Protocadherin 19 Proteins (PCDH19)

The protein encoded by PCDH19 is a member of the delta-2 protocadherin subclass of the cadherin superfamily. Additionally we are shipping Protocadherin 19 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCDH19 57526 Q8TAB3
PCDH19 279653 Q80TF3
Rat PCDH19 PCDH19 317183  
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Top Protocadherin 19 Proteins at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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HOST_Wheat germ Human GST tag   25 μg Log in to see 11 to 12 Days
$460.60
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PCDH19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,

More Proteins for Protocadherin 19 (PCDH19) Interaction Partners

Human Protocadherin 19 (PCDH19) interaction partners

  1. This is the second male with somatic mosaicism for PCDH19 deficiency, providing further support for cellular interference as the pathogenic mechanism for this condition, which leads to this unusual mode of inheritance in which females are more severely affected than males.

  2. Our results show a large spectrum of intellectual disability and a very high rate of Autism spectrum disorder in patients with epilepsy and PCDH-19 mutations

  3. These findings point to multiple defects in peripheral steroidogenesis associated with and potentially relevant to PCDH19-FE. Some of these defects could be addressed by stimulating adrenocortical activity.

  4. Results summarized the clinical spectrum of female epilepsy patients with protocadherin 19 (PCDH19) mutations in a Chinese population.

  5. mild tonic, fluttering and mild clonic phases were most characteristic of seizures of PCDH19-related epilepsy

  6. The study demonistrated that most effective drugs in patients with PCDH19 mutations were bromide and clobazam.

  7. PCDH19 has a role in instructing the apico-basal polarity of the progenitor cells, thus regulating the development of a properly organized human brain

  8. Two mosaic PCDH19 point mutations are described in male patients with PCDH19-related epilepsy.

  9. steroids and in particular neurosteroids (e.g. allopregnanolone) play an important role in PCDH19-FE and represent a realistic therapeutic target.

  10. This case report is suggestive of a good response of PCDH19-related Epilepsy to stiripentol

Mouse (Murine) Protocadherin 19 (PCDH19) interaction partners

  1. Pcdh19 gene is developmentally regulated during mouse organogenesis and shows a unique expression profile among protocadherins.

Protocadherin 19 (PCDH19) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Protocadherin 19 Proteins (PCDH19)

  • protocadherin 19 (PCDH19)
  • protocadherin 19 (Pcdh19)
  • B530002L05Rik protein
  • EFMR protein
  • EIEE9 protein
  • Gm717 protein
  • mKIAA1313 protein
  • RGD1565392 protein

Protein level used designations for Protocadherin 19 Proteins (PCDH19)

protocadherin-19

GENE ID SPECIES
57526 Homo sapiens
279653 Mus musculus
317183 Rattus norvegicus
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