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anti-RAB27A, Member RAS Oncogene Family (RAB27A) Antibodies

The protein encoded by RAB27A belongs to the small GTPase superfamily, Rab family. Additionally we are shipping RAB27A Proteins (17) and RAB27A Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAB27A 5873 P51159
RAB27A 11891 Q9ERI2
RAB27A 50645 P23640
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Top anti-RAB27A Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RAB27A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB RAB27A monoclonal antibody (M01), clone 4C1. Western Blot analysis of RAB27A expression in HL-60. Detection limit for recombinant GST tagged RAB27A is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB RAB27A Antibody (C-term) (ABIN1881720) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the RAB27A antibody detected the RAB27A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western blot analysis of Rab27 in human chronic myelogenous leukemia. Lysate from the K-562 cell line (ABIN968586) was probed with purified mouse anti-Rab27 monoclonal antibody at concentrations of 1.00, 0.50, and 0.25 µg/ml (Lanes 1, 2, and 3, respectively). Rab27 is identified as a band of 25 kDa. 0.1 mg Log in to see 5 to 6 Days
$423.33
Details
Human Mouse Un-conjugated IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to RAB27A on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml] RAB27A monoclonal antibody (M02), clone 1G7 Western Blot analysis of RAB27A expression in HL-60 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Rab27a  Sample Tissue: Mouse Pancreas  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Rat Rabbit Un-conjugated IP, WB dilution: 1 : 1000, sample: crude synaptic vesicle fraction of rat brain (LP2) 50 μg Log in to see 5 to 6 Days
$398.48
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB RAB27A antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

RAB27A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Top referenced anti-RAB27A Antibodies

  1. Human Monoclonal RAB27A Primary Antibody for IHC (p), RNAi - ABIN562560 : Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines. in Journal of cell science 2008 (PubMed)
    Show all 7 references for ABIN562560

  2. Human Monoclonal RAB27A Primary Antibody for WB - ABIN396260 : Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. in Pigment cell & melanoma research 2010 (PubMed)
    Show all 5 references for ABIN396260

  3. Human Polyclonal RAB27A Primary Antibody for WB - ABIN1881720 : Meeths, Bryceson, Rudd, Zheng, Wood, Ramme, Beutel, Hasle, Heilmann, Hultenby, Ljunggren, Fadeel, Nordenskjöld, Henter: Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. in Pediatric blood & cancer 2010 (PubMed)
    Show all 5 references for ABIN1881720

  4. Human Monoclonal RAB27A Primary Antibody for WB - ABIN967619 : Hong: Cytotoxic T lymphocyte exocytosis: bring on the SNAREs! in Trends in cell biology 2005 (PubMed)
    Show all 3 references for ABIN967619

  5. Rat (Rattus) Polyclonal RAB27A Primary Antibody for IP, WB - ABIN1742354 : Lovis, Roggli, Laybutt, Gattesco, Yang, Widmann, Abderrahmani, Regazzi: Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. in Diabetes 2008 (PubMed)

  6. Human Polyclonal RAB27A Primary Antibody for WB - ABIN2786786 : Chiaverini, Beuret, Flori, Busca, Abbe, Bille, Bahadoran, Ortonne, Bertolotto, Ballotti: Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against RAB27A Interaction Partners

Human RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. decreased expression of Rab27A and Rab27B (show RAB27B Antibodies), especially Rab27A, closely correlated with tumor progression and are valuable prognostic indicators in colorectal cancer patients.

  2. We report two unrelated teenagers with hemophagocytic lymphohistiocytosis and an identical heterozygous RAB27A mutation (c.259G-->C).

  3. Data suggest that microRNA miR (show MLXIP Antibodies)-582-5p may function as a tumor suppressor in the development of colorectal carcinoma (CRC (show CALR Antibodies)) by targeting RAS-related GTP-binding protein (show RAB10 Antibodies) (Rab27a), indicating a novel therapeutic strategy for patients with CRC (show CALR Antibodies).

  4. Experimental data are reviewed with a focus on the secretory Rab27 family of small GTPases and their implications in cancer progression.

  5. miR (show MLXIP Antibodies)-122 has a Rab27a-dependent function in the hepatitis C virus lifecycle

  6. Rab27A may be used as a valuable prognostic biomarker for colorectal carcinoma patients.

  7. Our data indicate that RAB27A expression is an independent prognostic marker for pancreatic ductal adenocarcinoma

  8. This study identified a common variant located in RAB27A gene influencing FeNO levels specifically in adults and with a biological relevance to the regulation of FeNO levels.

