinase substrate in neurons 1
, protein kinase C and casein kinase substrate in neurons 2
, protein kinase C and casein kinase substrate in neurons protein 1
, syndapin 1
, syndapin I
, Syndapin I
, dynamin PRD-interacting protein
, dynamin proline-rich domain-interacting protein
, synaptic, dynamin-associated protein I