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Proteins of the large Rab GTPase family (see RAB1A\; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. Additionally we are shipping Rab11 Family-Interacting Protein 1 Antibodies (27) and Rab11 Family-Interacting Protein 1 Kits (3) and many more products for this protein.
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REI/SH3BP5 protein family is conserved in evolution and is a group of new guanine nucleotide exchange factors for Rab11.
Rab11-FIP1A associates with and regulates trafficking at an early step in the process of membrane recycling
GTPase (show RACGAP1 Proteins) Rab11 (show RAB11A Proteins), but not Rab4 (show RAB4A Proteins), is involved in the recycling of hERG (show KCNH2 Proteins) channels.
We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes.
rab11 (show RAB11A Proteins) effector protein FIP1 regulates adiponectin (show ADIPOQ Proteins) trafficking and secretion
Mitochondrial remodeling was associated with increased proximity between Rab11a and mitochondrial membranes, changes in fusion-fission dynamics, and mitochondrial relocalization of the Drp1, which was regulated by the Rab11a effector protein FIP1/RCP.
findings support a model for HIV-1 Env (show ERVW-1 Proteins) incorporation in which specific targeting to the particle assembly microdomain on the plasma membrane is mediated by FIP1C and Rab14 (show RAB14 Proteins)
These findings suggest that Rab11-FIP1 proteins participate in spatially and temporally distinct steps of the recycling process along a complex and dynamic tubular network in which Rab11-FIPs occupy discrete domains
Rab11 is differentially phosphorylated by distinct PKC isoenzymes; this post-translational modification might be a regulatory mechanism of intracellular trafficking.
results suggest that Rab5 (show RAB5A Proteins) is involved in CB2 (show CNR2 Proteins) endocytosis and that internalized receptors are recycled via a Rab11 (show RAB11A Proteins) associated pathway rather than the rapid Rab4 (show RAB4A Proteins) associated pathway.
Proteins of the large Rab GTPase family (see RAB1A\; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP1 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001
RAB11 family interacting protein 1 (class I)
, rab11 family-interacting protein 1
, Rab11 family interaction protein 1
, RAB11 coupling protein
, Rab effector protein
, Rab-interacting recycling protein
, rab-coupling protein
, Rab coupling protein