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Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010].. Additionally we are shipping Rab5c Proteins (12) and many more products for this protein.
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Human Polyclonal Rab5c Primary Antibody for ICC, IF - ABIN4348962
Chen, Kong, Su, Stahl: Rab5 isoforms differentially regulate the trafficking and degradation of epidermal growth factor receptors. in The Journal of biological chemistry 2009
Show all 3 Pubmed References
Treatment of macrophages with IL-6 (show IL6 Antibodies) specifically induce the expression of Rab5 (show RAB5A Antibodies) through the activation of extracellular signal-regulated kinase, whereas IL-12 (show IL12A Antibodies) exclusively upregulate the expression of Rab7 (show RAB7A Antibodies) through the activation of p38 MAPK (show MAPK14 Antibodies).
Enforced miR (show MLXIP Antibodies)-509 expression in NALM6 cells reduced RAB5C mRNA and protein levels, and RAB5C was demonstrated to be a direct target of miR (show MLXIP Antibodies)-509.
PLP2 and RAB5C are binding partners of TPD52.
Rab5C modulates Rac1-mediated cell motility.
GTP (show AK3 Antibodies)-Rab5c also bound to AMAP1 (show ASAP1 Antibodies), and activation of Rab5c by EGFR (show EGFR Antibodies) signaling was necessary to promote the intracellular association of AMAP1 (show ASAP1 Antibodies) and PRKD2 (show PKD2 Antibodies)
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996
RAB5C, member RAS oncogene family
, ras-related protein Rab-5C
, RAB5C, member of RAS oncogene family
, RAB5B, member RAS oncogene family
, rab5C-like protein