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RAB25, Member RAS Oncogene Family Proteins (RAB25)

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Additionally we are shipping RAB25 Antibodies (64) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAB25 57111 P57735
RAB25 53868 Q9WTL2
Rat RAB25 RAB25 310632  
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Top RAB25 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,517.17
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,517.17
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,517.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RAB25 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for RAB25, Member RAS Oncogene Family (RAB25) Interaction Partners

Human RAB25, Member RAS Oncogene Family (RAB25) interaction partners

  1. Rab25 expression is a potential prognostic index for advanced NSCLC patients and its inhibition may improve chemosensitization in NSCLC treatment.

  2. These results showed that high levels of Rab25 expression were significantly correlated with renal cell carcinoma (show MOK Proteins) invasion classification (P < 0.01), lymph-node metastasis (P < 0.001), and pathological stage (P < 0.01).

  3. High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.

  4. the crystal structure of Rab25 in complex with the C-terminal region of FIP2 (show OPTN Proteins), which consists of a central dimeric FIP2 (show OPTN Proteins) coiled-coil that mediates a heterotetrameric Rab25-(FIP2 (show OPTN Proteins))2-Rab25 complex.

  5. Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt (show AKT1 Proteins)/GSK-3beta/Snail (show SNAI1 Proteins) signaling.

  6. These findings suggest that Rab25 plays an important role in tumor migration and metastasis, and that understanding its function may lead to the development of new strategies to prevent metastasis in oral cancer patients.

  7. Rab25 controls intestinal cell polarity through the regulation of gene expression

  8. RAB25 has been implicated in various cancers, with reports presenting it as both an oncogene (show RAB1A Proteins) and a tumour-suppressor gene. [Review]

  9. Studies using lentiviral-based overexpression and suppression systems lent support of Rab25 to function as an important tumor suppressor with both anti-invasive and -angiogenic abilities, through a deregulated FAK (show PTK2 Proteins)-Raf (show RAF1 Proteins)-MEK1 (show MAP2K1 Proteins)/2-ERK (show EPHB2 Proteins) signaling pathway.

  10. data showed Rab25 was highly expressed in all subtypes of epithelial ovarian cancers, and two subtypes of germ cell tumors, but not in sex cord stromal tumors; Rab25 expression was not correlated with peritoneal metastasis of ovarian cancer

Mouse (Murine) RAB25, Member RAS Oncogene Family (RAB25) interaction partners

  1. a Grhl2 (show GRHL2 Proteins)/Ovol2 (show OVOL2 Proteins) network controls Cldn4 (show CLDN4 Proteins) and Rab25 expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia

  2. tight regulation of CCN3 (show NOV Proteins) expression is necessary for normal cortical neuronal connectivity during development, and RAB25 negatively regulates neuronal differentiation as a downstream effector of CCN3 (show NOV Proteins)

  3. the results indicate that Grhl2 (show GRHL2 Proteins) regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 (show CLDN3 Proteins) and Cldn4 (show CLDN4 Proteins), as well as of Rab25, which increases the Cldn4 (show CLDN4 Proteins) protein and its localization at TJs

  4. Rab25 may function as a tumor suppressor in intestinal epithelial cells through regulation of protein trafficking to the cell surface.

RAB25 Protein Profile

Protein Summary

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007

Gene names and symbols associated with RAB25

  • RAB25, member RAS oncogene family (rab25)
  • RAB25, member RAS oncogene family (RAB25)
  • RAB25, member RAS oncogene family a (rab25a)
  • RAB25 (LOC100152692)
  • RAB25, member RAS oncogene family (Rab25)
  • AV012978 protein
  • CATX-8 protein
  • MGC79587 protein
  • MGC84182 protein
  • RAB11C protein
  • rab25 protein
  • si:dkeyp-84f11.7 protein
  • zgc:101648 protein

Protein level used designations for RAB25

RAB25, member RAS oncogene family , ras-related protein Rab-25 , Ras-related protein Rab-25 , small GTP-binding protein

GENE ID SPECIES
444652 Xenopus laevis
457382 Pan troglodytes
493286 Xenopus (Silurana) tropicalis
494098 Danio rerio
718131 Macaca mulatta
100286660 Salmo salar
100152692 Sus scrofa
57111 Homo sapiens
506482 Bos taurus
53868 Mus musculus
310632 Rattus norvegicus
490418 Canis lupus familiaris
100009059 Oryctolagus cuniculus
100858582 Gallus gallus
101084416 Felis catus
101123339 Ovis aries
100720999 Cavia porcellus
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