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RASAL2 encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). Additionally we are shipping and many more products for this protein.
Showing 10 out of 33 products:
Human Polyclonal RASAL2 Primary Antibody for EIA, WB - ABIN954459
Shibui, Kobayashi, Shiratori: Isolation of cross-reacting antigen candidates by mRNA-display using a mixed cDNA library. in Biotechnology letters 2008
Show all 4 references for ABIN954459
Human Polyclonal RASAL2 Primary Antibody for ICC, IF - ABIN4349403
Feng, Bao, Li, Li, Gong, Lam, Wang, Marzese, Donovan, Tan, Hoon, Yu: RASAL2 activates RAC1 to promote triple-negative breast cancer progression. in The Journal of clinical investigation 2014
these results demonstrated that miRNA-136 was a key anti-invasive miRNA and further confirmed the oncogenic role of RASAL2 in triple-negative breast cancer.
High RASAL2 expression is associated with liver cancer.
these results indicate that activation of a RASAL2/ARHGAP24 (show ARHGAP24 Antibodies)/RAC1 module contributes to TNBC tumorigenesis and identify a context-dependent role of RASAL2 in breast cancer.
Results implicate RASAL2 as an EMT (show ITK Antibodies) regulator and tumor suppressor in ovarian cancer, and down-regulation of RASAL2 promotes ovarian cancer progression.
the down-regulation of RASAL2 promotes metastatic progression of lung adenocarcinoma
The RasGAP (show RASA1 Antibodies) gene, RASAL2, is a tumor and metastasis suppressor.
RASAL2 was identified as an ECT2 (show ECT2 Antibodies)-interacting protein that regulates RHO activity in astrocytoma cells.
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
RAS protein activator-like 2
, Ras protein activator like 1
, ras GTPase-activating protein nGAP