Receptor-Associated Protein of The Synapse (RAPSN) ELISA Kits

RAPSN encodes a member of a family of proteins that are receptor associated proteins of the synapse. Additionally we are shipping Receptor-Associated Protein of The Synapse Antibodies (48) and Receptor-Associated Protein of The Synapse Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RAPSN 5913 Q13702
RAPSN 19400 P12672
Anti-Rat RAPSN RAPSN 362161  
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Top Receptor-Associated Protein of The Synapse ELISA Kits at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.55 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 13 to 16 Days
$606.32
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Human
  96 Tests Log in to see 15 to 18 Days
$875.60
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Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

More ELISA Kits for Receptor-Associated Protein of The Synapse Interaction Partners

Human Receptor-Associated Protein of The Synapse (RAPSN) interaction partners

  1. These findings uncover a new link between rapsyn, lysosome positioning, exocytosis and plasma membrane integrity.

  2. a mutation of the RAPSN gene may have a role in development of congenital myasthenic syndrome after general anaesthesia [case report]

  3. Investigation of mutations in RAPSN determines that patients with congenital myasthenic syndrome can be misdiagnosed with seronegative myasthenia gravis.

  4. An allelic quantification on patient's DNA identified three novel multi-exon deletions of RAPSN.

  5. nAChR (show CHRNA4 ELISA Kits) mobility in plasma membranes of myoblast cells during their differentiation to myotubes in the presence and absence of rapsyn

  6. Rapsyn mutations in humans cause endplate acetylcholine-receptor (show CHRNA1 ELISA Kits) deficiency and myasthenic syndrome

  7. E-box mutations in the RAPSN promoter region may have a role in congenital myasthenic syndrome

  8. Four patients from four different families with RAPSN mutations and congenital myasthenic syndrome

  9. Rapsyn is essential for clustering the acetylcholine receptor (show CHRNA1 ELISA Kits) at the postsynaptic membrane of the neuromuscular junction.

  10. recombination events may have occurred within the rapsyn gene and that this may have implications in the phenotypic expression of postsynaptic congenital myasthenic syndrome

Mouse (Murine) Receptor-Associated Protein of The Synapse (RAPSN) interaction partners

  1. The RING domain of rapsyn contains E3 ligase activity. Mutation of the RING domain that abolishes the enzyme activity inhibits rapsyn- as well as agrin (show AGRN ELISA Kits)-induced AChR clustering in heterologous and muscle cells. Further biological and genetic studies support a working model where rapsyn, a classic scaffold protein (show HOMER1 ELISA Kits), serves as an E3 ligase to induce AChR clustering and NMJ formation, possibly by regulation of AChR neddylation

  2. Protein kinase CK2 (show CSNK2A1 ELISA Kits) interacts at the neuromuscular synapse with Rapsyn, Rac1, 14-3-3gamma (show YWHAG ELISA Kits), and Dok-7 (show DOK7 ELISA Kits) proteins and phosphorylates the latter two.

  3. Plectin (show PLEC ELISA Kits) bridges acetylcholine receptors and intermediate filaments via direct interaction with the AChR-scaffolding protein rapsyn in an isoform-specific manner.

  4. Molecular modelling, immunoprecipitation and bimolecular fluorescence complementation approaches identify an alpha-helical stretch of rapsyn to be crucial for binding to the dimerisation and docking domain of PKA type I.

  5. typical anchoring proteins of central excitatory synapses coimmunoprecipitate and colocalize with rapsyn

  6. alpha-Actinin (show ACTN1 ELISA Kits), rapsyn, and surface AChR form a ternary complex.

  7. nAChR (show CHRNA4 ELISA Kits) mobility in plasma membranes of myoblast cells during their differentiation to myotubes in the presence and absence of rapsyn

  8. These results provide the first experimental evidence that rapsyn is a direct sequence-specific target of Kaiso (show ZBTB33 ELISA Kits) and delta-catenin (show CTNND2 ELISA Kits).

  9. Thus, the metabolic half-life of receptors at the synapse may be modulated by local changes in the subsynaptic ratio of rapsyn to AChR.

  10. Remarkable dynamism of rapsyn underlies stability and maintenance of the postsynaptic scaffold and suggests that the insertion of different postsynaptic proteins may be operating independently.

Zebrafish Receptor-Associated Protein of The Synapse (RAPSN) interaction partners

  1. Our findings indicate that the reduced postsynaptic receptor density resulting from defective rapsyn contributes to weakness, but is not solely responsible for use-dependent fatigue

Receptor-Associated Protein of The Synapse (RAPSN) Antigen Profile

Antigen Summary

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with RAPSN

  • receptor-associated protein of the synapse (RAPSN) antibody
  • receptor-associated protein of the synapse (rapsn) antibody
  • receptor-associated protein of the synapse (Rapsn) antibody
  • receptor-associated protein of the synapse, 43kD (rapsn) antibody
  • 43kDa antibody
  • Nraps antibody
  • Raps antibody
  • RAPSN antibody
  • rapsyn antibody
  • RNF205 antibody

Protein level used designations for RAPSN

receptor-associated protein of the synapse , 43 kD receptor-associated protein of the synapse , 43 kDa receptor-associated protein of the synapse-like , 43 kDa postsynaptic protein , 43 kDa receptor-associated protein of the synapse , acetylcholine receptor-associated 43 kDa protein , rapsyn , receptor-associated protein of the synapse, 43kD , 43 kda postsynaptic protein , RING finger protein 205 , acetylcholine receptor-associated 43 kda protein , 43kDa acetylcholine receptor-associated protein , receptor-associated protein of the synapse, 43 kDa , twitch once , two

GENE ID SPECIES
451705 Pan troglodytes
100051540 Equus caballus
100397914 Callithrix jacchus
100447845 Pongo abelii
100579467 Nomascus leucogenys
399137 Xenopus laevis
395986 Gallus gallus
5913 Homo sapiens
609725 Canis lupus familiaris
541061 Bos taurus
19400 Mus musculus
362161 Rattus norvegicus
352942 Danio rerio
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