You are viewing an incomplete version of our website. Please click to reload the website as full version.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Proteins (PPP1R1B)

PPP1R1B encodes a bifunctional signal transduction molecule. Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Antibodies (174) and Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP1R1B 360616 Q6J4I0
PPP1R1B 84152 Q9UD71
PPP1R1B 19049 Q60829
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,289.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,491.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,500.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PPP1R1B Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,
Mouse (Murine)

More Proteins for Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) Interaction Partners

Rhesus Monkey Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. DARPP-32 and I-1 were most frequently identified in dendritic shafts, unlike the D1R (show DRD1 Proteins) and PP1 (show PPYR1 Proteins) isoforms. Moreover, DARPP-32 and I-1 were only present in approximately 4% and 8% of area 9 pyramidal cell spines, respectively.

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. DARPP-32 is mainly cleaved at Thr (show TRH Proteins)(153) by calpain and this cleavage of DARPP-32 reduces CREB (show CREB1 Proteins) phosphorylation via loss of its inhibitory function on PP1 (show PPA1 Proteins); results suggest a novel mechanism of DARPP-32-CREB (show CREB1 Proteins) signalling dysregulation in Alzheimer's disease

  2. No significant differences in mRNA expression levels of DRD2 (show DRD2 Proteins) and DARPP-32 were found among controls, patients with psychotic disorder not otherwise specified, and schizophrenia/schizophreniform disorder.

  3. Striatal function was indexed by a gene coding for DARPP-32, which is densely expressed in the striatum where it is necessary for synaptic plasticity

  4. Findings show that PPP1R1B-STARD3 (show STARD3 Proteins) fusion transcript has a key role in subsets of gastric cancers through the activation of PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling.

  5. Results suggest that variation in PPP1R1B affects the abundance of the splice variant t-DARPP-32 mRNA and may reflect potential molecular mechanisms implicated in schizophrenia and affective disorders

  6. The immunostaining was more decreased for DARPP-32 than for the morphological changes of striatal neurons in multiple system atrophy.

  7. This study showed that variations in genotypes relevant for DARPP-32 functions are associated more with aging-related impairments in the explicit than the implicit component of sequence learning.

  8. density of DARPP-32-immunoreactive (IR) neurons in the II and III layers of the RAIC was significantly decreased (p<0.05) in the schizophrenia group compared with the healthy control group.

  9. Bcl-2 (show BCL2 Proteins) and DARPP-32 have roles in regulating inositol 1,4,5-trisphosphate receptor phosphorylation and promoting cell survival

  10. High DARPP32/STAT3 (show STAT3 Proteins), DARPP32/STAT5B (show STAT5B Proteins), and STAT5B (show STAT5B Proteins)/STAT3 (show STAT3 Proteins) ratios were associated with longer patient progression free survival.

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. Darpp32 interaction with beta-adducin (show ADD2 Proteins) may be the molecular pathway by which environmental changes may rapidly alter responsiveness of striatal neurons involved in the reward system.

  2. Results show that Darpp-32 was expressed in normal mouse mammary tissue and in some breast tumors, whereas t-Darpp was found exclusively in mammry tumors.

  3. analysis of cAMP-activated DARPP-32 signalling to the nucleus

  4. Results describe the development of new vascular mouse model with a conditional knockout allele of Tsc1 (show TSC1 Proteins) with a Darpp32-Cre allele. This mouse displayed accelerated formation of both kidney cystadenomas and paw hemangiosarcomas.

  5. Cannabinoid-stimulated G-protein activity did not differ between DARPP-32 KO and WT mice treated with vehicle or repeated THC.

  6. In this work, the dissected postsynaptic topology of the DARPP-32 phosphoprotein provides strong evidence for a compartmentalized and confined distribution in dendritic spines.

  7. Adenosine AA receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.

  8. Data suggest that histone deacetylase (show HDAC1 Proteins) inhibitors inhibit the induction of NGF1A-binding protein (show NAB1 Proteins) Nab2 (show NAB2 Proteins) by brain derived neurotrophic factor (BDNF (show BDNF Proteins)), and thereby the relative induction of dopamine and cyclic AMP-regulated phosphoprotein (show ARPP21 Proteins), 32 kDa (DARPP-32).

  9. This study demonistrated that environment enhanced Darpp32 expression in brain and enhanced totaroad perfermance and short term working menory.

  10. DARPP32 has a role in pluripotent stem cell differentiation toward medium-sized spiny neurons

Xenopus laevis Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. Areas of brain and spinal cord that are densely innervated by tyrosine hydroxylase (show TH Proteins)-immunoreactive fibers display a remarkable immunoreactivity for DARPP-32/ppp1r1b in cell bodies and neuropil.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) Protein Profile

Protein Summary

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PPP1R1B

  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (ppp1r1b)
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (PPP1R1B)
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (LOC100355399)
  • protein phosphatase 1 regulatory subunit 1B-like (LOC100736966)
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (Ppp1r1b)
  • AU040756 protein
  • DARPP-32 protein
  • DARPP32 protein

Protein level used designations for PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) , neuronal phosphoprotein DARPP-32 , protein phosphatase 1 regulatory subunit 1B , protein phosphatase 1, regulatory (inhibitor) subunit 1B , dopamine- and cAMP-regulated neuronal phosphoprotein , dopamine- and cAMP-regulated phosphoprotein DARPP-32 , dopamine and cAMP-regulated neuronal phosphoprotein 32 , DARPP-32 , dopamine and cAMP regulated

GENE ID SPECIES
100124928 Xenopus (Silurana) tropicalis
574203 Macaca mulatta
608394 Canis lupus familiaris
744755 Pan troglodytes
100355399 Oryctolagus cuniculus
100736966 Sus scrofa
360616 Rattus norvegicus
84152 Homo sapiens
19049 Mus musculus
733416 Xenopus laevis
282459 Bos taurus
Selected quality suppliers for Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Proteins (PPP1R1B)
Did you look for something else?