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RAB34 encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. Additionally we are shipping RAB34 Proteins (9) and many more products for this protein.
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Although Rab34 regulates both lysosomal positioning and lysosome to phagosome fusion, the latter effect is not due to the regulation of the cytoplasmic accessibility of lysosomes to phagosomes by Rab34.
uncover Rab34/Munc13-2 (show UNC13B Antibodies) as a critical part of an alternative Rab7 (show RAB7A Antibodies)-independent phagosome maturation machinery and lysosome-mediated killing of mycobacteria
results have uncovered a novel mechanism for interorganellar trans-regulation of spatial distribution of lysosomes by Golgi-associated Rab34
NARR is ubiquitously expressed and resides in nucleoli where it colocalizes with ribosomal DNA gene clusters.
MMP19 (show MMP19 Antibodies) were positively correlated with RAB34.
Rab36 (show RAB36 Antibodies) may regulate the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34.
The data together indicate that RILP (show RILP Antibodies), as already demonstrated for several other Rab (show HRB Antibodies) effector proteins, is capable of self-association, thus probably forming a homo-dimer.
Data suggest that diacylglycerol-activated hmunc13 serves as an effector of Rab34, mediating lysosome-Golgi trafficking.
define Rab34 as a novel member of the secretory pathway acting at the Golgi
B coxsackievirus entry depends on occludin (show OCLN Antibodies) and require the activity of Rab34, Ras, and Rab5 (show RAB5A Antibodies), GTPases known to regulate macropinocytosis.
mechanistic basis for high glucose-induced protein secretion is through interaction of munc13 (show UNC13B Antibodies) and rab34, indicating a potentially critical role for this newly described pathway in the pathogenesis of DN.
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame.
, ras-related homolog
, ras-related protein Rab-34
, ras-related protein Rab-39
, ras-related protein Rah
, RAB34, member of RAS oncogene family
, Ras-related protein RAB34