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Protein Phosphatase Methylesterase 1 (PPME1) ELISA Kits

Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA; MIM 176915) (Ogris et al., 1999. Additionally we are shipping Protein Phosphatase Methylesterase 1 Antibodies (53) and Protein Phosphatase Methylesterase 1 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PPME1 51400 Q9Y570
PPME1 72590 Q8BVQ5
PPME1 361613 Q4FZT2
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Top Protein Phosphatase Methylesterase 1 ELISA Kits at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 0.625-40 ng/mL 96 Tests Log in to see 11 to 13 Days
$1,029.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Human
96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for Protein Phosphatase Methylesterase 1 Interaction Partners

Human Protein Phosphatase Methylesterase 1 (PPME1) interaction partners

  1. LCMT1 (show LCMT1 ELISA Kits)-PME-1 methylation equilibrium is critical for regulating mitotic spindle size and thereby proper cell division

  2. this study suggests that the tightly linked regulatory loop comprised of the SIK2 (show SIK2 ELISA Kits)-PP2A (show PPP2R4 ELISA Kits) and CaMKI (show CAMK1 ELISA Kits) and PME-1 networks may function in fine-tuning cell proliferation and stress response.

  3. PPME1 could be an attractive therapeutic target for a subset of gastric cancer and lung cancer.

  4. Data indicate that PP2A (show PPP2R4 ELISA Kits) holoenzyme biogenesis and activity are controlled by five PP2A (show PPP2R4 ELISA Kits) modulators, consisting of alpha4, PTPA (show PPP2R4 ELISA Kits), LCMT1 (show LCMT1 ELISA Kits), PME-1 and TIPRL1, which serve to prevent promiscuous phosphatase activity until the holoenzyme is completely assembled.

  5. GSK-3beta can inhibit PP2A (show PPP2R4 ELISA Kits) by increasing the inhibitory L309-demethylation involving upregulation of PME-1 and inhibition of PPMT1 (show LCMT1 ELISA Kits)

  6. Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors.

  7. We propose that stabilization of this inactive, nuclear PP2A (show PPP2R4 ELISA Kits) pool is a major in vivo function of PME-1.

  8. Observations identify PME-1 expression as one mechanism by which ERK (show EPHB2 ELISA Kits) pathway activity is maintained in cancer cells and suggest an important functional role for PME-1 in the disease progression of human astrocytic gliomas.

Mouse (Murine) Protein Phosphatase Methylesterase 1 (PPME1) interaction partners

  1. protects protein phosphatase 2A from ubiquitin/proteasome degradation

  2. Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors.

  3. PME-1 plays a critical role in differentiation of neuroblastoma (show ARHGEF16 ELISA Kits) cells.

  4. targeted disruption of the PME-1 gene causes perinatal lethality in mice, a phenotype that correlates with a virtually complete loss of the demethylated form of PP2A in the nervous system and peripheral tissues

Protein Phosphatase Methylesterase 1 (PPME1) Antigen Profile

Antigen Summary

This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PPME1

  • protein phosphatase methylesterase 1 (ppme1) antibody
  • esterase/lipase/thioesterase family protein (AT4G10050) antibody
  • protein phosphatase methylesterase 1 (LOC100358403) antibody
  • protein phosphatase methylesterase 1 (PPME1) antibody
  • protein phosphatase methylesterase 1 (Ppme1) antibody
  • similar to S. cerevisiae PPE1 (YHR075C) mitochondrial ribosome small subunit protein YMS2, which resembles a phosphatase-methylesterase (PPE1) antibody
  • 1110069N17Rik antibody
  • 2700017M01Rik antibody
  • DDBDRAFT_0204584 antibody
  • DDBDRAFT_0305014 antibody
  • DDB_0204584 antibody
  • DDB_0305014 antibody
  • F28M11.4 antibody
  • fk72d03 antibody
  • PME-1 antibody
  • PME1 antibody
  • PME1MGC133824 antibody
  • RGD1309683 antibody
  • wu:fk72d03 antibody
  • zgc:56239 antibody

Protein level used designations for PPME1

protein phosphatase methylesterase 1 , phosphatase methylesterase 1 , protein phosphatase methylesterase-1 , PME-1 , likely mitochondrial ribosomal protein (YMS2)

GENE ID SPECIES
335124 Danio rerio
826596 Arabidopsis thaliana
8623168 Dictyostelium discoideum AX4
100195184 Salmo salar
100358403 Oryctolagus cuniculus
446717 Xenopus laevis
419058 Gallus gallus
51400 Homo sapiens
612812 Canis lupus familiaris
535390 Bos taurus
72590 Mus musculus
361613 Rattus norvegicus
100173996 Pongo abelii
3635974 Candida albicans SC5314
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