anti-REC8 Homolog (Yeast) (REC8) Antibodies

REC8 encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. Additionally we are shipping REC8 Proteins (5) and REC8 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
REC8 56739 Q8C5S7
REC8 9985 O95072
REC8 290227 Q6AYJ4
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Top anti-REC8 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-REC8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>721_B cell lysate Host: Rabbit <br /> Target Name: REC8 <br /> Sample Tissue: Human Fetal Heart <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB REC8 Antibody (Center) (ABIN657493) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the REC8 antibody detected the REC8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87144] - Staining of human testis shows strong nuclear positivity in secondary spermatocytes. Western Blot: REC8 Antibody [NBP1-87144] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti phospho-REC8(Ser251) Polyclonal Antibody, Unconjugated (ABIN872285) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti phospho-REC8(Ser251) Polyclonal Antibody, Unconjugated  followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat testis labeled with Anti REC8 Polyclonal Antibody, Unconjugated (ABIN873082) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Mouse Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$427.90
Details
Mouse Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$427.90
Details

REC8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-REC8 Antibodies

  1. Human Polyclonal REC8 Primary Antibody for IHC, IHC (p) - ABIN4349769 : Lindsey, Byrnes, Eller, Rosa, Dabas, Escandon, Grichnik: Potential role of meiosis proteins in melanoma chromosomal instability. in Journal of skin cancer 2013 (PubMed)

More Antibodies against REC8 Interaction Partners

Cow (Bovine) REC8 Homolog (Yeast) (REC8) interaction partners

  1. We fine-map three QTL and present strong evidence that genetic variants in REC8 and RNF212 (show RNF212 Antibodies) influence genome-wide recombination rate, while genetic variants in PRDM9 (show PRDM9 Antibodies) influence genome-wide hotspot usage.

Mouse (Murine) REC8 Homolog (Yeast) (REC8) interaction partners

  1. Our genetic analysis demonstrates that cohesins containing STAG3 and REC8 are the main complex required for centromeric cohesion, and RAD21L cohesins are required for normal clustering of pericentromeric heterochromatin. Furthermore, the STAG3/REC8 and STAG3/RAD21L cohesins are the primary cohesins required for axis formation.

  2. REC8-containing cohesin complexes provide canonical SCC, not RAD21 or RAD21L, at the prophase stage of meiosis I in spermatocytes.

  3. To decipher the functions of the two meiosis-specific kleisins, REC8 or RAD21L, together with the only meiosis-specific SMC protein SMC1b, we generated Smc1b-/-Rec8-/- and Smc1b-/-Rad21L-/- mouse mutants.

  4. Rec8 establishes cohesion when activated during DNA replication in fetal oocytes using tamoxifen-inducible Cre. In contrast, no new cohesion is detected when Rec8 is activated in arrested oocytes by tamoxifen despite cohesin synthesis.

  5. Plk1 (show PLK1 Antibodies) activity is required for meiotic spindle assembly and REC8 cleavage, with pPlk1Ser137 being the action executor, in mouse oocytes during meiotic division.

  6. effects ofAte1ablation are inferred to be caused, at least in part, by the failure to destroy the C-terminal fragment of Rec8 in the absence of N-terminal arginylation.

  7. Our findings strengthen the importance of RA and Dazl (show DAZL Antibodies) in the meiotic transition, provide important details about the Stra8 (show STRA8 Antibodies) pathway, and open avenues to investigate early meiosis through analysis of Rec8 induction and function

  8. STAG3-REC8 cohesin complexes have a critical role in supporting meiotic chromosome structure and functions.

  9. Findings indicate that cohesin-mediated long-range interactions facilitate discrete gene expression states within preexisting chromosomal compartments.

  10. Data show that nociceptin (show PNOC Antibodies) induces Rec8 phosphorylation, triggering chromosome dynamics, in spermatocytes during meiosis in postnatal testes.

Human REC8 Homolog (Yeast) (REC8) interaction partners

  1. Study confirmed that REC8 was downregulated in gastric neoplasm, especially in the EBV-associated subtype, via promoter methylation.

  2. REC8 being a novel major bona fide tumor suppressor gene and a robust epigenetic target of the PI3K (show PIK3CA Antibodies) pathway. Aberrant inactivation of REC8 through hypermethylation by the PI3K (show PIK3CA Antibodies) pathway may represent an important mechanism mediating the oncogenic functions of the PI3K (show PIK3CA Antibodies) pathway

  3. Indicate that polymorphisms of the Rec 8 gene are not a common cause of severe male factor infertility.

  4. Data show that REC8 is constitutively expressed in tumour cells, along with SGOL1 (show SGOL1 Antibodies) and SGOL2 (show SGOL2 Antibodies), and that REC8 becomes modified after irradiation.

  5. The mouse ortholog of REC8L1 is required for proper synapsis of homologous chromosomes during meiosis

REC8 Antigen Profile

Protein Summary

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene names and symbols associated with REC8

  • REC8 homolog (yeast) (REC8) antibody
  • REC8 homolog (yeast) (Rec8) antibody
  • REC8 meiotic recombination protein (REC8) antibody
  • REC8 meiotic recombination protein (Rec8) antibody
  • HR21spB antibody
  • mrec antibody
  • REC8L1 antibody
  • Rec8p antibody

Protein level used designations for REC8

REC8 homolog (yeast) , meiotic recombination protein REC8 homolog , REC8-like 1 , cohesin Rec8p , meiotic cohesion Rec8 , REC8 homolog , cohesion rec8p , human homolog of rad21, S. pombe , kleisin-alpha , meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family , meiotic recombination protein REC8-like 1 , recombination and sister chromatid cohesion protein homolog , meiosis specific sister chromatid cohesion protein

GENE ID SPECIES
100581128 Nomascus leucogenys
490622 Canis lupus familiaris
516291 Bos taurus
56739 Mus musculus
100127457 Sus scrofa
100713854 Cavia porcellus
9985 Homo sapiens
290227 Rattus norvegicus
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