Protein Phosphatase 5, Catalytic Subunit Proteins (PPP5C)

PPP5C encodes a member of the Kunitz-type serine proteinase inhibitor family. Additionally we are shipping Protein Phosphatase 5, Catalytic Subunit Antibodies (162) and Protein Phosphatase 5, Catalytic Subunit Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP5C 5536 P53041
PPP5C 19060 Q60676
PPP5C 65179 P53042
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Top Protein Phosphatase 5, Catalytic Subunit Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days
$1,994.67
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,411.83
Details

PPP5C Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Protein Phosphatase 5, Catalytic Subunit Proteins

  1. Human PPP5C Protein expressed in Wheat germ - ABIN1316089 : Horibe, Kohno, Haramoto, Ohara, Kawakami: Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent. in Journal of translational medicine 2011 (PubMed)

More Proteins for Protein Phosphatase 5, Catalytic Subunit (PPP5C) Interaction Partners

Human Protein Phosphatase 5, Catalytic Subunit (PPP5C) interaction partners

  1. Our results showed 1) a critical role for PP5 in cytokine-induced resistance to GC-mediated eosinophil death, 2) supported the dependence of GCR (show NR3C1 Proteins) phosphorylation on PP5 activity, and 3) revealed that PP5 is a target of the lipoxin A4-induced pathway countering cytokine-induced resistance to GCs (show GCLC Proteins) in eosinophils.

  2. our research indicated that miR (show MLXIP Proteins)-130a functions as an oncogene (show RAB1A Proteins) by targeting TFPI2 (show TFPI2 Proteins), miR (show MLXIP Proteins)-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK (show PTK2 Proteins)/PI3K (show PIK3CA Proteins)/Rac1/mdm2 (show MDM2 Proteins) pathway

  3. TFPI-2 (show TFPI2 Proteins) expression was decreased in bladder cancer. TFPI-2 (show TFPI2 Proteins) expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.

  4. TFPI2 (show TFPI2 Proteins) is a useful serum biomarker for preoperative clinical diagnosis of CCC.

  5. This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.

  6. Over-expression of TFPI-2 (show TFPI2 Proteins) and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.

  7. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Proteins) accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Proteins)) in the matrix.

  8. the importance of PP5 in CRC (show CALR Proteins) cell growth

  9. PPP5C could be essential for glioma cell growth.

  10. Hypermethylation of TFPI2 (show TFPI2 Proteins) promoter is increased in inflamed colon tissue.

Mouse (Murine) Protein Phosphatase 5, Catalytic Subunit (PPP5C) interaction partners

  1. PP5 is a unique phosphatase reciprocally regulating PPARgamma (show PPARG Proteins) and RUNX2 (show RUNX2 Proteins) activities in marrow mesenchymal stem cell

  2. Mice with inactivated protein phosphatase 5 have decreased adipogenesis.

  3. Ppp5c- knockout mice are resistant to weight gain induced by high fat diet.

  4. Chp-1 (show CHORDC1 Proteins) and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 and Sgt1 (show SUGT1 Proteins) and with each other in an ATP-dependent manner

  5. PP5 regulates the TGFbeta (show TGFB1 Proteins) pathway in MEFs by regulating the expression of SMAD3 (show SMAD3 Proteins) protein levels.

  6. Data show that protein phosphatase 5 (PP5), a nuclear receptor co-chaperone, reciprocally modulates the lipometabolic activities of GRalpha and PPARgamma.

  7. genetic disruption of PP5 is associated with enhanced and prolonged phosphorylation of a single serine (Ser (show SIGLEC1 Proteins)-345) on Chk1 (show CHEK1 Proteins)

  8. Constitutive over expression of serine/threonine protein phosphatase 5 augments estrogen-dependent tumor growth in mice

  9. tau is probably a physiological substrate of protein phosphatase 5 (PP5) and that the abnormal hyperphosphorylation of tau in Alzheimer disease might result in part from the decreased PP5 activity in the diseased brains

  10. Data suggest that endogenous protein phosphatase 5 can exert a negative modulatory effect on basal ACTH (show POMC Proteins) release in neurosecretion-competent AtT20 cells.

Protein Phosphatase 5, Catalytic Subunit (PPP5C) Protein Profile

Protein Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PPP5C

  • protein phosphatase 5, catalytic subunit (ppp5c)
  • protein phosphatase 5, catalytic subunit (PPP5C)
  • protein phosphatase 5, catalytic subunit (Ppp5c)
  • tissue factor pathway inhibitor 2 (TFPI2)
  • AU020526 protein
  • fc83f08 protein
  • im:7146608 protein
  • MGC89961 protein
  • PP5 protein
  • PPP5 protein
  • PPP5C protein
  • PPT protein
  • REF1 protein
  • TFPI-2 protein
  • wu:fc83f08 protein
  • zgc:110801 protein

Protein level used designations for PPP5C

serine/threonine-protein phosphatase 5 , protein phosphatase 5, catalytic subunit , serine/threonine-protein phosphatase 5-like , PP-T , protein phosphatase T , ANP receptor , PPT , PP5 , placental protein 5 , retinal pigment epithelium cell factor 1

GENE ID SPECIES
398004 Xenopus laevis
456150 Pan troglodytes
493275 Xenopus (Silurana) tropicalis
510245 Bos taurus
541536 Danio rerio
592155 Strongylocentrotus purpuratus
612199 Canis lupus familiaris
716214 Macaca mulatta
100174541 Pongo abelii
100414496 Callithrix jacchus
100513542 Sus scrofa
100564151 Anolis carolinensis
100583672 Nomascus leucogenys
100186268 Ciona intestinalis
100208775 Hydra magnipapillata
100472775 Ailuropoda melanoleuca
5536 Homo sapiens
19060 Mus musculus
65179 Rattus norvegicus
7980 Homo sapiens
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