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REC8 Homolog (Yeast) (REC8) ELISA Kits

REC8 encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. Additionally we are shipping REC8 Antibodies (75) and REC8 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
REC8 56739 Q8C5S7
REC8 9985 O95072
REC8 290227 Q6AYJ4
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.78-50 ng/mL 96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days
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More ELISA Kits for REC8 Interaction Partners

Cow (Bovine) REC8 Homolog (Yeast) (REC8) interaction partners

  1. We fine-map three QTL and present strong evidence that genetic variants in REC8 and RNF212 influence genome-wide recombination rate, while genetic variants in PRDM9 (show PRDM9 ELISA Kits) influence genome-wide hotspot usage.

Mouse (Murine) REC8 Homolog (Yeast) (REC8) interaction partners

  1. To decipher the functions of the two meiosis-specific kleisins, REC8 or RAD21L, together with the only meiosis-specific SMC protein SMC1b, we generated Smc1b-/-Rec8-/- and Smc1b-/-Rad21L-/- mouse mutants.

  2. Rec8 establishes cohesion when activated during DNA replication in fetal oocytes using tamoxifen-inducible Cre. In contrast, no new cohesion is detected when Rec8 is activated in arrested oocytes by tamoxifen despite cohesin synthesis.

  3. Plk1 (show PLK1 ELISA Kits) activity is required for meiotic spindle assembly and REC8 cleavage, with pPlk1Ser137 being the action executor, in mouse oocytes during meiotic division.

  4. effects ofAte1ablation are inferred to be caused, at least in part, by the failure to destroy the C-terminal fragment of Rec8 in the absence of N-terminal arginylation.

  5. Our findings strengthen the importance of RA and Dazl (show DAZL ELISA Kits) in the meiotic transition, provide important details about the Stra8 pathway, and open avenues to investigate early meiosis through analysis of Rec8 induction and function

  6. STAG3-REC8 cohesin complexes have a critical role in supporting meiotic chromosome structure and functions.

  7. Findings indicate that cohesin-mediated long-range interactions facilitate discrete gene expression states within preexisting chromosomal compartments.

  8. Data show that nociceptin (show PNOC ELISA Kits) induces Rec8 phosphorylation, triggering chromosome dynamics, in spermatocytes during meiosis in postnatal testes.

  9. We report here evidence from the mouse that partial loss of gene function for either Smc1b (show SMC1B ELISA Kits) or Rec8 causes perturbations in the formation of the synaptonemal complex (SC) and affects both synapsis and recombination between homologs during meiotic prophase

  10. show that spermatocytes from mice lacking the two meiosis-specific cohesin subunits RAD21L and REC8 were unable to initiate RAD51 (show RAD51 ELISA Kits)- but not DMC1 (show DMC1 ELISA Kits)-mediated double-strand break repair

Human REC8 Homolog (Yeast) (REC8) interaction partners

  1. REC8 being a novel major bona fide tumor suppressor gene and a robust epigenetic target of the PI3K (show PIK3CA ELISA Kits) pathway. Aberrant inactivation of REC8 through hypermethylation by the PI3K (show PIK3CA ELISA Kits) pathway may represent an important mechanism mediating the oncogenic functions of the PI3K (show PIK3CA ELISA Kits) pathway

  2. Indicate that polymorphisms of the Rec 8 gene are not a common cause of severe male factor infertility.

  3. Data show that REC8 is constitutively expressed in tumour cells, along with SGOL1 (show SGOL1 ELISA Kits) and SGOL2, and that REC8 becomes modified after irradiation.

  4. The mouse ortholog of REC8L1 is required for proper synapsis of homologous chromosomes during meiosis

REC8 Antigen Profile

Antigen Summary

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene names and symbols associated with REC8 Homolog (Yeast) (REC8) ELISA Kits

  • REC8 homolog (yeast) (REC8) antibody
  • REC8 homolog (yeast) (Rec8) antibody
  • REC8 meiotic recombination protein (REC8) antibody
  • REC8 meiotic recombination protein (Rec8) antibody
  • HR21spB antibody
  • mrec antibody
  • REC8L1 antibody
  • Rec8p antibody

Protein level used designations for REC8 Homolog (Yeast) (REC8) ELISA Kits

REC8 homolog (yeast) , meiotic recombination protein REC8 homolog , REC8-like 1 , cohesin Rec8p , meiotic cohesion Rec8 , REC8 homolog , cohesion rec8p , human homolog of rad21, S. pombe , kleisin-alpha , meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family , meiotic recombination protein REC8-like 1 , recombination and sister chromatid cohesion protein homolog , meiosis specific sister chromatid cohesion protein

100581128 Nomascus leucogenys
490622 Canis lupus familiaris
516291 Bos taurus
56739 Mus musculus
100127457 Sus scrofa
100713854 Cavia porcellus
9985 Homo sapiens
290227 Rattus norvegicus
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