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expressed in GH3 pituitary cells [RGD, Feb 2006].. Additionally we are shipping RWD Domain Containing 3 Antibodies (39) and many more products for this protein.
Showing 8 out of 8 products:
RSUME affects post-transcriptional expression of HIF-1a (show HIF1A Proteins) by regulating VEGF-A (show VEGFA Proteins) secretion and pituitary adenoma cells invasiveness.
the present report suggest that the association of RWDD3 and TECTA with paclitaxel-induced peripheral neuropathy may have been a false positive signal
an important role of RSUME in cancer and inflammation
RSUME is expressed in VHL (show VHL Proteins) tumors and inhibits VHL (show VHL Proteins) and regulates its tumor suppressor function.
this study failed to replicate a GWAS reporting an association between the 2 SNPs rs2296308 in RWDD3 and rs1829 in the intron of TECTA and time to neuropathy in ovarian cancer patients treated with paclitaxel
a degree of redundancy of the RSUME variants on the SUMO pathway
RSUME interacts with glucocorticoid receptor and increases its SUMOylation and transcriptional activity, pointing to SUMO conjugation as the cause for transcriptional stimulation.
RSUME critically regulates HIF-1a (show HIF1A Proteins) and VEGF-A (show VEGFA Proteins) production and thus might play an important role in pituitary tumour neovascularisation
RSUME plays a central role in the regulation of sumoylation and, hence, several critical regulatory pathways in mammalian cells [RSUME].
BMP-4 (show BMP4 Proteins) and RSUME may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.
expressed in GH3 pituitary cells
RWD domain containing 3
, RWD domain-containing protein 3
, RWD-containing sumoylation enhancer
, RWD domain-containing sumoylation enhancer
, pituitary tumor X2CR1 protein