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Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Proteins (P2RX3)

The product of P2RX3 belongs to the family of purinoceptors for ATP. Additionally we are shipping Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat P2RX3 P2RX3 81739 P49654
P2RX3 5024 P56373
P2RX3 228139 Q3UR32
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Top Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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P2RX3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Interaction Partners

Human Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) interaction partners

  1. Data indicate P2X3 purinergic receptors as potential new targets for hepatocellular carcinoma (HCC (show FAM126A Proteins)) therapy.

  2. Results demonstrate that the stoichiometry of the heterotrimeric hP2X2/3 receptor is not fixed, but determined by the relative availability of P2X2 (show P2RX2 Proteins) and P2X3 subunits

  3. Urothelial P2X3 receptors decreased significantly in responders after Lipotoxin instillation, but not after BoNT-A injection.

  4. The results from this study demonstrate that there is a significant difference in the expression of the purinergic P2X2 (show P2RX2 Proteins), P2X3 and P2X7 (show P2RX7 Proteins) receptors in the different histological layers of the human urinary bladder.

  5. sensory proteins P2X3 and TRPV1 (show TRPV1 Proteins) are in correlation with urothelial differentiation, while P2X5 (show P2RX5 Proteins) and TRPV4 (show TRPV4 Proteins) have unique expression patterns

  6. esophagitis increases mRNA expressions of P2X3 and P2X7 (show P2RX7 Proteins) receptors accompanied by up-regulation of TRPV1 (show TRPV1 Proteins) and neurotrophic factors (NGF (show NGFB Proteins) and GDNF (show GDNF Proteins)).

  7. Conformational flexibility of the agonist binding jaw of the human P2X3 receptor is a prerequisite for channel opening

  8. TRPV1 (show TRPV1 Proteins)-, TRPV2 (show TRPV2 Proteins)-, P2X3-, and parvalbumin (show PVALB Proteins)-immunoreactivity neurons in the human nodose ganglion innervate the pharynx and epiglottis through the pharyngeal branch and superior laryngeal nerve

  9. ATP-gated P2X3 channels in enterochromaffin cells are downregulated in ulcerative colitis.

  10. Data indicate that MgATP2- activates P2X1 (show P2RX1 Proteins) and P2X3, but not P2X2 (show P2RX2 Proteins) and P2X4 (show P2RX4 Proteins) receptors.

Mouse (Murine) Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) interaction partners

  1. mouse trigeminal neurons endogenous BNP acts on NPR-A (show NPR1 Proteins) receptors to determine constitutive depression of P2X3 receptor function. Tonic inhibition of P2X3 receptor activity by BNP/NPR-A (show NPR1 Proteins)/PKG (show PRKG1 Proteins) pathways occurs via two distinct mechanisms: P2X3 serine phosphorylation and receptor redistribution to non-raft membrane compartments

  2. This study observed maltodextrin and fat preference deficits in "taste-blind" P2X2 (show P2RX2 Proteins)/P2X3 knockout mice.

  3. a slow modulatory action by BNP on TRPV1 (show TRPV1 Proteins) and P2X3 receptors outlining the role of this peptide as a negative regulator of trigeminal sensory neuron excitability to nociceptive stimuli

  4. P2X(3)R overexpression may underlie ectopic mechanical allodynia in the whisker pad skin

  5. genetic manipulation of TRPV1 (show TRPV1 Proteins) and P2X3 leads to reduction in colorectal mechanosensation peripherally and compensatory changes and/or disinhibition of other channels centrally.

  6. up-regulation of P2X3 receptors probably is already maximal and is apparently contributed by basal CGRP (show CALCA Proteins) and BDNF (show BDNF Proteins) levels

  7. Structure and function of P2RX3 is reviewed, and its role in treatment of pain is discussed. [Review Article]

  8. interaction between P2X3/TRPV1 and ERs expression in sensory neurons may represent a novel mechanism that can explain the sex differences in nociception observed in clinical practice.

  9. An interaction between P2X3 and membrane-associated ERalpha (show ESR1 Proteins) in primary sensory neurones that may represent a novel mechanism to explain sex differences observed in the clinical presentation of visceral nociceptive syndromes.

  10. Transcripts for P2X3 were present in nearly all colon neurons examined. About half of the cells only containing P2X3 transcripts, and zymosan did not change this. The fast current triggered by ATP and alpha,beta-meATP is dependent on P2X3 receptors.

Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Protein Profile

Protein Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Gene names and symbols associated with P2RX3

  • purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3)
  • purinergic receptor P2X, ligand-gated ion channel, 3 (P2rx3)
  • 4930513E20Rik protein
  • P2RX3 protein
  • P2X3 protein

Protein level used designations for P2RX3

purinergic receptor P2X, ligand-gated ion channel, 3 , P2X3 purinoceptor , purinergic receptor P2X3 , ATP receptor , P2X purinoceptor 3 , P2X3 , P2X receptor, subunit 3 , purinoceptor P2X3

GENE ID SPECIES
428856 Gallus gallus
448782 Canis lupus familiaris
530468 Bos taurus
742961 Pan troglodytes
81739 Rattus norvegicus
5024 Homo sapiens
228139 Mus musculus
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