anti-R-Spondin 1 (RSPO1) Antibodies

RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. Additionally we are shipping R-Spondin 1 Kits (28) and R-Spondin 1 Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RSPO1 284654 Q2MKA7
RSPO1 313589  
RSPO1 192199 Q9Z132
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Top anti-R-Spondin 1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using R-spondin1 mouse mAb against recombinant R-spondin1 protein (1) and R-spondin1 (aa21-263) -hIgGFc transfected HEK293 cell lysate (2) . 100 μL Log in to see 2 to 3 Days
$393.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Mouse Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$163.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using RSPO1 antibody. Immunohistochemistry of paraffin-embedded rat lung using RSPO1 antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: R-Spondin 1 Antibody [NBP1-77354] - Rat spleen tissue lysate with RSPO1 antibody at (A) 1 and (B) 2 ug/mL. Immunohistochemistry: R-Spondin 1 Antibody [NBP1-77354] - Analysis of RSPO1 in human heart tissue with RSPO1 antibody at 2.5 ug/ml. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Mouse Un-conjugated IHC, WB Western Blot: R-Spondin 1 Antibody (11A9) [NBP2-45636] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY R-Spondin 1. Immunohistochemistry: R-Spondin 1 Antibody (11A9) [NBP2-45636] - Analysis of Human lymph node tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

RSPO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Rat (Rattus)


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Mouse (Murine) , ,


Top referenced anti-R-Spondin 1 Antibodies

  1. Human Polyclonal RSPO1 Primary Antibody for EIA, IHC (p) - ABIN615699 : Kim, Zhao, Andarmani, Kakitani, Oshima, Binnerts, Abo, Tomizuka, Funk: R-Spondin proteins: a novel link to beta-catenin activation. in Cell cycle (Georgetown, Tex.) 2006 (PubMed)
    Show all 4 references for 615699

  2. Human Monoclonal RSPO1 Primary Antibody for ELISA, WB - ABIN969375 : Parma, Radi, Vidal, Chaboissier, Dellambra, Valentini, Guerra, Schedl, Camerino: R-spondin1 is essential in sex determination, skin differentiation and malignancy. in Nature genetics 2006 (PubMed)
    Show all 2 references for 969375

  3. Human Monoclonal RSPO1 Primary Antibody for WB - ABIN1108910 : Tomaselli, Megiorni, De Bernardo, Felici, Marrocco, Maggiulli, Grammatico, Remotti, Saccucci, Valentini, Mazzilli, Majore, Grammatico: Syndromic true hermaphroditism due to an R-spondin1 (RSPO1) homozygous mutation. in Human mutation 2008 (PubMed)
    Show all 2 references for 1108910

  4. Human Polyclonal RSPO1 Primary Antibody for ELISA, WB - ABIN1998219 : Kamata, Katsube, Michikawa, Yamada, Takada, Mizusawa: R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. in Biochimica et biophysica acta 2004 (PubMed)

More Antibodies against R-Spondin 1 Interaction Partners

Human R-Spondin 1 (RSPO1) interaction partners

  1. Results showed that Rspo1 expression is downregulated in adult follicles but its activation is sufficient in promoting ovarian tumors supporting its direct involvement in the initiation of ovarian cancers.

  2. We highlight the cooperation of WNT4 (show WNT4 Antibodies), RSPO1 and FOXL2 (show FOXL2 Antibodies) within a regulatory network and the need for further research to better understand their role in defining and maintaining ovarian identity.

  3. Rspo1 glycosylation at Asn137 is essential for secretion and stability but not for heparin binding.

  4. DPY19L3-mediated C-mannosylation of Rspo1 at tryptophan(156) is required for Rspo1 secretion.

  5. Genetic variants in ZC3H11B, RSPO1, and GJD2 are associated with susceptibility to the development of high myopia in a Han Chinese population.

  6. R-Spondin1 has an effect on radiosensitivity of glioma cells

  7. ZNRF3 (show ZNRF3 Antibodies) and LGR4 (show LGR4 Antibodies)-binding sites in RSPO1 are required for Wnt (show WNT2 Antibodies) signaling.

