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expressed in GH3 pituitary cells. Additionally we are shipping RWD Domain Containing 3 Proteins (8) and many more products for this protein.
Showing 10 out of 37 products:
Human Polyclonal RWDD3 Primary Antibody for EIA, WB - ABIN783831
Carbia-Nagashima, Gerez, Perez-Castro, Paez-Pereda, Silberstein, Stalla, Holsboer, Arzt: RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. in Cell 2007
RSUME affects post-transcriptional expression of HIF-1a (show HIF1A Antibodies) by regulating VEGF-A (show VEGFA Antibodies) secretion and pituitary adenoma cells invasiveness.
the present report suggest that the association of RWDD3 and TECTA (show TECTA Antibodies) with paclitaxel-induced peripheral neuropathy may have been a false positive signal
an important role of RSUME in cancer and inflammation
RSUME is expressed in VHL (show VHL Antibodies) tumors and inhibits VHL (show VHL Antibodies) and regulates its tumor suppressor function.
this study failed to replicate a GWAS reporting an association between the 2 SNPs rs2296308 in RWDD3 and rs1829 in the intron of TECTA (show TECTA Antibodies) and time to neuropathy in ovarian cancer patients treated with paclitaxel
a degree of redundancy of the RSUME variants on the SUMO pathway
RSUME interacts with glucocorticoid receptor and increases its SUMOylation and transcriptional activity, pointing to SUMO conjugation as the cause for transcriptional stimulation.
RSUME critically regulates HIF-1a (show HIF1A Antibodies) and VEGF-A (show VEGFA Antibodies) production and thus might play an important role in pituitary tumour neovascularisation
RSUME plays a central role in the regulation of sumoylation and, hence, several critical regulatory pathways in mammalian cells [RSUME].
BMP-4 (show BMP4 Antibodies) and RSUME may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.
expressed in GH3 pituitary cells
RWD domain containing 3
, RWD domain-containing protein 3
, RWD-containing sumoylation enhancer
, RWD domain-containing sumoylation enhancer
, pituitary tumor X2CR1 protein