  9. These studies highlight the need for RAB27A sequencing in patients with FHL (show FHL1 Antibodies) with normal pigmentation and identify a critical binding site for Munc13-4 (show UNC13D Antibodies) on Rab27a, revealing the molecular basis of this interaction.

  10. Data show that cystic fibrosis (show S100A8 Antibodies) (CF) neutrophils release less secondary and tertiary granule components and that activation of the low-molecular-mass GTP-binding protein Rab27a, involved in the regulation of granule trafficking, is defective.

Mouse (Murine) RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. Given that GTP (show AK3 Antibodies)- and GDP-bound Rab27a regulate exocytosis.

  2. This paper showed an inhibitory effect of Rab27a directly at the pore forming CaV1.3 (show CACNA1D Antibodies) subunit of L-type channels, leading to decreased current density and reduced VEGF-A (show VEGFA Antibodies) secretion by the retinal pigment epithelium.

  3. results show that Rab27A is present in mouse pancreatic acinar cells and mainly regulates secretion through the minor-regulated pathway

  4. Rab27A deficiency shows the increased surface level of c-fms (show CSF1R Antibodies), and the delayed downregulation of RANK in ashen cells, resulting in enhanced signaling of M-CSF (show CSF1R Antibodies) and RANKL (show TNFSF11 Antibodies).

  5. Rab27b (show RAB27B Antibodies) is expressed in bone marrow derived neutrophils and Rab27b (show RAB27B Antibodies) knockout (Rab27b (show RAB27B Antibodies) KO) along with Rab27a/b double knockout (Rab27DKO) neutrophils exhibit impaired transwell migration in vitro in response to chemokines MIP-2 (show CXCL2 Antibodies) and LTB4 (show PTGR1 Antibodies).

  6. Our findings indicate that Slp2-a (show SYTL2 Antibodies) controls renal cell size through regulation of Rap (show LRPAP1 Antibodies)-ezrin (show EZR Antibodies) signaling independently of Rab27.

  7. The results showed that Rab27A(Q78L) is unable to localize on mature melanosomes and that its inhibitory activity on melanosome transport is completely dependent on its binding to the Rab27A effector Slac2-a/melanophilin (show MLPH Antibodies).

  8. Rab27a has a key role in eosinophil degranulation. Furthermore, these findings have implications for Rab27a-dependent eosinophil degranulation in airway inflammation.

  9. Upregulation of the Rab27a-dependent lysosomal trafficking and secretory pathways contributes to the correction of some of the cellular defects induced by lysosomal overload in cystinosis, including endoplasmic reticulum stress.

  10. Data suggest that Rab27a and Rab27b (show RAB27B Antibodies) regulate distinct steps in the bone marrow-derived mast cells (BMMC) degranulation pathway, with Rab27a/Mlph (show MLPH Antibodies)/MyoVa (show MYO5A Antibodies) regulating cortical actin stability upstream of Rab27a/b/Munc13-4 (show UNC13D Antibodies)-dependent granule exocytosis.

RAB27A Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Gene names and symbols associated with RAB27A

  • RAB27A, member RAS oncogene family (rab27a) antibody
  • RAB27A, member RAS oncogene family (RAB27A) antibody
  • RAB27A, member RAS oncogene family (rab27a-b) antibody
  • RAB27A, member RAS oncogene family (Rab27a) antibody
  • 2210402C08Rik antibody
  • 2410003M20Rik antibody
  • 4933437C11Rik antibody
  • ash antibody
  • GS2 antibody
  • HsT18676 antibody
  • MGC80943 antibody
  • MGC89827 antibody
  • RAB27 antibody
  • RAB27A antibody
  • RAM antibody
  • zgc:114135 antibody

Protein level used designations for RAB27A

RAB27A, member RAS oncogene family , Ras-related protein Rab-27A , rab27a, member ras oncogene family , ras-related protein Rab-27A , GTP-binding protein Ram , rab-27 , member RAS oncogene family, RAB27A , ashen , low Mr GTP-binding protein , ram p25 , RAS oncogene family member

GENE ID SPECIES
444290 Xenopus laevis
453455 Pan troglodytes
493339 Xenopus (Silurana) tropicalis
494641 Xenopus laevis
570907 Danio rerio
5873 Homo sapiens
606749 Sus scrofa
618035 Bos taurus
11891 Mus musculus
50645 Rattus norvegicus
608699 Canis lupus familiaris
415410 Gallus gallus
101086976 Felis catus
101122791 Ovis aries
100720981 Cavia porcellus
Selected quality suppliers for anti-RAB27A (RAB27A) Antibodies
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