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Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. Additionally we are shipping PDXP Kits (17) and PDXP Proteins (11) and many more products for this protein.
Showing 10 out of 18 products:
Cow (Bovine) Polyclonal PDXP Primary Antibody for WB - ABIN2787198
Gohla, Birkenfeld, Bokoch: Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. in Nature cell biology 2005
Chronophin has a role in coordinating cell leading edge dynamics by controlling active cofilin (show CFL1 Antibodies) levels
Splicing of SH3BP1 (show SH3BP1 Antibodies) and CIN gene loci produces the novel brain specific (show CALY Antibodies) splice variant BGIN.
analysis of pyridoxal phosphatase cloning, expression and tissue distribution
We report the biochemical isolation of chronophin (CIN), a unique cofilin (show CFL1 Antibodies)-activating phosphatase of the haloacid dehalogenase (HAD) superfamily and an important novel regulator of cofilin (show CFL1 Antibodies)-mediated actin reorganization.
Results suggest that the transduction of the PEP-1-PLPP fusion protein can be one mode of PLP (show PLP1 Antibodies) level regulation, and to replenish this enzyme in the various neurological disorders related to vitamin B(6).
Study demonstrates the ATP-sensitive interaction of the cofilin (show CFL1 Antibodies) phosphatase chronophin (CIN) with the chaperone hsp90 (show HSP90 Antibodies) to form a biosensor that mediates cofilin (show CFL1 Antibodies)/actin rod formation.
Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities.
Dimer formation is essential for an intermolecular arginine-arginine-tryptophan stacking interaction that positions a critical histidine residue in the substrate specificity loop of chronophin for PLP (show C3 Antibodies) coordination.
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003
, pyridoxal phosphate phosphatase
, pyridoxal phosphatase
, reg I binding protein I
, reg I-binding protein 1