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The protein encoded by PPA1 is a member of the inorganic pyrophosphatase (PPase) family. Additionally we are shipping Pyrophosphatase (Inorganic) 1 Antibodies (43) and Pyrophosphatase (Inorganic) 1 Kits (4) and many more products for this protein.
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Human PPA1 Protein expressed in Escherichia coli (E. coli) - ABIN667664
Carman, Han: Roles of phosphatidate phosphatase enzymes in lipid metabolism. in Trends in biochemical sciences 2006
Show all 2 references for ABIN667664
PP-1 and Akt (show AKT1 Proteins) have roles in AR-v7 protein expression and activities when AR is functionally blocked
The Newcastle disease virus-induced translation shutoff at late infection times was attributed to sustaining phosphorylation of eIF2a (show EIF2S1 Proteins), which is mediated by continual activation of PKR (show PKLR Proteins) and degradation of PP1.
The human PP1 interaction with the measles V protein is mediated by a conserved PP1-binding motif in the C-terminal region of the V protein.
Measles virus binding to DC-SIGN (show CD209 Proteins) leads to inhibition of PP1 phosphatase activity and hence inhibition of RIG-I (show DDX58 Proteins) and Mda5 (show IFIH1 Proteins) dephosphorylation.
Results identify PP1 as a novel regulator of Cl(-)-HCO3(-) anion exchangers activity which, in concert with CFTR (show CFTR Proteins), coordinates events at both apical and basolateral membranes, crucial for efficient HCO3(-) secretion from Calu (show CALU Proteins)-3 cells.
findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 (show MARK3 Proteins) and PFTK1 (show CDK14 Proteins)
PPP1R42 (show PPP1R42 Proteins) regulation of PP1 function in centrosome separation.
PP1gamma is the major histone H3 (show HIST3H3 Proteins) phosphatase acting on the mitotically phosphorylated residues H3T3ph, H3S10ph, H3T11ph, and H3S28ph.
IRBIT (show AHCYL1 Proteins) opposes the effects of WNKs and SPAK (show STK39 Proteins) by recruiting PP1 to the complex to dephosphorylate CFTR (show CFTR Proteins) and NBCe1 (show SLC4A4 Proteins)-B, restoring their cell surface expression, in addition to stimulating their activities
Data are consistent with the postsynaptic gephyrin (show GPHN Proteins) scaffold acting as a platform for protein phosphatase 1 (show PPP1CB Proteins) (PP1), which regulates gephyrin (show GPHN Proteins) cluster size by dephosphorylation of gephyrin (show GPHN Proteins)- or cytoskeleton-associated proteins.
PPA1 may play a role in neuronal differentiation via JNK (show MAPK8 Proteins) dephosphorylation.
IRBIT (show AHCYL1 Proteins) opposes the effects of WNKs and SPAK (show STK39 Proteins) by recruiting PP1 (show PPP1CC Proteins) to the complex to dephosphorylate CFTR (show CFTR Proteins) and NBCe1 (show SLC4A4 Proteins)-B, restoring their cell surface expression, in addition to stimulating their activities
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme.
, Inorganic pyrophosphatase
, cytosolic inorganic pyrophosphatase
, diphosphate phosphohydrolase
, inorganic diphosphatase
, inorganic pyrophosphatase 1
, pyrophosphatase 1
, pyrophosphate phospho-hydrolase