RAB35, Member RAS Oncogene Family Proteins (RAB35)

In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. Additionally we are shipping RAB35 Antibodies (65) and RAB35 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAB35 11021 Q15286
RAB35 77407 Q6PHN9
RAB35 288700 Q5U316
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Top RAB35 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,489.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$498.21
Details

RAB35 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced RAB35 Proteins

  1. Human RAB35 Protein expressed in Escherichia coli (E. coli) - ABIN667954 : Kouranti, Sachse, Arouche, Goud, Echard: Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis. in Current biology : CB 2006 (PubMed)
    Show all 2 references for 667954

More Proteins for RAB35, Member RAS Oncogene Family (RAB35) Interaction Partners

Human RAB35, Member RAS Oncogene Family (RAB35) interaction partners

  1. The involvement of Rab35 in diverse and apparently unrelated cellular functions can be explained by the central role of this GTPase in regulating phosphoinositides and F-actin, both on endosomes and at the plasma membrane[review].

  2. Data suggest that Rab35, interacting with TBC1D10A (show TBC1D10A Proteins), functions in vascular endothelial cells as a negative regulator of histamine-evoked, Ca2 (show CA2 Proteins)+-dependent Weibel-Palade body exocytosis, most likely acting through the downstream effectors ACAP2 (show ACAP2 Proteins) and Arf6 (show ARF6 Proteins). (Rab35 = rab (show HRB Proteins) GTP-binding protein 53 (show IGFBP3 Proteins); TBC1D10A (show TBC1D10A Proteins) = TBC1 domain family member 10A (show TBC1D10A Proteins); ACAP2 (show ACAP2 Proteins) = centaurin beta2; Arf6 (show ARF6 Proteins) = ADP-ribosylation factor 6 (show ARF6 Proteins))

  3. Short-term EGF (show EGF Proteins) stimulation if of lung tumor cells can increase the interaction between RUSC2 and GIT2 (show GIT2 Proteins), prolonged stimulation leads to a decrease of their interaction through activating Rab35.

  4. Here the authors report that EspG interacts specifically with the small GTPases ARF6 (show ARF6 Proteins) and Rab35 during infection.

  5. Authors propose that the precise spatial and temporal activation of Rab35 acts as a major switch for OCRL (show OCRL Proteins) recruitment on newborn endosomes, post-scission PtdIns(4,5)P2 hydrolysis, and subsequent endosomal trafficking.

  6. Rab35 serves as a clathrin-mediated endocytosis detector. Loss of Rab35 input leads to elevated Arf6-GTP and shifts the sorting of clathrin-independent endocytosis cargo proteins to lysosomes.

  7. the activation-inactivation cycles of Rab35 and ARF6 (show ARF6 Proteins) are required for the uptake of zymosan and that ACAP2 (show ACAP2 Proteins) is an important component that links Rab35/ARF6 (show ARF6 Proteins) signaling during phagocytosis of zymosan.

  8. Two somatic RAB35 mutations found in human tumors generate alleles that constitutively activate PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling, suppress apoptosis, and transform cells in a PI3K (show PIK3CA Proteins)-dependent manner.

  9. mutual regulation with arf6 (show ARF6 Proteins) of cell adhesion and migration

  10. Rab35 acts as a downstream target of Dvl2 (show DVL2 Proteins) and mediates cell migration.

Mouse (Murine) RAB35, Member RAS Oncogene Family (RAB35) interaction partners

  1. This study demonstrated that Rab35 regulates Cdc42 (show CDC42 Proteins) activity in neurons.

  2. The Rab35 plays an important role in spindle organization and morphology maintenance, and thus meiotic nuclear maturation.

  3. Rab35 regulates myoblast fusion, a major cellular process under the control of cadherin-dependent signaling.

  4. Rab35 regulates phagosome formation through recruitment of ACAP2 (show ACAP2 Proteins) in macrophages during FcgammaR-mediated phagocytosis.

  5. The minimal functional Rab35-binding site of RUSC2 was identified at the amino acid residues 982-1199 and succeeded in developing a novel GTP (show AK3 Proteins)-Rab35-specific trapper.

  6. Rab35 colocalizes with actin filaments and with Cdc42 (show CDC42 Proteins), Rac1 and RhoA (show RHOA Proteins), and that Rab35 can activate Cdc42 (show CDC42 Proteins) both in vivo and in vitro

  7. study found that Rab35 regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin (show FSCN1 Proteins), which directly associated with active Rab35

RAB35 Protein Profile

Protein Summary

In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge.

Gene names and symbols associated with RAB35

  • RAB35, member RAS oncogene family (rab35)
  • RAB35, member RAS oncogene family (RAB35)
  • RAB35, member RAS oncogene family (LOC100230414)
  • RAB35, member RAS oncogene family (Rab35)
  • 9530019H02Rik protein
  • AU040256 protein
  • dZ146N9.2 protein
  • H-ray protein
  • MGC69101 protein
  • MGC76044 protein
  • RAB1C protein
  • RAY protein
  • si:busm1-146n9.2 protein
  • zgc:100812 protein

Protein level used designations for RAB35

RAB35, member RAS oncogene family , ras-related protein Rab-35 , GTP-binding protein RAY , ras-related protein rab-1c (GTP-binding protein ray)

GENE ID SPECIES
379665 Xenopus laevis
394615 Xenopus (Silurana) tropicalis
445154 Danio rerio
698400 Macaca mulatta
100196061 Salmo salar
100230414 Taeniopygia guttata
100528153 Ictalurus punctatus
11021 Homo sapiens
77407 Mus musculus
288700 Rattus norvegicus
416983 Gallus gallus
611477 Canis lupus familiaris
614521 Bos taurus
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