  8. Changes in the expression levels of IRS1 (show IRS1 Antibodies), IRS2 (show IRS2 Antibodies), RIPK2 (show RIPK2 Antibodies), RSPO1, and DNA JC15 genes might contribute to the development of insulin (show INS Antibodies) resistance and glucose intolerance in the obese boys.

  9. the LGR4-Rspo1 complex crystal structure shows divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors

  10. ZNRF3 (show ZNRF3 Antibodies) binds RSPO1 and LGR5 (show LGR5 Antibodies)-RSPO1 with micromolar affinity via RSPO1 furin (show FURIN Antibodies)-like 1 (Fu1) domain.

Mouse (Murine) R-Spondin 1 (RSPO1) interaction partners

  1. In Rspo1 knock-out mice during pregnancy, a stronger expression of mesenchymal markers was observed, without modifications to the structure of mammary epithelial tissue. Mammary epithelial cell immunohistochemical analysis revealed a persistence of virgin markers, which signify a delay in cell differentiation.

  2. RSPO-LGR4 (show LGR4 Antibodies)/5-ZNRF3 (show ZNRF3 Antibodies)/RNF43 (show RNF43 Antibodies) module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.

  3. Rspo1 and its receptor of leucine-rich repeat containing G-protein-coupled receptor 4 (Lgr4 (show LGR4 Antibodies)) should be a novel molecular signal in the transmission of mechanical stimuli to biological signal in the bone, and this signal should be in the upstream of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling for bone formation.

  4. We also show that R-spondin1 is depleted in RANK-null progenitors, and that its exogenous administration rescues key aspects of RANK deficiency by reinstating a WNT (show WNT2 Antibodies) response and mammary cell expansion

  5. R-spondin 1/dickkopf-1 (show DKK1 Antibodies)/beta-catenin (show CTNNB1 Antibodies) machinery is involved in testicular embryonic angiogenesis

  6. The ascl2 (show ASCL2 Antibodies) is regulated in a direct autoactivatory loop, leading to a distinct on/off expression pattern, and Wnt (show WNT2 Antibodies)/R-spondin can activate this regulatory loop.

  7. RSPO1, WNT4 (show WNT4 Antibodies), and beta-catenin (show CTNNB1 Antibodies) have roles in the signaling pathway during ovarian differentiation in mice.

  8. Rspo1 is required for ovarian differentiation by activation of the WNT (show WNT2 Antibodies)/CTNNB1 (show CTNNB1 Antibodies) signalling pathway

  9. Rspo1 is involved in maintenance of the immature state of the progenitors of the granulosa cells of the ovary

  10. this study identifies Rspo1 and Wnt4 (show WNT4 Antibodies) as two new regulators of cell proliferation in the early gonad regardless of its sex, in addition to the specific role of these genes in ovarian differentiation.

R-Spondin 1 (RSPO1) Antigen Profile

Protein Summary

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

Gene names and symbols associated with anti-R-Spondin 1 (RSPO1) Antibodies

  • R-spondin 1 (RSPO1) antibody
  • R-spondin 1 (Rspo1) antibody
  • R-spondin 1 (LOC100049655) antibody
  • R-spondin homolog (Xenopus laevis) (Rspo1) antibody
  • CRISTIN3 antibody
  • R-spondin antibody
  • RGD1565558 antibody
  • RSPO antibody
  • Rspondin antibody

Protein level used designations for anti-R-Spondin 1 (RSPO1) Antibodies

R-spondin homolog , R-spondin-1 , roof plate-specific spondin-1 , ovarian R-spondin member 1 , R-spondin1 , cristin-3 , cysteine-rich and single thrombospondin domain-containing protein 3 , mCristin-3 , thrombospondin type 1 domain containing gene Rspondin

GENE ID SPECIES
284654 Homo sapiens
313589 Rattus norvegicus
100734447 Cavia porcellus
100860770 Capra hircus
100049655 Sus scrofa
608179 Canis lupus familiaris
511675 Bos taurus
419613 Gallus gallus
192199 Mus musculus
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